scholarly journals Diffusion tensor imaging predicts the outcome of constraint-induced movement therapy in chronic infarction patients with hemiplegia: A pilot study

2013 ◽  
Vol 31 (4) ◽  
pp. 387-396 ◽  
Author(s):  
Kohei Marumoto ◽  
Tetsuo Koyama ◽  
Masashi Hosomi ◽  
Takashi Takebayashi ◽  
Keisuke Hanada ◽  
...  
2011 ◽  
Vol 71 ◽  
pp. e251
Author(s):  
Kohei Marumoto ◽  
Masashi Hosomi ◽  
Tetsuo Koyama ◽  
Keiko Furukawa ◽  
Norihiko Kodama ◽  
...  

2012 ◽  
Vol 67 (6) ◽  
pp. 370-376 ◽  
Author(s):  
Cristina Granziera ◽  
Hakan Ay ◽  
Susan P. Koniak ◽  
Gunnar Krueger ◽  
A. Gregory Sorensen

ASN NEURO ◽  
2018 ◽  
Vol 10 ◽  
pp. 175909141775380 ◽  
Author(s):  
Angela M. Muller ◽  
Naznin Virji-Babul

Sports-related concussion in youth is a major public health issue. Evaluating the diffuse and often subtle changes in structure and function that occur in the brain, particularly in this population, remains a significant challenge. The goal of this pilot study was to evaluate the relationship between the intrinsic dynamics of the brain using resting-state functional magnetic resonance imaging (rs-fMRI) and relate these findings to structural brain correlates from diffusion tensor imaging in a group of adolescents with sports-related concussions ( n = 6) and a group of healthy adolescent athletes ( n = 6). We analyzed rs-fMRI data using a sliding windows approach and related the functional findings to structural brain correlates by applying graph theory analysis to the diffusion tensor imaging data. Within the resting-state condition, we extracted three separate brain states in both groups. Our analysis revealed that the brain dynamics in healthy adolescents was characterized by a dynamic pattern, shifting equally between three brain states; however, in adolescents with concussion, the pattern was more static with a longer time spent in one brain state. Importantly, this lack of dynamic flexibility in the concussed group was associated with increased nodal strength in the left middle frontal gyrus, suggesting reorganization in a region related to attention. This preliminary report shows that both the intrinsic brain dynamics and structural organization are altered in networks related to attention in adolescents with concussion. This first report in adolescents will be used to inform future studies in a larger cohort.


2019 ◽  
Vol 34 (10) ◽  
pp. 556-566 ◽  
Author(s):  
Gwendolyn J. Gerner ◽  
Eric I. Newman ◽  
V. Joanna Burton ◽  
Brenton Roman ◽  
Elizabeth A. Cristofalo ◽  
...  

Aim: Hypoxic-ischemic encephalopathy is associated with damage to deep gray matter; however, white matter involvement has become recognized. This study explored differences between patients and clinical controls on diffusion tensor imaging, and relationships between diffusion tensor imaging and neurodevelopmental outcomes. Method: Diffusion tensor imaging was obtained for 31 neonates after hypoxic-ischemic encephalopathy treated with therapeutic hypothermia and 10 clinical controls. A subgroup of patients with hypoxic-ischemic encephalopathy (n = 14) had neurodevelopmental outcomes correlated with diffusion tensor imaging scalars. Results: Group differences in diffusion tensor imaging scalars were observed in the putamen, anterior and posterior centrum semiovale, and the splenium of the corpus callosum. Differences in these regions of interest were correlated with neurodevelopmental outcomes between ages 20 and 32 months. Conclusion: Therapeutic hypothermia may not be a complete intervention for hypoxic-ischemic encephalopathy, as neonatal white matter changes may continue to be evident, but further research is warranted. Patterns of white matter change on neonatal diffusion tensor imaging correlated with neurodevelopmental outcomes in this exploratory pilot study.


2009 ◽  
Vol 27 (6) ◽  
pp. 675-682 ◽  
Author(s):  
Anne Barzel ◽  
Joachim Liepert ◽  
Kerstin Haevernick ◽  
Marion Eisele ◽  
Gesche Ketels ◽  
...  

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