scholarly journals Sodium bicarbonate ingestion does not restore the decrement in high-intensity exercise capacity induced by a 27 h Fast

2014 ◽  
pp. 18-24
Author(s):  
C. P. Lambert ◽  
D. Ball ◽  
R. J. Maughan
Keyword(s):  
Sodium Bicarbonate ◽  
Exercise Capacity ◽  
High Intensity ◽  
High Intensity Exercise

Протягом 24 годин швидко скорочується час виснаження, практично на 100 % відновлюється показник VO 2 max по відношенню до 4 годин постпоглинаючого стану. Наслідком такого стану може бути метаболічний ацидоз, який є причиною передчасної втоми. Мета цього дослідження – регуляція рівня бікарбонату натрію завдяки пероральному прийому протягом одного дня (24 години) з метою прискорення та визначення толерантності відновлення організму після фізичного навантаження у поствідновлювальному періоді (3 години після завершення). У дослідженнях брали участь шість здорових чоловіків за особистою письмовою згодою. У ході дослідження проводилось вивчення підвищення відновлення організму після тривалого фізичного навантаження на фоні прийому спеціальних бикарбонат натрію складових фармакологічних препаратів по відношенню до результатів осіб, які приймали препарати типу «плацебо» і знаходились у звичайному для них (щоденному) режимі харчування.

Six weeks of a polarized training-intensity distribution leads to greater physiological and performance adaptations than a threshold model in trained cyclists

2013 ◽  
Vol 114 (4) ◽  
pp. 461-471 ◽  
Author(s):  
Craig M. Neal ◽  
Angus M. Hunter ◽  
Lorraine Brennan ◽  
Aifric O'Sullivan ◽  
D. Lee Hamilton ◽  
...  
Keyword(s):  
Exercise Capacity ◽  
Intensity Distribution ◽  
High Intensity ◽  
Threshold Model ◽  
Endurance Performance ◽  
High Intensity Exercise ◽  
Metabolic Adaptation ◽  
Mitochondrial Enzyme ◽  
Training Intensity ◽  
Metabolomics Analysis

This study was undertaken to investigate physiological adaptation with two endurance-training periods differing in intensity distribution. In a randomized crossover fashion, separated by 4 wk of detraining, 12 male cyclists completed two 6-wk training periods: 1) a polarized model [6.4 (±1.4 SD) h/wk; 80%, 0%, and 20% of training time in low-, moderate-, and high-intensity zones, respectively]; and 2) a threshold model [7.5 (±2.0 SD) h/wk; 57%, 43%, and 0% training-intensity distribution]. Before and after each training period, following 2 days of diet and exercise control, fasted skeletal muscle biopsies were obtained for mitochondrial enzyme activity and monocarboxylate transporter (MCT) 1 and 4 expression, and morning first-void urine samples were collected for NMR spectroscopy-based metabolomics analysis. Endurance performance (40-km time trial), incremental exercise, peak power output (PPO), and high-intensity exercise capacity (95% maximal work rate to exhaustion) were also assessed. Endurance performance, PPOs, lactate threshold (LT), MCT4, and high-intensity exercise capacity all increased over both training periods. Improvements were greater following polarized rather than threshold for PPO [mean (±SE) change of 8 (±2)% vs. 3 (±1)%, P < 0.05], LT [9 (±3)% vs. 2 (±4)%, P < 0.05], and high-intensity exercise capacity [85 (±14)% vs. 37 (±14)%, P < 0.05]. No changes in mitochondrial enzyme activities or MCT1 were observed following training. A significant multilevel, partial least squares-discriminant analysis model was obtained for the threshold model but not the polarized model in the metabolomics analysis. A polarized training distribution results in greater systemic adaptation over 6 wk in already well-trained cyclists. Markers of muscle metabolic adaptation are largely unchanged, but metabolomics markers suggest different cellular metabolic stress that requires further investigation.

EFFECT OF ORALLY ADMINISTERED SODIUM BICARBONATE ON PERFORMANCE OF HIGH INTENSITY EXERCISE

1985 ◽  
Vol 17 (2) ◽  
pp. 200-201 ◽  
Author(s):  
R. R. Pate ◽  
P. E. Smith ◽  
M. I. Lambert ◽  
M. L. Rocchio
Keyword(s):  
Sodium Bicarbonate ◽  
High Intensity ◽  
High Intensity Exercise

Effects of Oral D-Ribose Supplementation on Anaerobic Capacity and Selected Metabolic Markers in Healthy Males

2003 ◽  
Vol 13 (1) ◽  
pp. 76-86 ◽  
Author(s):  
R.B. Kreider ◽  
C. Melton ◽  
M. Greenwood ◽  
C. Rasmussen ◽  
J. Lundberg ◽  
...  
Keyword(s):  
Exercise Capacity ◽  
High Intensity ◽  
Repeated Measures ◽  
Adenine Nucleotide ◽  
Average Power ◽  
Anaerobic Capacity ◽  
Cycle Ergometer ◽  
High Intensity Exercise ◽  
Anaerobic Exercise ◽  
Metabolic Markers

Oral D-ribose supplementation has been reported to increase adenine nucle-otide synthesis and exercise capacity in certain clinical populations. Theoretically, increasing adenine nucleotide availability may enhance high intensity exercise capacity. This study evaluated the potential ergogenic value of D-ribose supplementation on repetitive high-intensity exercise capacity in 19 trained males. Subjects were familiarized to the testing protocol and performed two practice-testing trials before pre-supplementation testing. Each test involved warming up for 5 min on a cycle ergometer and then performing two 30-s Wingate anaerobic sprint tests on a computerized cycle ergometer separated by 3 min of rest recovery. In the pre- and post-supplementation trials, blood samples were obtained at rest, immediately following the first and second sprints, and following 5 min of recovery from exercise. Subjects were then matched according to body mass and anaerobic capacity and assigned to ingest, in a randomized and double blind manner, capsules containing either 5 g of a dextrose placebo (P) or D-ribose (R) twice daily (10 g/d) for 5 d. Subjects then performed post-supplementation tests on the 6th day. Data were analyzed by ANOVA for repeated measures. Results revealed a significant interaction (p = .04) in total work output. Post hoc analysis revealed that work significantly declined (–18 ± 51 J) during the second post-supplementation sprint in the P group while being maintained in the R group (–0.0 ± 31 J). No significant interactions were observed in peak power, average power, torque, fatigue index, lactate, ammonia, glucose, or uric acid. Results indicate that oral ribose supplementation (10 g/d for 5 d) does not affect anaerobic exercise capacity or metabolic markers in trained subjects as evaluated in this study.

The Effect of Sodium Bicarbonate Supplementation on the Decline in Gross Efficiency During a 2000-m Cycling Time Trial

2020 ◽  
Vol 15 (5) ◽  
pp. 741-747 ◽  
Author(s):  
Anna E. Voskamp ◽  
Senna van den Bos ◽  
Carl Foster ◽  
Jos J. de Koning ◽  
Dionne A. Noordhof
Keyword(s):  
Sodium Bicarbonate ◽  
High Intensity ◽  
Lactate Concentration ◽  
Time Trial ◽  
High Intensity Exercise ◽  
Concentration Data ◽  
Double Blind ◽  
Cycling Time Trial ◽  
Gross Efficiency ◽  
Cycling Time

Background: Gross efficiency (GE) declines during high-intensity exercise. Increasing extracellular buffer capacity might diminish the decline in GE and thereby improve performance. Purpose: To examine if sodium bicarbonate (NaHCO3) supplementation diminishes the decline in GE during a 2000-m cycling time trial. Methods: Sixteen male cyclists and 16 female cyclists completed 4 testing sessions including a maximal incremental test, a familiarization trial, and two 2000-m GE tests. The 2000-m GE tests were performed after ingestion of either NaHCO3 supplements (0.3 g/kg body mass) or placebo supplements (amylum solani, magnesium stearate, and sunflower oil capsules). The GE tests were conducted using a double-blind, randomized, crossover design. Power output, gas exchange, and time to complete the 2000-m time trials were recorded. Capillary blood samples were analyzed for blood bicarbonate, pH, and lactate concentration. Data were analyzed using magnitude-based inference. Results: The decrement in GE found after the 2000-m time trial was possibly smaller in the male and female groups after NaHCO3 than with placebo ingestion, with the effect in both groups combined being unclear. The effect on performance was likely trivial for males (placebo 164.2 [5.0] s, NaHCO3 164.3 [5.0] s; Δ0.1; ±0.6%), unclear for females (placebo 178.6 [4.8] s, NaHCO3 178.0 [4.3] s; Δ−0.3; ±0.5%), and very likely trivial when effects were combined. Blood bicarbonate, pH, and lactate concentration were substantially elevated from rest to pretest after NaHCO3 ingestion. Conclusions: NaHCO3 supplementation results in an unclear effect on the decrease in GE during high-intensity exercise and in a very likely trivial effect on performance.

scholarly journals Greater lactate accumulation following an acute bout of high-intensity exercise in males suppresses acylated ghrelin and appetite postexercise

2020 ◽  
Vol 128 (5) ◽  
pp. 1321-1328 ◽  
Author(s):  
Luke W. Vanderheyden ◽  
Greg L. McKie ◽  
Greg J. Howe ◽  
Tom J. Hazell
Keyword(s):  
Sodium Bicarbonate ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Acylated Ghrelin ◽  
Acute Bout ◽  
Lactate Accumulation ◽  
Appetite Suppression ◽  
Exercise Induced ◽  
Dependent Mechanism ◽  
Caloric Deficit

We used sodium bicarbonate to increase lactate accumulation or sodium chloride as a placebo. Our findings further implicate lactate as a mediator of exercise-induced appetite suppression given exercise-induced increases in lactate during the sodium bicarbonate session altered peripheral concentrations of appetite-regulating hormones, culminating in a reduction of appetite. This supports a lactate-dependent mechanism of appetite suppression following high-intensity exercise and highlights the potential of using lactate as a means of inducing a caloric deficit.

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