scholarly journals Thoracic Ganglion

2020 ◽  
Author(s):  
Keyword(s):  

2011 ◽  
Vol 86 (3) ◽  
pp. 451-456 ◽  
Author(s):  
Nelson Wolosker ◽  
José Ribas Milanez de Campos ◽  
Paulo Kauffman ◽  
Marco Antonio Munia ◽  
Samantha Neves ◽  
...  

BACKGROUND: Facial hyperhidrosis is a disease that may lead patients to serious emotional disturbances. Video-assisted thoracic sympathectomy provides excellent resolution of facial hyperhidrosis, but is associated with certain complications. The most frequent and important complication is compensatory hyperhidrosis. Especially in patients who have undergone resection of the second thoracic ganglion, the risk of severe compensatory hyperhidrosis is higher, which may cause dissatisfaction with the procedure. OBJECTIVE: The aim of this study was to evaluate the efficacy of the use of low doses of oxybutynin in treating facial hyperhidrosis as well as the level of patient satisfaction with its use. METHODS: 25 patients with facial hyperhidrosis were treated with oxybutynin. The patients underwent 2 evaluations: before and after treatment. These evaluations were used to assess the patients' clinical improvement and quality of life. RESULTS: We observed that more than 75% of the patients evolved with an improvement in facial hyperhidrosis, and 52% of them presented a great improvement. CONCLUSION: Treatment of facial hyperhidrosis with oxybutynin is a good alternative to sympathectomy, since it presents good results and improves quality of life, in addition to not exposing patients to the risk of experiencing the side effects of sympathectomy



2013 ◽  
Vol 53 (5) ◽  
pp. 309 ◽  
Author(s):  
Burak Kazanci ◽  
Ozkan Tehli ◽  
Erhan Türkoglu ◽  
Bulent Guclu


2003 ◽  
Vol 308 (3) ◽  
pp. 535-544 ◽  
Author(s):  
Jurgen Huybrechts ◽  
Michael P Nusbaum ◽  
Luc Vanden Bosch ◽  
Geert Baggerman ◽  
Arnold De Loof ◽  
...  


1969 ◽  
Vol 50 (3) ◽  
pp. 615-627
Author(s):  
M. E. SPIRA ◽  
I. PARNAS ◽  
F. BERGMANN

1. Stimulation of the connectives between the suboesophageal and prothoracic ganglia of the American cockroach induced ipsilateral descending spikes in the abdominal giant axons with an average delay of 0·6 msec, per thoracic ganglion. 2. Nicotine at 5 µg./ml. had no effect on conduction in the abdomen but blocked ascending responses sequentially at the 6th abdominal ganglion then at the levels of T1; T2, and T3. 3. Simultaneous descending and ascending impulses resulted in mutual extinction along the nerve cord with the point of collision depending on the interval between stimuli. 4. It is suggested that a common pathway subserves ascending and descending giant impulses and models for bi-directional conduction are discussed.



1963 ◽  
Vol 54 (2) ◽  
pp. 189-197 ◽  
Author(s):  
K. A. Lord ◽  
Frances M. Molloy ◽  
C. Potter

The nerve sheath of the thoracic ganglion of the house-fly (Musca domestica L.) is readily permeable to diazoxon but is impermeable to acetyl choline and acetyl thiocholine. Acetone and other lipoidal solvents, but not formaldehyde, were found to destroy the barrier to entry of the substrates, acetyl choline and acetyl thiocholine, and it is inferred that the barrier is lipoidal. At − 16°C., acetone does not destroy the cholinesterase of the ganglion.Cholinesterase associated with the ganglion could be divided into three regions which showed different inhibition characteristics: (a) ‘ superficial ’ enzyme outside the nerve sheath, inhibited by 3·3 × 10−8M diazoxon; (b) ‘ peripheral ’ enzyme in the cellular region of the ganglion, inhibited by 3·3 × 10−8M and 3·3 × 10−9M diazoxon; (c) ‘ central ’ enzyme in the synaptic area, inhibited by not less than 3·3 × 10−7M diazoxon. Using inhibition of cholinesterase as an indicator of penetration, no difference in permeability was found between the ganglia of the susceptible and resistant strains. No difference was found in the inhibition of cholinesterase by diazoxon in the ganglia of susceptible and resistant strains.It is concluded from this and previous work that if inhibition of cholinesterase of the nervous system is the cause of death there are no differences between the ganglia of the susceptible and resistant strains which affect resistance; and, furthermore, that inhibition of cholinesterase in the thoracic ganglion is unlikely to be the cause of death.





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