scholarly journals Lemierre's Syndrome in a Patient with Severe Lupus Nephritis

2011 ◽  
Vol 51 (183) ◽  
Author(s):  
B P Paudyal
Keyword(s):  
Lupus Nephritis ◽  
Host Response ◽  
Jugular Vein ◽  
Immunocompromised Patients ◽  
Lemierre’S Syndrome ◽  
Increased Risk ◽  
Oropharyngeal Infection ◽  
Severe Lupus Nephritis ◽  
Immunocompromised State ◽  
Lemierre's Syndrome

Lemierre’s syndrome is a rare septic thrombophlebitis of the internal jugular vein with frequent metastatic complications following an acute oropharyngeal infection. Immunocompromised patients are at higher risk of developing this syndrome owing to the decreased host response and increased risk of oropharyngeal sepsis. We herein report a 24-year-old woman with severe lupus nephritis on immunosuppressive therapy, who developed Lemierre’s syndrome following a pharyngeal infection despite an adequate and timely antibiotic therapy. We hereby draw an attention to the importance of accurate and timely diagnosis and appropriate management of Lemierre’s syndrome in immunocompromised patients so as to achieve a successful prognosis for this deadly infection. Keywords: Lemierre’s syndrome, lupus nephritis, immunocompromised state

scholarly journals A Case of Lemierre Syndrome Secondary to Otitis Media and Mastoiditis

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Aynur Turan ◽  
Harun Cam ◽  
Yeliz Dadali ◽  
Serdar Korkmaz ◽  
Ali Özdek ◽  
...  
Keyword(s):  
Otitis Media ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Anaerobic Bacteria ◽  
Transverse Sinus ◽  
Lemierre’S Syndrome ◽  
Lemierre Syndrome ◽  
Mortality And Morbidity ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Lemierre’s syndrome is a rare clinical condition that generally develops secondary to oropharyngeal infection caused byFusobacterium necrophorum, which is an anaerobic bacteria. A 62-year-old patient with diabetes mellitus presented with internal jugular vein and sigmoid sinus-transverse sinus thrombophlebitis, accompanying otitis media and mastoiditis that developed after an upper airway infection. Interestingly, there were air bubbles in both the internal jugular vein and transverse sinus. Vancomycin and meropenem were started and a right radical mastoidectomy was performed. The patient’s clinical picture completely resolved in 14 days. High mortality and morbidity may be prevented with a prompt diagnosis of Lemierre’s syndrome.

scholarly journals Lemierre’s Syndrome Associated with Mechanical Ventilation and Profound Deafness

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Lukas Birkner
Keyword(s):  
Mechanical Ventilation ◽  
Cochlear Implant ◽  
Jugular Vein ◽  
Lemierre’S Syndrome ◽  
Oropharyngeal Infection ◽  
Profound Deafness ◽  
Ventilation Support ◽  
Mechanical Ventilation Support ◽  
Life Threatening ◽  
Lemierre's Syndrome

Lemierre’s syndrome is a rare disorder that is characterized by anaerobic organisms inducing a thrombophlebitis of the internal jugular vein (IJV) following a course of oropharyngeal infection. It often occurs in young and healthy patients. Clinicians continuously misinterpret early symptoms until infection disseminates systematically and life-threatening sepsis transpires. We report the case of a 58-year-old female developing Lemierre’s syndrome accompanied by invasive ventilation support and a profound deafness requiring the implementation of a cochlear implant. This is one of two reported cases of Lemierre’s syndrome associated with mechanical ventilation support and the only case associated with a cochlear implant.

Lemierre's Syndrome: Postanginal Sepsis Due to Anaerobic Oropharyngeal Infection

1994 ◽  
Vol 103 (3) ◽  
pp. 208-210 ◽  
Author(s):  
Sunket Ahkee ◽  
Latha Srinath ◽  
Martin J. Raff ◽  
Anna Huang ◽  
Julio A. Ramirez
Keyword(s):  
Jugular Vein ◽  
Clinical Entity ◽  
Septic Thrombophlebitis ◽  
Lemierre’S Syndrome ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Lemierre's syndrome is an uncommon clinical entity. It consists of oropharyngeal infection and anaerobic bacteremia, followed by jugular vein septic thrombophlebitis with embolization to lungs and other areas. Although it occurs less frequently than in the preantibiotic era, it is important that the typical presentation be recognized because of its lethal potential. A case of Lemierre's syndrome in Louisville, Kentucky, is described.

scholarly journals Jugular vein thrombosis and anticoagulation therapy in Lemierre’s syndrome – a post-hoc observational and population-based study of 82 patients

2020 ◽  
Author(s):  
David Nygren ◽  
Johan Elf ◽  
Gustav Torisson ◽  
Karin Holm
Keyword(s):  
Jugular Vein ◽  
Anticoagulation Therapy ◽  
Population Based ◽  
Invasive Infection ◽  
Lemierre’S Syndrome ◽  
Jugular Vein Thrombosis ◽  
Septic Complications ◽  
Vein Thrombosis ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Abstract Background Lemierre’s syndrome is typically caused by Fusobacterium necrophorum where an oropharyngeal infection is followed by septic internal jugular vein thrombophlebitis with subsequent septic embolization. Yet, the pathogenesis of septic thrombophlebitis, differences dependent on presence of jugular vein thrombosis and the role of anticoagulant therapy are insufficiently understood. Methods Patients with invasive infection with F. necrophorum and Lemierre’s syndrome who had been investigated for jugular vein thrombosis were included from a previous population-based observational study in Sweden. Medical records were reviewed and compared in patients with and without jugular vein thrombosis. Then, patients with jugular vein thrombosis were compared by exposure to therapeutic, prophylactic or no anticoagulation. Outcomes examined were thrombosis progression, early or late peripheral septic complications, chronic major sequelae, 30-day mortality and major bleeding. Results 51/82 (62%) radiologically investigated patients with Lemierre’s syndrome had jugular vein thrombosis. Patients with jugular vein thrombosis had lower platelet levels (median 76 vs 112 x10^9/L, p=0.04) on presentation and more days to defervesence (12 vs. 7 days, p=0.03), yet similar rates of major sequelae and 30-day-mortality. No significant differences in outcomes were seen between patients with jugular vein thrombosis exposed to therapeutic, prophylactic or no anticoagulation therapy, yet study outcomes were rare. Conclusion Patients with Lemierre’s syndrome with jugular vein thrombosis were more severely affected, yet had similar prognosis. Most patients with jugular vein thrombosis recovered well without therapeutic anticoagulation therapy, though adverse events were similarly rare in anticoagulated patients. The observational design and rarity of study outcomes requires cautious interpretation.

scholarly journals Internal Jugular Vein and Transverse Sinus Thrombosis as a Complication of a Chronic Ethmoidal Sinusitis

2017 ◽  
Vol 2 (3) ◽  
pp. 7-9
Author(s):  
Kombate Damelan ◽  
ASSOGBA Komi ◽  
kumako vinyo ◽  
Diatewa E. Josué ◽  
Guinhouya Kokou Mensah ◽  
...  
Keyword(s):  
Internal Jugular Vein ◽  
Oral Anticoagulant ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Oral Anticoagulant Therapy ◽  
Transverse Sinus ◽  
Lemierre’S Syndrome ◽  
Young Males ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Lemierre’s syndrome is rare jugular thrombosis associated with an oropharyngeal infection. The jugular thrombosis is from septic origin. This often happens in young males subjects. We described Lemierre’s syndrome in a 46 year-old man with a chronic ethmoidal sinusitis associated to the left jugular thrombosis extended to the transverse sinus with a partial recanalisation after three months of oral anticoagulant therapy.

scholarly journals Lemierre's Syndrome Complicating Pregnancy

2007 ◽  
Vol 2007 ◽  
pp. 1-3 ◽  
Author(s):  
M. Thompson ◽  
A. O. Awonuga ◽  
J. Bell ◽  
C. Ray ◽  
M. T. Awonuga ◽  
...  
Keyword(s):  
Case Report ◽  
Jugular Vein ◽  
Premature Delivery ◽  
Second Trimester ◽  
Neurological Damage ◽  
Lemierre’S Syndrome ◽  
Atypical Case ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome ◽  
In Pregnancy

Lemierre's syndrome is an anaerobic suppurative thrombophlebitis involving the internal jugular vein secondary to oropharyngeal infection. There is only one previous case report in pregnancy which was complicated by premature delivery of an infant that suffered significant neurological damage. We present an atypical case diagnosed in the second trimester with a live birth at term. By reporting this case, we hope to increase the awareness of obstetricians to the possibility of Lemierre's syndrome when patients present with signs of unabating oropharyngeal infection and pulmonary symptoms.

scholarly journals Bilateral Lemierre's Syndrome: A Case Report and Literature Review

2002 ◽  
Vol 81 (4) ◽  
pp. 234-252 ◽  
Author(s):  
Brian A. Moore ◽  
Catherine Dekle ◽  
Jay Werkhaven
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Lemierre’S Syndrome ◽  
Jugular Vein Thrombosis ◽  
Jugular Veins ◽  
Vein Thrombosis ◽  
Warfarin Sodium ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Lemierre's syndrome is characterized by thrombosis of the internal jugular vein that develops following an oropharyngeal infection. Sepsis and septic metastases frequently ensue and affect the lungs, the musculoskeletal system, and occasionally the liver. Most cases are caused by infection with Fusobacterium necrophorum. This infection responds to antibiotic therapy with beta-lactamase-resistant compounds that exert good anaerobic coverage. Anticoagulation and surgical intervention can be helpful in advanced cases. Fewer than 160 cases of classic Lemierre's syndrome have been described; approximately one-third of these reported cases have occurred since 1988. We describe a new case of Lemierre's syndrome that occurred in an otherwise healthy 27-year-old man. Thrombosis of both internal jugular veins extended through the subclavian system and into both upper extremities. The patient was treated with intravenous antibiotics and heparin during 14 days of hospitalization. He was discharged on oral clindamycin and warfarin sodium, and after 6 months he was able to return to full activity. To our knowledge, this is the first reported case of Lemierre's syndrome in which internal jugular vein thrombosis occurred bilaterally. By reporting this previously undescribed manifestation of Lemierre's syndrome, we hope to increase practitioner awareness of this disease entity.

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