Large multiple chorangiomas of the placenta causing acute neonatal respiratory failure

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Hendryk Schneider ◽  
Roland Hentschel ◽  
Kathrin Enderle-Ammour

Abstract Chorangioma is the most common benign tumor of the placenta. Tumors larger than 5 cm can cause adverse fetal outcomes. We describe the case of a term infant presenting with acute respiratory failure due to fetal heart insufficiency. In this particular case, the presence of a multifocal chorangiomatosis causing fetal heart failure was not diagnosed prenatally by ultrasound but first by the histopathological report of the placenta.

2021 ◽  
Vol 12 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Naoto Minamino

Fetal heart failure is mainly caused by congenital heart defect and arrhythmia. It is difficult to appropriately diagnose the severity of fetal heart failure simply by ultrasonography because the development of a fetal heart in fetoplacental circulation and how well the fetal myocardium can adapt to postnatal cardiopulmonary circulation are challenging to assess. In adult cardiology, natriuretic peptides (NPs) are the most useful biomarker of heart failure; however, studies investigating NP levels in the fetuses and amniotic fluid are quite limited. Furthermore, little is known about their production and metabolism. This review summarized the most relevant findings on NP levels in the umbilical cord blood and amniotic fluid. The findings can then extend their use as a diagnostic biomarker of heart failure in fetuses with congenital heart defect and/or arrhythmia.


10.2741/s109 ◽  
2010 ◽  
Vol S2 (3) ◽  
pp. 891-906 ◽  
Author(s):  
Lisa K Hornberger

2010 ◽  
Vol 53 (4) ◽  
pp. 915-929 ◽  
Author(s):  
JAMES C. HUHTA ◽  
JAMES J. PAUL

Development ◽  
1965 ◽  
Vol 13 (3) ◽  
pp. 235-241
Author(s):  
Miguel Marin-Padilla ◽  
Kurt Benirschke

Previously (Marin-Padilla & Benirschke, 1963) it was noted that some embryos of thalidomide-treated armadillos exhibited enlargement of the heart and liver and generalized congestion. These findings were interpreted as the result of fetal heart failure and were found only in embryos obtained from armadillos treated late in gestation. The heart failure of these embryos may have resulted from a loss of fetal fluid and possibly of fetal blood throughout the areas of placental damage induced by thalidomide. An elevated reticulocyte count and an increase in nucleated red cells were found in these embryos and were considered indicative of compensatory erythropoiesis. The heart failure and the placental damage were considered as possible causes of abortion. Fetal death, with resorption of young embryos or abortion of older embryos, has been the most common phenomenon reported after thalidomide administration to experimental animals (Marin-Padilla & Benirschke, 1963; Hay, 1964; Rickenbacher, 1963).


2019 ◽  
Vol 220 (1) ◽  
pp. 104.e1-104.e15 ◽  
Author(s):  
Takekazu Miyoshi ◽  
Hiroshi Hosoda ◽  
Michikazu Nakai ◽  
Kunihiro Nishimura ◽  
Mikiya Miyazato ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document