scholarly journals Continuous Venovenous Hemodialysis

2020 ◽  
Author(s):  
Keyword(s):  
Continuous Venovenous Hemodialysis

Indications for Dialysis in Acute Kidney Injury

2020 ◽  
Author(s):  
Ankit Patel ◽  
Kenneth B Christopher
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
High Efficiency ◽  
Kidney Injury ◽  
Intermittent Hemodialysis ◽  
Continuous Venovenous Hemofiltration ◽  
Continuous Venovenous Hemodialysis ◽  
Low Efficiency ◽  
The Impact

Renal replacement therapy (RRT) can be used to support patient’s kidney function in cases of acute kidney injury (AKI). However, timing, modality, and dosing of RRT continue to remain in question. Recent studies have begun to provide data to help guide clinicians on when to initiate RRT, what form of RRT to use ranging from continuous venovenous hemofiltration (VVH) to intermittent hemodialysis, and the impact of high versus low-intensity dosing. Additionally, the risks associated with temporary vascular access with regard to thrombosis and infection, the impact of high efficiency and flux versus low efficiency and flux membranes, and options for anticoagulation in RRT for AKI are also discussed. This review contains 75 references.  Key words: acute kidney injury, chronic kidney disease, continuous venovenous hemofiltration, continuous venovenous hemodialysis, renal replacement therapy, venovenous hemofiltration, 

scholarly journals Initial Vancomycin Dosing Recommendations for Critically Ill Patients Undergoing Continuous Venovenous Hemodialysis

2010 ◽  
Vol 63 (3) ◽  
Author(s):  
Sandra A N Walker ◽  
Lyndsay M Van de Vijsel ◽  
Scott E Walker ◽  
Sharon Yamashita ◽  
Andrew Simor ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Continuous Venovenous Hemodialysis

CONTINUOUS VENOVENOUS HEMODIALYSIS (CVVHD) CLEARANCE OF CEFTRIAXONE

ASAIO Journal ◽  
1996 ◽  
Vol 42 (2) ◽  
pp. 90 ◽  
Author(s):  
G. R. Matzke ◽  
R. F. Frye ◽  
M. Joy ◽  
P. Palevsky
Keyword(s):  
Continuous Venovenous Hemodialysis

Continuous venovenous hemodialysis

1994 ◽  
Vol 3 (2) ◽  
pp. 92-99 ◽  
Author(s):  
BL Strohschein ◽  
DM Caruso ◽  
KA Greene
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Hemodynamic Instability ◽  
Cerebellar Hemorrhage ◽  
Renal Replacement Therapies ◽  
Surgical Evacuation ◽  
Fluid Shifts ◽  
Continuous Venovenous Hemodialysis ◽  
Dialysis Disequilibrium Syndrome ◽  
Continuous Hemodialysis

Hemodialysis and peritoneal dialysis are the main renal replacement therapies for patients with acute renal failure. These patients are often unable to tolerate drastic fluid shifts and other complications of conventional dialysis. Continuous hemodialysis, however, provides protection from the hemodynamic consequences and osmotic stressors of conventional dialysis and is rapidly becoming the treatment of choice for critically ill patients. We present a case in which a patient with a spontaneous cerebellar hemorrhage developed acute renal failure. Surgical evacuation was not an option. Clinical management included the use of continuous venovenous hemodialysis, which is described in the setting of a patient with a posterior fossa mass. The risks of anticoagulation, hemodynamic instability, and development of dialysis disequilibrium syndrome are discussed.

Pharmacokinetics and dosing estimation of meropenem in Japanese patients receiving continuous venovenous hemodialysis

2015 ◽  
Vol 21 (6) ◽  
pp. 476-478 ◽  
Author(s):  
Shinji Kawano ◽  
Kazuaki Matsumoto ◽  
Ryohei Hara ◽  
Yuko Kuroda ◽  
Kazuro Ikawa ◽  
...  
Keyword(s):  
Japanese Patients ◽  
Continuous Venovenous Hemodialysis

Clearance of Levofloxacin by an in Vitro Model of Continuous Venovenous Hemodialysis (CVVHD)

2007 ◽  
Vol 30 (10) ◽  
pp. 889-895 ◽  
Author(s):  
S. Siewert ◽  
B. Drewelow ◽  
S.C. Mueller
Keyword(s):  
In Vitro Model ◽  
Urea Clearance ◽  
Flow Rates ◽  
Dialysate Flow ◽  
Dialysate Flow Rate ◽  
Continuous Venovenous Hemodialysis ◽  
Vitro Model ◽  
Positive Correlations

Information about the elimination and the adequate dosing of levofloxacin during renal replacement therapy is scarce. The aim of this study was to characterize in vitro the elimination of levofloxacin during continuous venovenous hemodialysis (CVVHD) and to investigate whether the CVVHD clearances of creatinine and urea are correlated with the levofloxacin clearance in order to facilitate dosage adjustments. An in vitro model of CVVHD was established using five dialyzer membranes at varying dialysate flow rates applied in the clinical setting (8, 16, 25, 33 and 41 ml/min). Plasma and dialysate samples were drawn for determination of levofloxacin, creatinine and urea concentrations to evaluate clearances by CVVHD. During CVVHD, the clearance of levofloxacin varied between 9.02 and 33.30 ml/min, depending on the chosen setup. Positive correlations (p<0.001) were received for: dialysate flow rate (QD) and creatinine/urea clearances (R>0.93); QD and levofloxacin clearance (R 0.59–0.71); levofloxacin and creatinine clearance (R 0.69–0.75); and levofloxacin and urea clearance (R 0.56–0.75) as well. When dosing critically ill patients, therefore, extracorporeal as well as total clearance of levofloxacin should be considered.

scholarly journals Determinants of Ceftazidime Clearance by Continuous Venovenous Hemofiltration and Continuous Venovenous Hemodialysis

2000 ◽  
Vol 44 (6) ◽  
pp. 1639-1644 ◽  
Author(s):  
Gary R. Matzke ◽  
Reginald F. Frye ◽  
Melanie S. Joy ◽  
Paul M. Palevsky
Keyword(s):  
Repeated Measures ◽  
High Performance ◽  
Mixed Model ◽  
Random Effect ◽  
Quantitative Information ◽  
Continuous Venovenous Hemofiltration ◽  
Linear Relationships ◽  
Repeated Measures Analysis ◽  
Continuous Venovenous Hemodialysis ◽  
Dosing Strategies

ABSTRACT Although several dosage adjustment regimens have been proposed, there is little quantitative information to guide the initiation of ceftazidime therapy in patients who are receiving continuous renal replacement therapy. To determine the clearance of ceftazidime by continuous venovenous hemofiltration (CVVH) and continuous venovenous hemodialysis (CVVHD), we performed controlled clearance studies with stable hemodialysis patients with three hemofilters: a 0.6-m2 acrylonitrile copolymer (AN69; Hospal) filter, a 2.1-m2 polymethylmethacrylate filter (PMMA; Toray) filter and a 0.65-m2 polysulfone (PS; Fresenius) filter. Subjects received 1,000 mg of ceftazidime intravenously prior to the start of a clearance study. The concentration of ceftazidime in multiple plasma and dialysate or ultrafiltrate samples was determined by high-performance liquid chromatography. The diffusional clearances (CIdiffusion) and sieving coefficients of ceftazidime were compared by a mixed-model repeated-measures analysis of variance with filter and blood, dialysate inflow, or ultrafiltration rate as the main effect and the patient as a random effect. The fraction of ceftazidime bound to plasma proteins was 17% ± 7% (range, 10 to 25%). The clearances of ceftazidime, urea, and creatinine by CVVHD were essentially constant at blood flow rates of 75 to 250 ml/min for all three filters. Significant linear relationships (P < 0.0001) were observed between CIdiffusion of ceftazidime and clearance of urea for all three filters: AN69 (slope = 0.83), PMMA (slope = 0.89), and PS (slope = 1.03). Ceftazidime clearance was membrane independent during CVVH and CVVHD. CVVH and CVVHD can significantly augment the clearance of ceftazidime. Dosing strategies for initiation of ceftazidime therapy in patients receiving CVVH and CVVHD are proposed.

scholarly journals A fractional dialysate collection method to estimate solute removal in continuous venovenous hemodialysis

2000 ◽  
Vol 58 (6) ◽  
pp. 2579-2584 ◽  
Author(s):  
Nigel S. Kanagasundaram ◽  
A. Brett Larive ◽  
Emil P. Paganini
Keyword(s):  
Collection Method ◽  
Continuous Venovenous Hemodialysis
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