Manganese, Copper, Zinc, and Iron Concentrations and Subcellular Distribution in Two Types of Skeletal Muscle

Using normal rats, retention values and subcellular distribution of 67Ga in each organ were investigated. At 10 min after administration of 67Ga-citrate the retention value of 67Ga in blood was 6.77% dose/g, and this value decreased with time. The values for skeletal muscle, lung, pancreas, adrenal, heart muscle, brain, small intestine, large intestine and spinal cord were the highest at 10 min after administration, and they decreased with time. Conversely, this value in bone increased until 10 days after injection. But in the liver, kidney, and stomach, these values increased with time after administration and were highest 24 h or 48 h after injection. After that, they decreased with time. The value in spleen reached a plateau 48 h after administration, and hardly varied for 10 days. From the results of subcellular fractionation, it was deduced that lysosome plays quite an important role in the concentration of 67Ga in small intestine, stomach, lung, kidney and pancreas; a lesser role in its concentration in heart muscle, and hardly any role in the 67Ga accumulation in skeletal muscle. In spleen, the contents in nuclear, mitochondrial, microsomal, and supernatant fractions all contributed to the accumulation of 67Ga.

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Postnatal changes in subcellular distribution of copper, zinc and metallothionein in the liver of bank vole (Clethrionomys glareolus): a possible involvement of metallothionein and copper in cell proliferation

Comparative Biochemistry and Physiology Part C Comparative Pharmacology ◽

10.1016/0742-8413(92)90009-v ◽

1992 ◽

Vol 103 (2) ◽

pp. 285-290 ◽

Cited By ~ 2

Author(s):

T. Włostowski

Keyword(s):

Cell Proliferation ◽

Bank Vole ◽

Subcellular Distribution ◽

Clethrionomys Glareolus ◽

Copper Zinc

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Subcellular distribution of GLUT 4 in the skeletal muscle of lean type 2 (non-insulin-dependent) diabetic patients in the basal state

Diabetologia ◽

10.1007/bf02342444 ◽

1992 ◽

Vol 35 (5) ◽

pp. 456-463 ◽

Cited By ~ 25

Author(s):

B. Vogt ◽

C. Mühlbacher ◽

J. Carrascosa ◽

B. Obermaier-Kusser ◽

E. Seffer ◽

...

Keyword(s):

Skeletal Muscle ◽

Subcellular Distribution ◽

Diabetic Patients ◽

Glut 4 ◽

Insulin Dependent ◽

Insulin Dependent Diabetic

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A note on an effect of sodium monensinate supplements on the level of some chemical elements in the organs and muscle of feedlot steers

Animal Science ◽

10.1017/s0003356100040216 ◽

1985 ◽

Vol 40 (3) ◽

pp. 511-513 ◽

Cited By ~ 3

Author(s):

J. Mašek ◽

J. Gilka ◽

H. Dočekalovà

Keyword(s):

Chemical Elements ◽

Cadmium Content ◽

Monovalent Cations ◽

Feedlot Steers ◽

Polyvalent Cations ◽

Copper Zinc ◽

Manganese Copper

ABSTRACTIn muscle and livers of steers given a diet with sodium monensinate a significant decrease in cadmium content was observed. The concentration of manganese, copper, zinc, lead and iron in the analysed organs varied inconsistently. It seems from the results that, in tissues, monensinate influences the metabolism not only of monovalent cations but of polyvalent cations as well.

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