scholarly journals Traumatic versus non traumatic spinal cord injury: Characteristics and functional outcome in a Tunisian rehabilitation centre

2018 ◽  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Functional Outcome ◽  
Considerable Proportion ◽  
Traumatic Spinal Cord Injury ◽  
Physical Medicine ◽  
Injury Characteristics ◽  
Injury Group ◽  
Cord Injury

Background: Understanding of the underlying mechanisms of Spinal cord injury (SCI) would help in the development of treatment strategies and enhance neurological recovery. Aim: The aim of this study was to describe clinical and demographic data of SCI in a physical medicine department and to compare neurological and functional outcome in Traumatic Spinal Cord Injury group (TSCI) and Non Traumatic Spinal Cord Injury group (NTSCI) during two years of follow up. Materials and methods: This study was conducted in a physical medicine and rehabilitation department of a tertiary hospital (January 2008-December 2014). Medical records of 177 patients with spinal cord injury (SCI) were reviewed. Two groups were defined: traumatic (TSCI) and non-traumatic (NTSCI) spinal cord injury. Characteristics and functional outcome were analyzed and compared. Results: Patients of NT group were significantly older. Most of injuries in both groups had a cervical level. ASIA scale scores and MIF scales were significantly higher in NT group at admission and after two years of follow up. The impairment was more remarkable in this group. Conclusions: Our study suggests that non traumatic SCI represent a considerable proportion of SCI rehabilitation admissions. Although different characteristics and injury patterns, functional outcomes maybe comparable to traumatic SCI. Key words: spinal cord injury, epidemiology, etiology, rehabilitation

scholarly journals A multicentre follow-up of clinical aspects of traumatic spinal cord injury

Spinal Cord ◽  
2006 ◽  
Vol 45 (6) ◽  
pp. 404-410 ◽  
Author(s):  
M C Pagliacci ◽  
◽  
M Franceschini ◽  
B Di Clemente ◽  
M Agosti ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Clinical Aspects ◽  
Traumatic Spinal Cord Injury ◽  
Cord Injury

scholarly journals A Clinical Prediction Model for Long-Term Functional Outcome after Traumatic Spinal Cord Injury Based on Acute Clinical and Imaging Factors

2012 ◽  
Vol 29 (13) ◽  
pp. 2263-2271 ◽  
Author(s):  
Jefferson R. Wilson ◽  
Robert G. Grossman ◽  
Ralph F. Frankowski ◽  
Alexander Kiss ◽  
Aileen M. Davis ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Prediction Model ◽  
Functional Outcome ◽  
Traumatic Spinal Cord Injury ◽  
Clinical Prediction ◽  
Clinical Prediction Model ◽  
Cord Injury

Late neurological changes following traumatic spinal cord injury

1988 ◽  
Vol 69 (3) ◽  
pp. 399-402 ◽  
Author(s):  
Joseph M. Piepmeier ◽  
N. Ross Jenkins
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Spinal Cord Injuries ◽  
Neurological Status ◽  
Neurological Function ◽  
Traumatic Spinal Cord Injury ◽  
Content Type ◽  
Cord Injury ◽  
Fine Print

✓ Sixty-nine patients with traumatic spinal cord injuries were evaluated for changes in their functional neurological status at discharge from the hospital, and at 1 year, 3 years, and 5+ years following injury. The neurological examinations were used to classify patients' spinal cord injury according to the Frankel scale. This analysis revealed that the majority of improvement in neurological function occurred within the 1st year following injury; however, changes in the patients' status continued for many years. Follow-up examinations at an average of 3 years postinjury revealed that 23.3% of the patients continued to improve, whereas 7.1% had deteriorated compared to their status at 1 year. An examination at an average of 5+ years demonstrated further improvement in 12.5%, with 5.0% showing deterioration compared to the examinations at 3 years. These results demonstrate that, in patients with spinal trauma, significant changes in neurological function continue for many years.

scholarly journals Neurogenic bladder in patients with traumatic spinal cord injury: treatment and follow-up

Spinal Cord ◽  
2014 ◽  
Vol 52 (6) ◽  
pp. 462-467 ◽  
Author(s):  
N Yıldız ◽  
◽  
Y Akkoç ◽  
B Erhan ◽  
B Gündüz ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neurogenic Bladder ◽  
Traumatic Spinal Cord Injury ◽  
Cord Injury ◽  
Injury Treatment

A prediction model of functional outcome at 6 months using clinical findings of a person with traumatic spinal cord injury at 1 month after injury

Spinal Cord ◽  
2020 ◽  
Vol 58 (11) ◽  
pp. 1158-1165
Author(s):  
Yuto Ariji ◽  
Tetsuo Hayashi ◽  
Ryosuke Ideta ◽  
Ryuichiro Koga ◽  
Satoshi Murai ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Prediction Model ◽  
Functional Outcome ◽  
Clinical Findings ◽  
Traumatic Spinal Cord Injury ◽  
Cord Injury

scholarly journals Effects of Growth Hormone Treatment and Rehabilitation in Incomplete Chronic Traumatic Spinal Cord Injury: Insight from Proteome Analysis

2020 ◽  
Vol 10 (4) ◽  
pp. 183
Author(s):  
Tatiana Martin-Rojas ◽  
Tamara Sastre-Oliva ◽  
Ana Esclarín-Ruz ◽  
Felix Gil-Dones ◽  
Laura Mourino-Alvarez ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Growth Hormone ◽  
Spinal Cord Injury ◽  
Functional Outcome ◽  
Combined Treatment ◽  
Traumatic Spinal Cord Injury ◽  
Motor Score ◽  
Gh Treatment ◽  
Rehabilitation Treatment ◽  
Cord Injury

Despite promising advances in the medical management of spinal cord injury (SCI), there is still no available effective therapy to repair the neurological damage in patients who experience this life-transforming condition. Recently, we performed a phase II/III placebo-controlled randomized trial of safety and efficacy of growth hormone (GH) treatment in incomplete chronic traumatic spinal cord injury. The main findings were that the combined treatment of GH plus rehabilitation treatment is feasible and safe, and that GH but not placebo slightly improves the SCI individual motor score. Moreover, we found that an intensive and long-lasting rehabilitation program per se increases the functional outcome of SCI individuals. To understand the possible mechanisms of the improvement due to GH treatment (motor score) and due to rehabilitation (functional outcome), we used a proteomic approach. Here, we used a multiple proteomic strategy to search for recovery biomarkers in blood plasma with the potential to predict response to somatropin treatment and to delayed intensive rehabilitation. Forty-six patients were recruited and followed for a minimum period of 1 year. Patients were classified into two groups based on their treatment: recombinant somatropin (0.4 mg) or placebo. Both groups received rehabilitation treatment. Our strategy allowed us to perform one of the deepest plasma proteomic analyses thus far, which revealed two proteomic signatures with predictive value: (i) response to recombinant somatropin treatment and (ii) response to rehabilitation. The proteins implicated in these signatures are related to homeostasis, inflammation, and coagulation functions. These findings open novel possibilities to assess and therapeutically manage patients with SCI, which could have a positive impact on their clinical response.

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