Blood viscosity, red cell rigidity, and arterial blood pressure in patients with severe coronary occlusions or chest pains. Effect of submaximal exercise test.

2016 ◽  
Vol 1 (2) ◽  
pp. 121-134 ◽  
Author(s):  
L. Dintenfass
1992 ◽  
Vol 70 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Jean-François Landry ◽  
Jean-Pierre Després ◽  
Denis Prud'homme ◽  
Benoît Lamarche ◽  
Angelo Tremblay ◽  
...  

This study was undertaken (1) to examine the relation of plasma catecholamine and insulin levels to the blood pressure response during and after submaximal exercise, (2) to verify whether the blood pressure response to an epinephrine infusion is associated with the blood pressure response to a prolonged submaximal exercise, and (3) to study some potential correlates of the hypotensive effect of prolonged aerobic exercise. Nine normotensive young men (mean age 22.0 ± 1.4 years) were subjected to a 1-h epinephrine infusion protocol and a 1-h submaximal exercise test on a cycle ergometer. The two tests were performed 1 week apart. The physiological and hormonal responses observed during the submaximal exercise test were generally greater than those observed during the epinephrine infusion test. Blood pressure responses in both tests showed no significant association with changes in plasma insulin levels. Changes in plasma norepinephrine concentration were positively correlated with changes in systolic blood pressure during the submaximal exercise test but not during the epinephrine infusion. Results also showed that the blood pressure response to epinephrine infusion was not correlated with the blood pressure response to submaximal exercise. However, post-exercise and post-infusion systolic blood pressure responses (differences between "post-test" and "resting" values) were significantly associated (r = 0.81, p < 0.01). In addition, a significant hypotensive effect of submaximal exercise was observed for both systolic and diastolic blood pressure. However, the individual differences observed in the hypotensive effect of aerobic exercise appeared to be more related to variations in vascular sensitivity than to exercise-induced variations in plasma insulin and catecholamine levels, at least in this sample of healthy normotensive young men.Key words: blood pressure, exercise, catecholamines, insulin, epinephrine infusion.


2016 ◽  
Vol 41 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Katarzyna Szmigielska ◽  
Anna Szmigielska-Kapłon ◽  
Anna Jegier

The aim of the study was to determine arterial blood pressure response to exercise in young athletes. The study group comprised 711 young athletes (457 boys, 254 girls) aged 10 to 18 years (mean 13.41 ± 3.12 years) who had been training for an average of 7.62 ± 4.2 h per week for an average of 4.01 ± 2.5 years. Participants with elevated arterial blood pressure above the 90th percentile at rest were excluded from investigation. A symptom-limited, multistage exercise test to exhaustion was performed using a Monark cycle ergometer. Arterial blood pressure was measured with an aneroid manometer in the third minute of each stage of the test. Mean systolic arterial blood pressure during peak exercise was significantly higher in boys than in girls: 183.21 ± 27.97 mm Hg and 170.97 ± 21.4 mm Hg, respectively (p = 0.03). Multivariate linear regression analysis showed that age and workload had significant effects on arterial blood pressure during the test. Systolic arterial blood pressure during the exercise can be described with the following equations: boys, SBPex (mm Hg) = –1.92 × age (years) + 0.55 × workload (W) + 120.84; girls, SBPex (mm Hg) = –0.88 × age (years) + 0.48 × workload (W) + 111.22. The study results describe reference values of arterial blood pressure during the exercise test. The presented equations and figures can help to assess whether the arterial blood pressure at each stage of the exercise test exceeds the normal range or not.


2010 ◽  
Vol 299 (3) ◽  
pp. H863-H867 ◽  
Author(s):  
Beatriz Y. Salazar Vázquez ◽  
Judith Martini ◽  
Amy G. Tsai ◽  
Paul C. Johnson ◽  
Pedro Cabrales ◽  
...  

The hematocrit (Hct) of awake hamsters was lowered to 90% of baseline by isovolemic hemodilution using hamster plasma to determine the acute effect of small changes in Hct and blood viscosity on systemic hemodynamics. Mean arterial blood pressure increased, reaching a maximum of about 10% above baseline (8.6 ± 5.5 mmHg) when Hct decreased 8.4 ± 1.9% ( P < 0.005). Cardiac output increased continuously with hemodilution. These conditions were reached at ∼60 min after exchange transfusion and remained stationary for 1 h. Peripheral vascular resistance was approximately constant up to a decrease of Hct of about 10% and then fell continuously with lowering Hct. Vascular hindrance or vascular resistance independent of blood viscosity increased by about 20% and remained at this level up to an Hct decrease of 20%, indicating that the vasculature constricted with the lowered Hct. The results for the initial 2-h period are opposite but continuous with previous findings with small increases in Hct. In conclusion, limited acute anemic conditions increase mean arterial blood pressure during the initial period of 2 h, an effect that is quantitatively similar but opposite to the acute increase of Hct during the same period.


1997 ◽  
Vol 12 (3) ◽  
pp. 149-152 ◽  
Author(s):  
Linda A. Goodrum ◽  
Kenneth J. Moise, Jr. ◽  
George R. Saade ◽  
Michael A. Belfort ◽  
Nancy A. Ayres ◽  
...  

Nitric Oxide ◽  
2007 ◽  
Vol 16 (4) ◽  
pp. 448-456 ◽  
Author(s):  
Joseph M. Rifkind ◽  
Enika Nagababu ◽  
Efrat Barbiro-Michaely ◽  
Somasundaram Ramasamy ◽  
Ryszard M. Pluta ◽  
...  

Biorheology ◽  
2016 ◽  
Vol 53 (2) ◽  
pp. 93-107 ◽  
Author(s):  
Mark B. Plotnikov ◽  
Oleg I. Aliev ◽  
Alexey V. Nosarev ◽  
Alexander Y. Shamanaev ◽  
Anastasia V. Sidekhmenova ◽  
...  

1980 ◽  
Vol 8 (3) ◽  
pp. 117-123 ◽  
Author(s):  
Björn G. Jonsson ◽  
Irma Åstrand

A random sample ( n = 1 050) of the population of a region in central Sweden performed a submaximal exercise test on bicycle ergometers. The participants were men and women aged 18 to 65 taking part in the REBUS study 1969–71 (3). This paper deals with the partial relationship between heart rate at different rates of work and systolic blood pressure measured at rest (SBP) controlling the influence of other predictors of heart rate. It was found that the relationship was non-linear and that individuals with a relatively high SBP had a lower heart rate than individuals with lower SBP. The curvilinear relationship was more pronounced in women and grew stronger with increasing rate of work.


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