scholarly journals Giant Placental Chorioangioma with Intrauterine Fetal Death

2013 ◽  
Vol 52 (190) ◽  
Author(s):  
Hansa Dhar

Chorioangioma of the placenta is a common benign vascular tumour of the placenta consisting of blood vessels and stroma. Most of these tumours are small and have no adverse impact on the fetus. Large tumours are associated with complications affecting mother and the fetus which may cause intrauterine fetal death. Chorioangiomas probably act as peripheral shunts between arteries and veins (arteriovenous shunts) leading to progressive heart failure of the fetus. Prenatal diagnosis is achieved by ultrasonography and Doppler studies will confirm the highly vascular nature of the mass.As the tumour is associated with unfavourable effects on the mother and fetus like polyhydramnios, prematurity, toxaemia, hydrops and fetal heart failure pregnancy needs to have regular surveillance to detect and manage complications early. A case of giant placental chorioangioma in a primigravida associated with intrauterine fetal death at 30 weeks of gestation is reported._______________________________________________________________________________________Keywords: Chorioangioma, hydrops fetalis; intrauterine fetal death; placental tumors._________________________________________________________________________________

Development ◽  
1965 ◽  
Vol 13 (3) ◽  
pp. 235-241
Author(s):  
Miguel Marin-Padilla ◽  
Kurt Benirschke

Previously (Marin-Padilla & Benirschke, 1963) it was noted that some embryos of thalidomide-treated armadillos exhibited enlargement of the heart and liver and generalized congestion. These findings were interpreted as the result of fetal heart failure and were found only in embryos obtained from armadillos treated late in gestation. The heart failure of these embryos may have resulted from a loss of fetal fluid and possibly of fetal blood throughout the areas of placental damage induced by thalidomide. An elevated reticulocyte count and an increase in nucleated red cells were found in these embryos and were considered indicative of compensatory erythropoiesis. The heart failure and the placental damage were considered as possible causes of abortion. Fetal death, with resorption of young embryos or abortion of older embryos, has been the most common phenomenon reported after thalidomide administration to experimental animals (Marin-Padilla & Benirschke, 1963; Hay, 1964; Rickenbacher, 1963).


2021 ◽  
Vol 12 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Naoto Minamino

Fetal heart failure is mainly caused by congenital heart defect and arrhythmia. It is difficult to appropriately diagnose the severity of fetal heart failure simply by ultrasonography because the development of a fetal heart in fetoplacental circulation and how well the fetal myocardium can adapt to postnatal cardiopulmonary circulation are challenging to assess. In adult cardiology, natriuretic peptides (NPs) are the most useful biomarker of heart failure; however, studies investigating NP levels in the fetuses and amniotic fluid are quite limited. Furthermore, little is known about their production and metabolism. This review summarized the most relevant findings on NP levels in the umbilical cord blood and amniotic fluid. The findings can then extend their use as a diagnostic biomarker of heart failure in fetuses with congenital heart defect and/or arrhythmia.


Neurosurgery ◽  
1983 ◽  
Vol 13 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Leland A. Albright ◽  
Richard E. Latchaw ◽  
Robert A. Price

Abstract A 23-month-old infant with an extensive dural arteriovenous malformation (AVM) developed a heart murmur and cardiomegaly. The AVM involved the occipital and suboccipital dura mater and the tentorium, bilaterally. We embolized the AVM with Gelfoam and polyvinyl alcohol particulates, subtotally resected it, and embolized residual vessels with isobutyl cyanoacrylate, In spite of this extensive therapy, the malformation was not totally eradicated and an occipital pial AVM developed. This infant and the eight infants with posterior dural AVMs reported previously emphasize the difficulty of eradicating these lesions in infancy. We contrast the clinical features and therapy of infants and adults with posterior dural AVMs. Infants develop heart failure and cranial bruits beacause of arteriovenous shunts, whereas adults complain of headache and intracranial bruits. Infants need therapy to prevent progressive heart failure, intracranial hypertension, and perhaps cerebral ischemia. Ligation of arterial tributaries is inadequate therapy for these lesions. Embolization and resection of the malformation, when feasible, offers the best chance of curing posterior dural AVMs with extensive arterial tributaries.


10.2741/s109 ◽  
2010 ◽  
Vol S2 (3) ◽  
pp. 891-906 ◽  
Author(s):  
Lisa K Hornberger

2010 ◽  
Vol 53 (4) ◽  
pp. 915-929 ◽  
Author(s):  
JAMES C. HUHTA ◽  
JAMES J. PAUL

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Hendryk Schneider ◽  
Roland Hentschel ◽  
Kathrin Enderle-Ammour

Abstract Chorangioma is the most common benign tumor of the placenta. Tumors larger than 5 cm can cause adverse fetal outcomes. We describe the case of a term infant presenting with acute respiratory failure due to fetal heart insufficiency. In this particular case, the presence of a multifocal chorangiomatosis causing fetal heart failure was not diagnosed prenatally by ultrasound but first by the histopathological report of the placenta.


2019 ◽  
Vol 220 (1) ◽  
pp. 104.e1-104.e15 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Michikazu Nakai ◽  
Kunihiro Nishimura ◽  
Mikiya Miyazato ◽  
...  

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