scholarly journals EVALUATION OF CASES OF EXOPHYTIC VERRUCOUS HYPERPLASIA IN ORAL SUBMUCOUS FIBROSIS IN BIHAR

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Richa Dubey
Keyword(s):  
Growth Pattern ◽  
Histopathological Examination ◽  
Essential Feature ◽  
Verrucous Carcinoma ◽  
Oral Submucous Fibrosis ◽  
Normal Epithelium ◽  
Medical College ◽  
Verrucous Hyperplasia ◽  
Submucous Fibrosis ◽  
Auto Fluorescence

Verrucous hyperplasia probably represents a morphological variant of verrucous carcinoma by Slootwage J P and Muller H (1983). An essential feature in distinguishing verrucous hyperplasia from verrucous carcinoma is the location of the thickened epithelium with respect to adjacent normal appearing epithelium. In verrucous hyperplasia most of the hyperplastic broadened rete ridges lay above the adjacent normal epithelium while verrucous carcinoma on contrary exhibits a downward growth pattern of otherwise similar rete ridges. Hence based on above findings the present study was planned in Evaluation of Cases of Exophytic Verrucous Hyperplasia in Oral Submucous Fibrosis in Bihar. The present study was planned in Department of Dentistry, netaji subhash Medical College & Hospital, Bihta, Patna, Bihar. Conventional oral examination (COE) of 30 patients with Oral submucous fibrosis (OSMF) was performed using incandescent operatory light. Out of that 6 cases having Verrucopapillary lesion were evaluated in the present study. The data generated from the present study concluded that patients with highly suspicious malignant verrucous growths on VEL scope examination exhibited increased auto fluorescence and on histopathological examination revealed no signs of dysplasia or invasion. Exhibition of increased autofluorescence of these lesions on VELscope examination could greatly help to determine their nondysplastic nature. Keywords: Verrucous hyperplasia, Verrucous carcinoma, Oral Submucous Fibrosis, etc.

scholarly journals CLINICAL ASSESSMENT OF OCCURRENCE OF ORAL SUBMUCOUS FIBROSIS IN PATIENTS FROM PATNA DENTAL COLLEGE & HOSPITAL

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Tanoj Kumar ◽  
Anurag Rai ◽  
Dr. Minti Kumari ◽  
Dr. Shweta Rai ◽  
Dr. Avanindra Kumar ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Clinical Assessment ◽  
Histopathological Examination ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Oral Pathology ◽  
Areca Nut ◽  
College Hospital ◽  
Medical College ◽  
Submucous Fibrosis

Oral submucous fibrosis is a chronic progressive scarring disease of oral cavity and oropharynx characterized by epithelial atrophy and juxta epithelial inflammatory reaction with progressive fibrosis of the lamina propria and deeper connective tissue. The resulting stiffness of the oral mucosa then causes a progressive decrease in mouth opening. Hence based on above findings the present study was planned for Clinical Assessment of Occurrence of Oral Submucous Fibrosis in Patients from Patna Medical College & Hospital. The present study was planned in Department of Oral Pathology, Patna Dental College & Hospital, Patna. Total 50 cases of the patient diagnosed with the Oral Sub mucous Fibrosis (OSMF) were evaluated in the present study. History, examination and investigation of patients were done in detail as per predesigned proforma. Histopathological examination of biopsy tissue from oral mucosa was done in patients who had taken pre-therapy and post-therapy (if and when required). X-ray of temporomandibular joint was requested (whenever needed). OSMF is a commonly occurring and widely spread premalignant condition increasingly affecting the youth. The occurrence of OSMF in gutkha chewers is far faster and more severe as compared in other forms of areca nut products chewers. The easy availability and promotions of these areca nut products especially gutkha and pan masala outside the schools colleges and social places has impacted younger population in India which has led to the increased occurrence of OSMF. Keywords: Oral Submucous Fibrosis, OSFM, gutkha, pan masala, etc.

scholarly journals Use of buccal fat pad flap for premalignant buccal mucosa defect reconstruction

2020 ◽  
Vol 7 (11) ◽  
pp. 3769
Author(s):  
Pankaj Kshirsagar ◽  
Prabhat B. Nichkaode ◽  
Saicharan Reddy ◽  
Manichandra Reddy C.
Keyword(s):  
Buccal Mucosa ◽  
Postoperative Morbidity ◽  
Oral Submucous Fibrosis ◽  
Premalignant Lesions ◽  
Fast Method ◽  
Fat Pad ◽  
Medical College ◽  
Operative Complications ◽  
Submucous Fibrosis ◽  
Buccal Pad Of Fat

Premalignant lesions over buccal mucosa are very common in India, some of these lesions require excision leaving behind defects and various techniques can be used in reconstruction of these defects. Small palatal defect, oroantral fistulas have been successfully closed by buccal pad of fat flap. Aim of this study was to evaluate reconstruction of defects after excision of premalignant lesion over buccal mucosa using buccal pad of fat. 20 patients were selected for this study who presented with different premalignant lesions like erythroplakia, proliferative verrucous leukoplakia, chronic hyperplastic candidiasis, Oral submucous fibrosis over buccal mucosa in Dr. DY Patil medical college surgery unit 4 and 7. Excision of lesion followed by reconstruction with buccal pad of fat was done. Patients were followed up every 14 days for 14 weeks, and was evaluated for epithelisation of flap and post-operative complications like infection and flap necrosis and also the functionality of the flap. In this study we have observed complete epithelisation of the flap in most of our patients. Dehiscence of the wound was observed in 3 of the patients with large defects (>4×5 cm). No postoperative morbidity was in postoperative patients. Buccal pad of fat is an excellent technique for reconstruction of small defects of buccal mucosa. It is a reliable and a fast method which has easy accessibility less complications and minimal morbidity.

scholarly journals Effectiveness of Pentoxifylline Therapy for Management of Oral Submucous Fibrosis

2022 ◽  
Vol 19 (1) ◽  
pp. 51-54
Author(s):  
Dwarika Prasad Bajgai ◽  
Bela Agrawal ◽  
Abadhesh Yadav
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Oral Disease ◽  
Medical College ◽  
Adjacent Structures ◽  
Group A ◽  
Submucous Fibrosis ◽  
Group B

Introduction: Oral submucous fibrosis is a chronic oral disease characterized by progressive buildup of constricting collagen bands in the cheeks and adjacent structures of the mouth due to chewing of areca nut. This can severely restrict mouth opening and tongue movement causing pain and burning sensation in the mouth. Aims: This study evaluates the efficacy of pentoxifylline in the management of oral submucous fibrosis. Methods: A hospital-based study, conducted in the dental outpatient department of Nepalgunj Medical College from October 2019 to September 2020. Forty-nine patients who were diagnosed histopathologically with oral submucous fibrosis were included. The patients were divided into two groups. In group A, patients were given, 200 mg thrice daily for first 30 days, then dose hiked to 400 mg thrice daily for two more months. Group B patients received treatment with multi-vitamin capsules (B-complex one capsule before sleep daily) for three months. All patients were followed up for six months and were assessed for maximum inter-incisor opening, pain on opening of mouth and burning sensation. Results: There was no statistical difference in mouth opening at baseline and first follow up. The mouth opening was significantly more in group A compared to group B from second follow up which persisted till third follow up (p <0.05). Pain and burning sensation significantly reduced in group A compared to group B from 2nd follow up which persisted till 3rd follow up (p <0.05). Few patients had nausea, dyspepsia and vomiting during treatment in group A which resolved within a few days without the need for cessation of the drug. Conclusion: Pentoxifylline can bring about significant clinical improvements in the symptoms of oral submucous fibrosis like mouth opening, pain and burning sensation, thereby improving the quality of life of the affected individuals.

scholarly journals Oral submucous fibrosis: is it a collagen disease? A study in search for its aetiology

2019 ◽  
Vol 5 (3) ◽  
pp. 690
Author(s):  
Mohan Bansal
Keyword(s):  
Oral Submucous Fibrosis ◽  
Tertiary Care ◽  
Geographical Area ◽  
Collagen Disease ◽  
College Hospital ◽  
Medical College ◽  
Uncommon Disease ◽  
Autoimmune Conditions ◽  
Submucous Fibrosis ◽  
Haematological Study

<p class="abstract"><strong>Background:</strong> The aetiopathogenesis of oral submucous fibrosis (OSMF), though not an uncommon disease, is not yet well established. OSMF is prevalent in the geographical area of study. These were the driving factors to conduct this study. This haematological study in patients with oral submucous fibrosis was conducted to find out some definite causative features so that an effective treatment regime could be evolved.</p><p class="abstract"><strong>Methods:</strong> This prospective hospital-based observational study was conducted in the Department of Otorhinolaryngology (ENT) and Pathology in a tertiary care medical college hospital. The 150 clinically diagnosed patients were enrolled for the study. Routine laboratory tests were done to identify markers which would suggest autoimmune conditions.  </p><p class="abstract"><strong>Results:</strong> In 124 cases (83%), mild to moderately anaemia was observed while 75 cases (50%) showed raised ESR. Lymphocytosis and eosinophilia were observed in 42 cases (28%) and 48 cases (32%) respectively. Hyperglobulinaemia was observed in 45 cases (30%). In 18 cases (12%) leukocytosis was observed. In 30 cases (20%), pus cells were seen in urine, while ova and cysts were found present in 42 cases (28%).</p><p class="abstract"><strong>Conclusions:</strong> The present study could not establish the commonly claimed theory of collagen disease. The exact aetiology of OSMF is not yet known. Some genetic factors seem to play a role, which make some people predisposed to react abnormally to chronic masticatories of different forms of areca nut, tobacco and areca leaves. Therefore further research in the direction of genetic studies will perhaps reveal the exact cause of OSMF.</p>

scholarly journals Verrucous carcinoma on pre-existing oral submucous fibrosis

2015 ◽  
Vol 27 (4) ◽  
pp. 593
Author(s):  
Sourav Malhotra ◽  
Vijay Raghavan ◽  
Abhishek Kumar ◽  
AbhishekKumar Singh
Keyword(s):  
Verrucous Carcinoma ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Verrucous carcinoma in association with oral submucous fibrosis

2011 ◽  
Vol 22 (4) ◽  
pp. 615 ◽  
Author(s):  
C Pravda ◽  
D Koteeswaran ◽  
H Srinivasan ◽  
LArathy Manohar
Keyword(s):  
Verrucous Carcinoma ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Application of injection Kenacort, intradermal route in oral submucous fibrosis

2020 ◽  
Vol 6 (2) ◽  
pp. 316
Author(s):  
Manjunath K. ◽  
Amardeep Singh ◽  
Manjunatha Rao S. V.
Keyword(s):  
Soft Tissues ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Cost Effective ◽  
Intradermal Injection ◽  
Research Centre ◽  
P Value ◽  
Medical College ◽  
History Of ◽  
Submucous Fibrosis

<p class="abstract"><strong>Background:</strong> Oral submucous fibrosis is a potentially pre-malignant disease, that results in progressive juxta-epithelial fibrosis of oral soft tissues, resulting in increased loss of tissue mobility, marked rigidity and inability to open the mouth. Actual treatment includes iron, multi vitamins, lycopene, pentoxifyline, steroid injections and human placental extracts. Currently available treatment with intradermal injection of Kenacort with hyaluronidase is effective to some extent.</p><p class="abstract"><strong>Methods:</strong> This study was conducted at Basaveshwara Medical College and Hospital, Research Centre, Chitradurga, Karnataka, in the Otorhinolaryngology Department from February 2019 to August 2019 for 6 months duration. A total of 40 patients were included in this study. Mouth opening was recorded from baseline to 6 weeks. Cases were followed up for 6 months thereafter. Patients with positive history of chewing of betel-nuts, pan, gutkha and age from 18-50 years males and females were included in this study. Patients undergoing any surgery, allergic conditions, age more than 50 years were excluded. Mouth opening was assessed by objective type and subjective type.</p><p class="abstract"><strong>Results:</strong> There was significant increase in mouth opening in patients after administration of intra-dermal Kenacort injection and oral lycopene. The results were statistically significant and patients responded better and p value &lt;0.001.</p><p class="abstract"><strong>Conclusions:</strong> Management of moderate oral submucous fibrosis should include counselling of patients along with oral lycopene with intradermal injection of Kenacort with hyaluronidase, is highly efficacious and cost- effective in improving the mouth opening and reducing other symptoms in patients with OSMF, whereas advanced stages should be treated surgically.</p>

Oral Verrucous Hyperplasia: A Case Report

2019 ◽  
Vol 11 (1) ◽  
pp. 56-61
Author(s):  
Dr. Sanjeela Guru ◽  
Dr. Adithya Reddy ◽  
Dr. Shyam Padmanabhan ◽  
Dr. Rakshith Guru
Keyword(s):  
Case Report ◽  
Present Article ◽  
Histopathological Examination ◽  
Verrucous Carcinoma ◽  
Alveolar Ridge ◽  
Histopathologic Examination ◽  
Oral Mucous Membrane ◽  
Verrucous Hyperplasia ◽  
The Right

Oral Verrucous Hyperplasia is considered as an initialtype of verrucous carcinoma, representing a plausible malignant transformationof the oral mucous membrane. Studies have documented that verrucous hyperplasia transforms into verrucous carcinoma quite consistently and hence both theselesions should be managed identically. The present article reports the case of a 62-year-old male patient whoseprimary complaintwas that of a non-scrapableexophytic warty white outgrowth on edentulous alveolar ridge in the right upper posterior tooth region of the jaw. The growth was provisionally diagnosed as Squamous papilloma. Excision of the exophyticlesion was doneand the tissue biopsy sent for histopathological examination. Histopathologic examination suggested that the lesion was Oral Verrucous hyperplasia. 3 month follow-up of the patient revealed no signs of recurrence.

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