Assessment of Respiratory Rate in Dogs during the Sleep with Mitral Valve Endocardiosis, Complicated by Congestive Heart Failure Syndrome: the Degree of Adherence for this Test by Animal Owners and its Impact on Patient Survival

Purpose of the study. To study the owners' adherence to assessment of sleeping respiratory rate in cats with congestive heart failure and its effect on the survival of sick animals. Materials and methods. A retrospective study of the survival rate of 84 cats with congestive heart failure. Results. It was found that the degree of owners' adherence to the assessment of sleeping respiratory rate has a significant effect on the survival rate of cats with congestive heart failure. The median duration of life of sick cats, whose owners had a high adherence to monitoring a respiratory function, was significantly longer. It was determined that the low degree of owners' adherence to this problem is an independent predictor of the lethal outcome in cats with congestive heart failure. Conclusion. It is recommended to identify in a timely manner the factors of low diagnostic adherence among owners and to conduct explanatory work to improve it.

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Effects of treatment on respiratory rate, serum natriuretic peptide concentration, and Doppler echocardiographic indices of left ventricular filling pressure in dogs with congestive heart failure secondary to degenerative mitral valve disease and dilated cardiomyopathy

Journal of the American Veterinary Medical Association ◽

10.2460/javma.239.4.468 ◽

2011 ◽

Vol 239 (4) ◽

pp. 468-479 ◽

Cited By ~ 28

Author(s):

Karsten E. Schober ◽

Taye M. Hart ◽

Joshua A. Stern ◽

Xiaobai Li ◽

Valerie F. Samii ◽

...

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Mitral Valve ◽

Dilated Cardiomyopathy ◽

Respiratory Rate ◽

Mitral Valve Disease ◽

Left Ventricular ◽

Filling Pressure ◽

Ventricular Filling Pressure ◽

Ventricular Filling

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Treatment of Congestive Heart Failure with Intravenous Nitroglycerin in Three Dogs with Degenerative Valvular Disease

Journal of the American Animal Hospital Association ◽

10.5326/jaaha-ms-6730 ◽

2020 ◽

Vol 56 (1) ◽

pp. 37-41

Author(s):

Ron Achiel ◽

Andy Carver ◽

Robert A. Sanders

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Mitral Valve ◽

Adverse Events ◽

Respiratory Distress ◽

Intravenous Nitroglycerin ◽

Constant Rate Infusion ◽

Optimal Dosing ◽

Constant Rate ◽

Rate Infusion

ABSTRACT We described the use of IV nitroglycerin as adjunctive therapy in three canine patients with left congestive heart failure secondary to degenerative mitral valve disease. All three dogs were admitted for signs of respiratory distress and all were determined to be in left congestive heart failure by history, exam findings, thoracic radiographs, and echocardiography. In addition to standard therapy for left congestive heart failure, IV nitroglycerin was administered as a constant rate infusion at a dose of 1–6 mcg/kg/min. No adverse events attributable to the drug were noted. This is the first reported use of IV nitroglycerin in clinical veterinary patients. Further studies are warranted to investigate the safety, efficacy, and optimal dosing of IV nitroglycerin infusions in dogs with left congestive heart failure.

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Blood lactate increases with the progression of mitral valve disease in dogs

Pesquisa Veterinária Brasileira ◽

10.1590/1678-5150-pvb-5169 ◽

2018 ◽

Vol 38 (9) ◽

pp. 1781-1786

Author(s):

Jorge Cardoso Silva-Filho ◽

Marlos G. Sousa ◽

Evandro Zacché Pereira ◽

Edna M.G. Ortiz ◽

Rodrigo P. Franco ◽

...

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Mitral Valve ◽

Blood Lactate ◽

Cardiac Remodeling ◽

Mitral Valve Disease ◽

Lactate Concentration ◽

Tissue Perfusion ◽

Valve Disease ◽

Cross Sectional

ABSTRACT: In dogs with congestive heart failure, the upregulated sympathetic tone causes vasoconstriction that impairs peripheral blood supply, therefore causing the accumulation of lactate. In this prospective cross-sectional study with a longitudinal component, blood lactate was quantified in 10 healthy and 34 myxomatous mitral valve disease (MMVD) dogs to investigate its potential use as a diagnostic and prognostic biomarker. While there were no differences in lactate concentration between control animals and stages B1 (3.31±0.62mmol/L) and B2 (3.32±0.46mmol/L) dogs, significant differences were found between healthy (2.50±0.69mmol/L) and both C (3.99±0.47mmol/L) and D (6.97±1.23mmol/L) animals. When a cut-off of 3.35mmol/L was used, lactate was able to distinguish dogs with normal and remodeled hearts with a sensitivity of 78.2% and specificity of 63.6%. Also, significant correlations existed between lactate and indicators of cardiac remodeling. Finally, animals with blood lactate <3.5mmol/L carried a better prognosis when compared with dogs in which lactate was >5.0mmol/L. Our results suggest that the progression of MMVD results in accumulation of lactate within the bloodstream, which is likely attributable to the impaired peripheral tissue perfusion. In MMVD dogs, blood lactate may be used as a surrogate for cardiac remodeling, and an increased concentration is associated with a worse prognosis regarding the time to evolve into congestive heart failure.

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