Wedge Biopsy | ScienceGate

Abstract Context.—Frozen section of lung tissue is performed to guide the surgeon in subsequent therapy. Design.—Practical experience in frozen section of the lung was reviewed in the medical literature and from the records of several academic hospitals. Results.—Most frozen sections of the lung are performed for evaluation of a solitary nodule, a mass, or the surgical margins of a resection. Frozen section may also be used to assess the adequacy of a lung wedge biopsy taken for later diagnosis of a condition. Conclusion.—The pathologic evaluation of intraoperative pulmonary lesions is indicated for the differential diagnosis of pulmonary nodules and masses, both neoplastic and nonneoplastic, surgical resection margins, and mediastinal lymph nodes. The most worrisome pitfalls involve differentiating benign reactive atypia from malignancy on frozen section.

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Benign Myoepithelioma of the Lung

Archives of Pathology & Laboratory Medicine ◽

10.5858/2001-125-1494-bmotl ◽

2001 ◽

Vol 125 (11) ◽

pp. 1494-1496

Author(s):

Ravindra Veeramachaneni ◽

Janis Gulick ◽

Ari O. Halldorsson ◽

Thanh T. Van ◽

Ping L. Zhang ◽

...

Keyword(s):

Positron Emission Tomography ◽

Smooth Muscle ◽

Smooth Muscle Actin ◽

Emission Tomography ◽

Muscle Actin ◽

Computed Tomographic ◽

Spindle Cells ◽

Positron Emission ◽

Computed Tomographic Scan ◽

Wedge Biopsy

Abstract This report describes a benign myoepithelioma of the lung that occurred in a 60-year-old woman. The patient had experienced hoarseness for 6 weeks, and a computed tomographic scan showed a nodule of approximately 2 cm in diameter at the peripheral portion of her right upper lung. Positron emission tomography showed no uptake of F-18 fluorodeoxyglucose in the nodule. Wedge biopsy of the lesion showed benign spindle cells arranged in a whorled pattern. The cells were positive for both cytokeratin and smooth muscle actin, which corresponded to the presence of tonofilaments and myofilaments that were identified ultrastructurally. The features of the present case of benign myoepithelioma that differ from features of previously reported benign and malignant cases of myoepithelioma in the lung are discussed in the report.

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Recurrent leiomyoma of the vulva mimicking peripheral nerve sheath tumour

BMJ Case Reports ◽

10.1136/bcr-2019-232065 ◽

2019 ◽

Vol 12 (12) ◽

pp. e232065

Author(s):

Keerthana Kothandaraman ◽

Gowri Dorairajan ◽

Murali Subbaiah ◽

LN Dorairajan ◽

Bhawana A Badhe ◽

...

Keyword(s):

Smooth Muscle ◽

Postmenopausal Woman ◽

Peripheral Nerve ◽

Smooth Muscle Actin ◽

Muscle Actin ◽

Soft Tissue Tumours ◽

Nerve Sheath Tumour ◽

Nerve Sheath ◽

Wedge Biopsy ◽

Peripheral Nerve Sheath Tumour

Leiomyoma, a benign monoclonal tumour, is very rarely found in extrauterine sites, especially in the vulval region. Histopathology of the soft tissue tumours affecting this region is similar and immunohistochemistry (IHC) may be essential to confirm the diagnosis. We report a case of a 63-year-old postmenopausal woman who presented with a recurrent vulval mass involving the clitoris and left labia majora with suspected urethral involvement. Although the wedge biopsy was reported as peripheral nerve sheath tumour, staining with smooth muscle actin clinched the diagnosis of leiomyoma, highlighting the importance of IHC for diagnosis.

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KIDNEY DONOR BIOPSY; STANDARDIZING TECHNIQUE USING A WEDGE BIOPSY.

Transplantation Journal ◽

10.1097/00007890-200607152-02598 ◽

2006 ◽

Vol 82 (Suppl 2) ◽

pp. 923

Author(s):

&NA;

Keyword(s):

Kidney Donor ◽

Wedge Biopsy ◽

Donor Biopsy

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Laparoscopic vs. Open Wedge Biopsy of the Liver

Journal of Laparoendoscopic Surgery ◽

10.1089/lps.1993.3.325 ◽

1993 ◽

Vol 3 (4) ◽

pp. 325-329 ◽

Cited By ~ 15

Author(s):

ROBERT E. FALCONE ◽

STEVEN R. WANAMAKER ◽

FRANCIS BARNES ◽

CHERYL G. BAXTER ◽

STEVEN A. SANTANELLO

Keyword(s):

Open Wedge ◽

Wedge Biopsy

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Pleuroparenchymal fibroelastosis presenting with pneumothorax

SAGE Open Medical Case Reports ◽

10.1177/2050313x18762853 ◽

2018 ◽

Vol 6 ◽

pp. 2050313X1876285 ◽

Cited By ~ 1

Author(s):

Yen-Yu Lin ◽

Wen-Hu Hsu ◽

Mei-Han Wu ◽

Teh-Ying Chou

Keyword(s):

Interstitial Pneumonia ◽

Progressive Disease ◽

Inflammatory Cell ◽

Clinical Presentation ◽

Usual Interstitial Pneumonia ◽

Distinct Type ◽

Pleuroparenchymal Fibroelastosis ◽

Biopsy Specimens ◽

Wedge Biopsy ◽

Pleural Involvement

A 47-year-old woman presented with spontaneous right side pneumothorax. Image studies showed consolidations and reticular opacities involving the pleural and subpleural regions of bilateral lungs. Wedge biopsy specimens of right upper, middle and lower lobes showed fibrosis of the visceral pleura and subpleural area in all three lobes, more significant in the upper lobe. Elastic Van Gieson stain showed a pattern of alveolar septal elastosis with intra-alveolar fibrosis. The clinical presentation and pathological findings are compatible with pleuroparenchymal fibroelastosis, a rare and distinct type of interstitial lung disease. This entity is different from usual interstitial pneumonia by its relationship to pleura, upper lobe predominance and temporal homogeneity. It is different from non-specific interstitial pneumonia by its pleural involvement and scanty inflammatory cell infiltration. Pleuroparenchymal fibroelastosis is a slowly progressive disease; about half of the patients die in 10 years. No curative treatment is available at present time.

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The Perfused Human Liver Wedge Biopsy: A New In Vitro Model for Morphological and Functional Studies

Hepatology ◽

10.1002/hep.1840020406 ◽

2007 ◽

Vol 2 (4) ◽

pp. 426S-432S ◽

Cited By ~ 5

Author(s):

Susan J. Burwen ◽

Albert L. Jones ◽

Ira S. Goldman ◽

Lawrence W. Way ◽

Sussan Dejbakhsh

Keyword(s):

Human Liver ◽

In Vitro Model ◽

Functional Studies ◽

Vitro Model ◽

Wedge Biopsy

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Wedge Biopsy of Liver

10.32388/s4280g ◽

2020 ◽

Author(s):

Keyword(s):

Wedge Biopsy

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Spontaneous cholecystocutaneous fistula: empirically treated for a missed diagnosis, managed by laparoscopy

BMJ Case Reports ◽

10.1136/bcr-2018-228138 ◽

2019 ◽

Vol 12 (2) ◽

pp. e228138 ◽

Cited By ~ 2

Author(s):

Manjunath Maruti Pol ◽

Surabhi Vyas ◽

Priyanka Singh ◽

Yashwant Singh Rathore

Keyword(s):

Anterior Abdominal Wall ◽

Health Centre ◽

Sinus Tract ◽

Postoperative Recovery ◽

Primary Health Centre ◽

Primary Health ◽

Missed Diagnosis ◽

Normal Ultrasound ◽

The Right ◽

Wedge Biopsy

A 70-year-old woman was referred to our hospital from primary health centre with complaints of pain in the abdomen, swelling and discharging sinus in the right hypochondrium since 2 years. She had received anti-tubercular treatment for 18 months as the wedge biopsy of the sinus tract suggested granulomatous lesion. As the symptoms did not subside she was referred to our hospital. Her blood investigation reports at our hospital were normal. Ultrasound of the abdomen suggested cholelithiasis with normal common bile duct. CT fistulogram findings were diagnostic of cholecystocutaneous fistula (CCCF). She underwent laparoscopic cholecystectomy and excision of the sinus tract. Postoperative recovery was uneventful. Indiscriminate usage of anti-tubercular drugs should be discouraged and possibility of CCCF should be considered in patients presenting with discharging sinus in the anterior abdominal wall. CT fistulogram is helpful in making diagnosis of CCCF. Cholecystectomy with excision of the sinus tract is the treatment of choice.

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