Impact of ischemic heart disease and atrial fibrillation on survival after spontaneous intracerebral hemorrhage

2008 ◽  
Vol 108 (6) ◽  
pp. 1172-1177 ◽  
Author(s):  
Sami Tetri ◽  
Liisa Mäntymäki ◽  
Seppo Juvela ◽  
Pertti Saloheimo ◽  
Juhani Pyhtinen ◽  
...  

Object The well-known predictors for increased early deaths after spontaneous intracerebral hemorrhage (ICH) include the clinical and radiological severity of bleeding as well as being on a warfarin regimen at the onset of stroke. Ischemic heart disease and atrial fibrillation may also increase early deaths. In the present study the authors aimed to elucidate the role of the last 2 factors. Methods The authors assessed the 3-month mortality rate in patients with spontaneous ICH (453 individuals) who were admitted to the stroke unit of Oulu University Hospital within a period of 11 years (1993–2004). Results The 3-month mortality rate for the 453 patients was 28%. The corresponding mortality rates were 42% for the patients who had ischemic heart disease and 61% for those with atrial fibrillation on admission. The following independent predictors of death emerged after adjustment for sex and the use of warfarin or aspirin at the onset of ICH: 1) ischemic heart disease (hazard ratio [HR] 1.67, 95% confidence interval [CI] 1.12–2.48, p < 0.02); 2) atrial fibrillation on admission (HR 1.79, 95% CI 1.12–2.86, p < 0.02); 3) the Glasgow Coma Scale score on admission (HR 0.82 per unit, 95% CI 0.79–0.87, p < 0.01); 4) size of hematoma (HR 1.11 per 10 ml, 95% CI 1.07–1.16, p < 0.01); 5) intraventricular hemorrhage (HR 2.62, 95% CI 1.71–4.02, p < 0.01); 6) age (HR 1.04 per year, 95% CI 1.02–1.06, p < 0.01); and 7) infratentorial location of the hematoma (HR 1.93, 95% CI 1.26–2.97, p < 0.01). Conclusions Both ischemic heart disease and atrial fibrillation independently and significantly impaired the 3-month survival of patients with ICH.

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
A Gokce ◽  
A Ozer ◽  
V Soyiler ◽  
ME Gundogdu

Abstract Background The population aged ≥65 is important because of the higher mortality rate and a riskier clinical course of COVID-19 in this patient group. This study aimed to examine the epidemiological characteristics, clinical conditions and factors affecting the clinical status of patients over 65 with COVID-19 in the Bingol province. Methods Study was conducted between March and December 2020 in the Bingol province using the data of 3,521 patients over age 65 who were positive for SARS-CoV-2 as per RT-PCR results. The study commenced after obtaining necessary institutional permissions and the ethics committee approval. In the study, independent variables were age, gender, presence of chronic diseases whereas dependent variables were mortality status, presence of pneumonia. Chi-square test and binominal logistic regression analysis were used for statistical analysis. In all evaluations, p &lt; 0.05 was considered significant. Results The median age of the patients participating in the study was 72(65-102) and the case fatality rate was 2%. The mortality rates were significantly higher in patients aged between 75-84 and those aged &gt;85 as well as patients who had a chronic disease, diabetes and ischemic heart disease compared to the other groups (p &lt; 0.05). According to the regression analysis, mortality rate was 2.6-fold higher in males than in females and 24.3-fold higher in patients with pneumonia than in those without pneumonia (p &lt; 0.05). Conclusions Among the patients in the study group, mortality rate was found to be higher in males, those in the advanced age group and those with pneumonia and chronic diseases. Therefore, if possible, patients with these characteristics should be followed more closely in a hospital setting during the pandemic. Key messages Mortality rates are higher in patients with COVID-19 who have a chronic disease, diabetes or ischemic heart disease. Age, gender and presence of pneumonia are among the important factors in the course of COVID-19.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Ortiz-Pinto ◽  
B Pérez-Gómez ◽  
I Galán ◽  
R Sarmiento-Suárez ◽  
T Gómez-García ◽  
...  

Abstract Background Our aim was to test the usefulness of a new tool to monitor NCD. We evaluated a composite indicator, the ratio of hospitalizations vs mortality rates (HMR), by assessing its capacity of identifying additional variability among regions. In this communication, we present the analysis corresponding to ischemic heart disease as an example. Methods We used the Hospital Morbidity Survey and the Death Statistics for Spain in 2016, both provided by the National Institute of Statistics, to calculate age-adjusted hospitalisation and mortality rates for ischemic heart disease for men and women in all 52 provinces of Spain. Subsequently, we computed HMR, the ratio of the age-adjusted of hospital morbidity and mortality rates. The correlation and linear adjustment between provincial mortality and morbidity rates, as well as mortality and HMR, were also estimated by sex. Results The rate of hospital admissions for ischemic heart disease in Spain was 407 per 100,000 in men and 129.4 in women. The mortality rate was 93.1 per 100,000 in men and 40.3 in women. In both sexes, the highest morbidity and mortality rates were observed in the south of Spain. Pearson correlation between morbidity and mortality rates were 0.53 (p &lt; 0.01) in men and 0.75 (p &lt; 0.05) in women. HMR showed a different spatial pattern with important variability. In men the average ratio was 4.3, with a range of 2.8 (Tenerife) to 7.1 (Melilla); in women the average was 3.2 with a range between1.7 (Zamora and Tenerife) and 4.7 (Barcelona), and in both sexes very high ratios were found in Catalonia's provinces. Association between mortality rate and HMR showed a negative correlation in both men (-0.39; p &lt; 0.01) and women (-0.24; p &lt; 0.05). Conclusions HMR is a composite indicator that provides complementary information regarding the individual analysis of hospital morbidity and mortality rates. HMR of ischemic heart disease shows an important geographical variability and an inverse association with mortality.


Author(s):  
Al-Aghbari Khaled ◽  
Bamashmoos Mohammed ◽  
Askar Faiza

Objectives: The aim of the study is to Determine, prevalence, possible risk factors, aetiology and outcome of patient with atrial fibrillation admitted into medical and cardiac units at Kuwait University hospital during 2014-2017. Methods and patients: Cross sectional retrospective review of all files of patients admitted to hospital during 2014 t0 2017. We reviewed 2030 Cardiac cases among which 179 were atrial fibrillation. Special form was designed to record general characters, risk factors & out come during hospitalization. Results: The prevalence of atrial fibrillation (A F) was 8% (179/2030). The male to female ratio was 5:4 and their main age was 54±9. The common risk factors were ischemic heart disease, Qat chewer, hyperlipidemia, rheumatic heart disease and smoker represented to (46%,41%, 39%, 38%,38%) respectively. Transthoracic echo was performed for all patients and revealed that 92 (51.9%) had systolic dysfunction, while only 34(18.9%) patient had diastolic dysfunction. Mitral stenosis was detected in 30 (16.7%) patients among rheumatic heart disease (RHD). Regarding outcome of AF we found that 137(77%) was improved and discharged, while 42 (13.4%) was expired, however, 18 patients (10%) was referred to other hospitals. Conclusion: The prevalence of AF in this study was higher than that reported from other countries, and occurred in younger age group. Ischemic heart disease and RHD were prominent risk factors for AF in this study.


2017 ◽  
Vol 4 (1) ◽  
pp. 5-12
Author(s):  
Ram Narayan Mandal ◽  
Ajay Kumar Mishra ◽  
Elena Leonidovna Mandal

Background and Objectives: Atrial fibrillation (AF) is a frequently encountered cardiac arrhythmia which may be either symptomatic or asymptomatic. So, this study was conducted to know clinical presentation and to find out possible clinical and etiological profile of patients with AF.Material and Methods: This cross sectional study was conducted at Osh Regional Integrated Clinical Hospital, Osh Territorial City Clinical Hospital, The Kyrgyz Republic in collaboration with Janaki Medical College Teaching Hospital, Janakpurdham, Nepal. Sixty consecutive patients with AF were taken. Presenting complaints, past history, personal history was recorded. A thorough clinical examination was done, electrocardiogram, chest X-Ray posterio-anterior view, echocardiogram, thyroid function test and relevant test were done and analyzed.Results: Forty percent of the patients complained palpitation. Systemic thrombo-embolism was found in 15% of the patients. Other presenting complaints were cough, chest pain, shortness of breath, dizziness, swelling of the legs, tremors. Eighteen percent of patients presented with features of congestive cardiac failure and 30% of the patients gave history of rheumatic heart disease, 16.6% and 11.6% hypertension and ischemic heart disease respectively. Etiology-wise, rheumatic heart disease was the most common (46.6%) followed by hypertension (21.6%), ischemic heart disease (11.6%), dilated cardiomyopathy (6.6%), hyperthyroidism (5%), pneumonia (5%).Conclusion: Rheumatic heart disease, especially mitral stenosis is the most common cause of AF in this study. Systemic hypertension was next common etiology of AF, followed by ischaemic heart disease, dilated cardiomyopathy, thyroid disease. Heart failure, Systemic thromboembolism, decreased exercise tolerance are a major determinants for development of significant morbidity and mortality.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 5-12


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