scholarly journals 68Ga-DOTATOC-PET/CT–guided resection of a primary intraosseous meningioma: technical note

2021 ◽  
Vol 50 (1) ◽  
pp. E6
Author(s):  
Gerardo Y. Guinto-Nishimura ◽  
Juan L. Gómez-Amador ◽  
Nora Kerik-Rotenberg ◽  
Rodrigo Uribe-Pacheco ◽  
Marcos V. Sangrador-Deitos ◽  
...  

Primary intraosseous meningiomas (PIMs) are rare tumors that present with a variable radiological appearance and a clinical behavior that is considerably different from that of intracranial meningiomas. Treatment of PIMs consists of complete resection, which may be difficult to achieve due to the lack of clear tumor margins on conventional imaging studies. PET/CT using 68Ga-DOTA–conjugated peptides has been used for the diagnosis and treatment planning of different types of meningiomas due to these tracers’ affinity to somatostatin receptors, which are found in most meningiomas. However, this imaging modality’s use as an intraoperative adjunct has not been reported for PIMs. In this technical note, the authors describe a [68Ga-DOTA0-Tyr3]octreotide (68Ga-DOTATOC)-PET/CT–guided resection of a PIM. In this case, the area of increased uptake in the 68Ga-DOTATOC-PET/CT study extended well beyond the tumor margins identified on MRI. The patient’s pathology report confirmed the presence of tumor cells within peripheral bone, which macroscopically appeared normal. The authors propose 68Ga-DOTATOC-PET/CT as a valuable adjunct in the surgical management of PIMs and offer a reasonable justification for its use based on current evidence. Its use for intraoperative image guidance may aid neurosurgeons in achieving a complete resection, thus minimizing the risk of recurrence of this complex pathological entity.

2014 ◽  
Vol 4 ◽  
pp. 54 ◽  
Author(s):  
Carina Mari Aparici ◽  
Rizwan Aslam ◽  
Aung Zaw Win

Objectives: Nonreal-time Positron Emission Tomography/Computed Tomography (PET/CT) biopsies that use the image co-registration of a prior PET with an intra-procedural CT have been reported. The aim of this study was to report the initial experience of performing real-time intra-procedural PET/CT-guided biopsies. Materials and Methods: All patients (n = 4) had a prior PET/CT examination of the concerning lesion and no significant CT correlate. On the day of the biopsy, 5 mCi of 18F-fluorodeoxyglucose (FDG) or NaF18 was intravenously injected. After 60 min of biodistribution of the molecular probe, PET/CT images were obtained in a limited one bed position over the region of the concerning lesion to be biopsied. Results: One patient had a mesenteric mass and the other three had bone lesions, one located in the rib and two in the iliac bone. The pathology report revealed that two lesions (50%) were malignant and two lesions (50%) were benign. The results of the biopsy changed management in all cases. There was 0% complication rate. Conclusions: No additional software or hardware is required to perform real-time intra-procedural PET/CT-guided biopsies. It can optimize the yield, especially in cases where there are no anatomical abnormalities. Real-time intra-procedural PET/CT biopsy may have benefits over conventional biopsy techniques in terms of accuracy.


2016 ◽  
Vol 39 (9) ◽  
pp. 1315-1321 ◽  
Author(s):  
Roberto Luigi Cazzato ◽  
Julien Garnon ◽  
Nitin Ramamurthy ◽  
Georgia Tsoumakidou ◽  
Alessio Imperiale ◽  
...  

Author(s):  
Judit A. Adam ◽  
Hester Arkies ◽  
Karel Hinnen ◽  
Lukas J. Stalpers ◽  
Jan H. van Waesberghe ◽  
...  

2000 ◽  
Vol 42 (11) ◽  
pp. 838-841 ◽  
Author(s):  
G. A. Krombach ◽  
T. Schmitz-Rode ◽  
B. B. Wein ◽  
J. Meyer ◽  
J. E. Wildberger ◽  
...  

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 636
Author(s):  
Masato Tanaka ◽  
Sumeet Sonawane ◽  
Koji Uotani ◽  
Yoshihiro Fujiwara ◽  
Kittipong Sessumpun ◽  
...  

Background: Percutaneous biopsy under computed tomography (CT) guidance is a standard technique to obtain a definitive diagnosis when spinal tumors, metastases or infections are suspected. However, specimens obtained using a needle are sometimes inadequate for correct diagnosis. This report describes a unique biopsy technique which is C-arm free O-arm navigated using microforceps. This has not been previously described as a biopsy procedure. Case description: A 74-year-old man with T1 vertebra pathology was referred to our hospital with muscle weakness of the right hand, clumsiness and cervicothoracic pain. CT-guided biopsy was performed, but histopathological diagnosis could not be obtained due to insufficient tissue. The patient then underwent biopsy under O-arm navigation, so we could obtain sufficient tissue and small cell carcinoma was diagnosed on histopathological examination. A patient later received chemotherapy and radiation. Conclusions: C-arm free O-arm navigated biopsy is an effective technique for obtaining sufficient material from spine pathologies. Tissue from an exact pathological site can be obtained with 3-D images. This new O-arm navigation biopsy may provide an alternative to repeat CT-guided or open biopsy.


2012 ◽  
Vol 23 (3) ◽  
pp. S31
Author(s):  
R. Ryan ◽  
R.H. Thornton ◽  
C.T. Sofocleous ◽  
J.P. Erinjeri ◽  
Q. Brian ◽  
...  
Keyword(s):  

2019 ◽  
Vol 103 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Alexander Soldatov ◽  
Christoph A.J. von Klot ◽  
Daniel Walacides ◽  
Thorsten Derlin ◽  
Frank M. Bengel ◽  
...  

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