Faculty Opinions recommendation of Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants.

2017 ◽  
Author(s):  
Vineet Bhandari
Keyword(s):  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Respiratory Outcomes

scholarly journals Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants

2015 ◽  
Vol 169 (11) ◽  
pp. 1011 ◽  
Author(s):  
Erik A. Jensen ◽  
Sara B. DeMauro ◽  
Michael Kornhauser ◽  
Zubair H. Aghai ◽  
Jay S. Greenspan ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Respiratory Outcomes

scholarly journals The risk factors and progression of retinopathy of prematurity in extremely low birth weight infants

2021 ◽  
Vol 24 (3) ◽  
pp. 181-186
Author(s):  
Igor I. Dyumin ◽  
Elena A. Balakireva ◽  
Elena A. Yaroshevich ◽  
Aleksey I. Sevostyanov ◽  
Igor V. Nikolaenko
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Premature Babies ◽  
Ectopic Pregnancies

The number of premature babies, including those with extremely low birth weight (ELBW), is steadily growing every year. In surviving ELBW infants, retinopathy of prematurity (ROP) more often develops, which has a more severe course, depending not only on the degree of immaturity and somatic burden of premature babies but also on the quality of nursing. The aim of this work is to determine the risk factors for ROP progression in profoundly premature ELBW infants to optimize the tactics of their treatment. Materials and methods. We studied the case histories of 155 surviving premature ELBW infants with ROP of various stages treated in perinatal centres of the Belgorod region in 2014-2019. Results. In premature ELBW infants, ROP of varying severity was found to be diagnosed in 90% of cases. The anamnesis of the mothers of the examined patients with moderate and severe ROP was dominated by unfavorable preceding pregnancies (miscarriages, silent miscarriage and ectopic pregnancies, medical abortions).The need for preterm infants in mechanical ventilation was established to depend on the severity of ROP and the duration of mechanical ventilation (p < 0.05). Frequent, not always justified red blood transfusions leading to the replacement of fetal haemoglobin with adult haemoglobin are also essential factors in ROP progression.

scholarly journals Ventilatory management in extremely low birth weight infants

2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Shaun Morris ◽  
Karen Choong
Keyword(s):  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Extremely Low Birth Weight ◽  
High Frequency Ventilation ◽  
Low Birth Weight Infants ◽  
Ventilator Induced Lung Injury ◽  
Frequency Ventilation

The improvement in survival in premature infants associated with the evolution of mechanical ventilation has been accompanied by an increase in ventilator induced lung injury. High frequency ventilation has been shown to reduce the incidence of ventilator induced lung injury and hence chronic lung disease in the very low birth weight infant. The evolution in understanding how to best use high frequency ventilation in this population has prompted us to ask whether similar strategies to optimize lung volumes on conventional mechanical ventilation can minimize chronic lung disease in the neonate. We retrospectively reviewed the medical charts of 51 extremely low birth weight infants born in Kingston, Ontario in two epochs, 1990 to 1991 and 1999 to 2000, for ventilatory strategy and outcome. From our review, it is clear that surfactant therapy rapidly changes lung mechanics by improving pulmonary compliance and that lung damage may result if there are not changes in the ventilatory management to reflect the altered compliance. Early ventilation strategies during the apparently stable "honeymoon period" in a patient with respiratory distress syndrome (RDS) has significant implications on long term morbidity. In the era prior to the use of surfactant, 30% of infants died and 40% developed chronic lung disease (CLD). Immediately following the use of surfactant, mortality was reduced to 18%, however, the incidence of CLD increased to 78%. In the most recent era, following 10 years of experience with surfactant and mechanical ventilation, morbidity was 17% and CLD 21%. This study demonstrates that a particularly crucial time is in the immediate period following surfactant administration. The use of lower peak inspiratory pressure (PIP) and mean airway pressure (MAP) over the first 24 hours and an increase in the use of synchronous intermittent mandatory ventilation (SIMV) was associated with an improved outcome. The challenge remaining is to determine how to best utilize a conventional mode of ventilation to best optimize lung volume and protect the immature lung.

Prophylactic Indomethacin Worsens Short-Term Respiratory Outcomes in Extremely Low-Birth-Weight Infants

2013 ◽  
Vol 31 (01) ◽  
pp. 061-068
Author(s):  
Dipayan Chaudhuri ◽  
Brian Li ◽  
Sandesh Shivananda ◽  
Sourabh Dutta ◽  
Tapas Mondal
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
Short Term ◽  
Low Birth Weight Infants ◽  
Respiratory Outcomes

Factors associated with extubation failure in very low birth weight infants: a cohort study in the northeast Brazil

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Raphaela Farias Teixeira ◽  
Cinthia Maria Costa ◽  
Catarina Maria de Abreu ◽  
Cicero Amsterdan Lessa ◽  
Aline Carla Carvalho ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cohort Study ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Length Of Hospital Stay ◽  
Extubation Failure ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Vlbw Infants ◽  
Factors Associated

AbstractObjectivesIdentifying and understanding the main risk factors associated with extubation failure of very low birthweight (VLBW) infants in different populations can subsequently help in establishing better criteria while taking decision of extubation. The aim of the study was to identify factors associated with extubation failure in VLBW infants.MethodsA cohort study of VLBW infants who underwent their first extubation between April 2018 and December 2019 in a Neonatal Intensive Care Unit, Alagoas, Brazil, were included in this study. Extubation failure was defined as reintubation within seven days of extubation. Relative risks of predictive variables different between the extubation success group (ES) and extubation failure group (EF) were estimated with a robust Poisson regression model.ResultsOut of the 112 infants included, 26 (23%) cases exhibited extubation failure. Extremely low birth weight (RR 2.55, 95% CI 1.07, 6.06), mechanical ventilation duration for first extubation greater than seven days (RR 2.66, 95% CI 1.10, 6.45), vaginal delivery (RR 2.07, 95% CI 1.03, 4.18) and maternal chorioamnionitis (RR 4.89, 95% CI 1.26–18.98) remained independently associated with extubation failure. EF had a significant greater need for respiratory support, longer oxygen therapy duration, more bronchopulmonary dysplasia (BPD) and longer length of hospital stay, even when adjusted for confounding variables.ConclusionsExtremely low birth weight infants needing mechanical ventilation, wherein the duration for first extubation was longer than seven days, with vaginal delivery and maternal chorioamnionitis failed more frequently at the first attempt of extubation. And this failure increased the risk of BPD and the length of hospital stay.

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