Clinical profile of early postnatal body weight changes in extremely low birth weight infants

2010 ◽  
Vol 3 (2) ◽  
pp. 95-101
Author(s):  
Rita Prasad Verma ◽  
Syed Shibli ◽  
Hai Fang
Keyword(s):  
Body Weight ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Clinical Profile ◽  
Extremely Low Birth Weight ◽  
Weight Changes ◽  
Low Birth Weight Infants ◽  
Body Weight Changes

Postnatal Weight Changes in Low Birth Weight Infants

PEDIATRICS ◽  
1987 ◽  
Vol 79 (5) ◽  
pp. 702-705
Author(s):  
Stanley G. Shaffer ◽  
Cheryl L. Quimiro ◽  
John V. Anderson ◽  
Robert T. Hall
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Weight Gain ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Considerable Variability ◽  
Weight Changes ◽  
Low Birth Weight Infants ◽  
Body Weight Changes ◽  
Weight Groups

Postnatal body weight changes were assessed in 385 surviving infants with birth weights of less than 2,500 g. Body weight was measured daily between birth and 45 days of age. Infants were grouped according to 100-g birth weight categories, and mean body weight changes for each group were compared. Initial postnatal weight loss occurred in each group and ranged between 7.9% and 14.6% of birth weight. Mean postnatal weight loss was greater in the lowest birth weight groups, but considerable variability was observed among individual infants. Duration of postnatal weight loss was similar among all birth weight groups. Weight gain usually began between four and six days of age, and the rate of weight gain expressed as grams per kilogram per day was similar in all birth weight groups.

Post-natal thyroid function in low birth weight infants; a longitudinal assessment of free thyroxine and thyroid hormone binding globulin

1985 ◽  
Vol 110 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Takeki Hirano ◽  
Jaideep Singh ◽  
Gopal Srinivasan ◽  
Rosita Pildes
Keyword(s):  
Body Weight ◽  
Birth Weight ◽  
Thyroid Hormone ◽  
Low Birth Weight ◽  
Free Thyroxine ◽  
Extremely Low Birth Weight ◽  
Longitudinal Assessment ◽  
Hormone Binding ◽  
Low Birth Weight Infants ◽  
Term Infants

Abstract. Because the concentrations of serum free thyroxine (FT4) and thyroid hormone binding globulin (TBG) have not been fully evaluated in preterm infants at the immediate post-natal period, we studied the longitudinal changes of serum FT4 and TBG, along with thyroxine (T4) and thyroid stimulating hormone (TSH), at birth (cord blood), 2 days, 1 week and 2 weeks of age in 7 infants with birth body weight ≦ 1000 g, 7 infants with body weight 1001 to 1350 g, 11 infants with body weight 1351 to 2499 g, and 11 full-term infants. Free T4 concentrations were measured by Corning Medical radio-immunoassay (RIA) kit. The infants with extremely low birth weight (ELBW) (body weight ≦ 1000 g) showed precipitous declines of total T4 and, to a lesser extent, of FT4 concentrations at 1 and 2 weeks of age. These post-natal T4 and FT4 decreases in ELBW neonates have not previously been reported. The clinical significance of this finding remains, speculative, but it may be due to metabolic or nutritional problems related to extreme prematurity itself. This study suggests that measurement of FT4 is a useful adjunct to the assessment of ELBW infants with wery low T4 values, if done between 1 to 2 weeks af age, and could be used as a primary hypothyroid screening tool instead of T4 measurements, provided that an FT4 assay is developed that uses the elute of blood spotted on filter paper.

scholarly journals Population pharmacokinetic analysis and dose regimen optimization in Japanese infants with an extremely low birth weight

2020 ◽  
pp. AAC.02523-20
Author(s):  
Hiroshi Sasano ◽  
Kanon Aoki ◽  
Ryutarou Arakawa ◽  
Kazuhiko Hanada
Keyword(s):  
Body Weight ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Dosage Regimen ◽  
Extremely Low Birth Weight ◽  
Pharmacokinetic Data ◽  
Optimal Dosage ◽  
Low Birth Weight Infants ◽  
Final Model ◽  
Optimal Dosage Regimen

Vancomycin is a synthetic antibiotic effective against gram-positive pathogens. Although the clinical applicability of vancomycin for infants has been increasing, the pharmacokinetic data of vancomycin in extremely low-birth-weight infants are limited. The aim of this study was to construct a population pharmacokinetics model for vancomycin in extremely low-birth-weight infants and establish an optimal dosage regimen. We enrolled children aged less than 1 yr with a birth weight of less than 1000 g and body weight at vancomycin prescription of less than 1500 g. Pharmacokinetic data from 19 patients were analyzed and a population pharmacokinetics model was developed using nonlinear mixed-effects modeling software. Goodness-of-fit plots, a nonparametric bootstrap analysis, and a prediction-corrected visual predictive check were employed to evaluate the final model. The dosage regimen was optimized based on the final model. The pharmacokinetic data fit a one-compartment model with first-order elimination, and body weight and estimated serum creatinine level were used as significant covariates. In a simulation using the final model, the optimal dosage regimen, especially when the serum creatinine level (>0.6 mg/dL) was high, was 5.0–7.5 mg/kg twice a day every 12 h; this was required to reduce the dosage compared with that in previous studies. The recommended doses based on the current target time-course concentration curves may not be appropriate for extremely low-birth-weight infants.

Arginine-Vasopressin in severe septic vs. non-septic shock in extremely low birth weight infants with acute renal failure

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
S Meyer ◽  
A Baghai ◽  
G Löffler ◽  
D Wurm ◽  
S Gottschling ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Arginine Vasopressin ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants

Arginine-Vasopressin in severe septic vs. non-septic shock in extremely low birth weight infants with acute renal failure

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
S Meyer ◽  
A Baghai ◽  
G Löffler ◽  
D Wurm ◽  
S Gottschling ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Arginine Vasopressin ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants

Hypernatremia in extremely low birth weight infants – case presentation

Perinatologia ◽  
2017 ◽  
Vol 4 (1) ◽  
pp. 172
Author(s):  
Veronica Cucoș ◽  
Adriana Dan
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Case Presentation
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