Preparation and Characterization of New Heterocyclic Derivatives, Six and Five Ring from Acetanilide

2020 ◽  
pp. 87-89
Keyword(s):  
Physical Properties ◽  
Sodium Hydroxide ◽  
Hydrazine Hydrate ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Room Temperature ◽  
13C Nmr Spectra ◽  
Dilute Solution ◽  
Heterocyclic Derivatives

The aim of the study synthesis of new heterocyclic derivatives (six and five ring) from acetanilide. Firstly the chalcones have been synthesized from the reaction acetanilide with aromatic aldehyde [ 2-nitrobenzaldyhade, 4- dimethylaminobenzaldehyde, 2-naphthaldehyde ] in dilute solution of ethanolic sodium hydroxide at room temperature. This reaction occurs depending on Claisen Schmidt condensation, then a new oxazine and thiazine derivatives (six ring) have been synthesized by the reaction chalcones with urea and thiourea. Finally the synthesized chalcones were reacted with hydrazine hydrate to produce new pyrazol derivatives (five ring). All derivatives were characterized by physical properties, FTIR, 1H-NMR and 13C-NMR spectra.

Synthesis and Characterization of N-butyl-N-methylimidazolium- D-(-)-tartrate Chiral Ionic Liquid

2012 ◽  
Vol 518-523 ◽  
pp. 3989-3992 ◽  
Author(s):  
Yang Zhang ◽  
Xiao Hua Tu ◽  
Cheng Ping Miao ◽  
Jian Yi Wu
Keyword(s):  
Ionic Liquid ◽  
1H Nmr ◽  
Ion Chromatography ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Optical Rotation ◽  
Synthesis And Characterization ◽  
13C Nmr Spectra ◽  
Chiral Ionic Liquid

A novel CIL of N-butyl-N-methyl imidazolium-D-(-)-tartrate has been designed and synthesized by neutralization reaction. Its structure was characterized by 1H-NMR and 13C-NMR spectra, the optical rotation was characterized by polarimeter with the value of-15.0º, and the purity was characterized by ion chromatography with the value of 98.4%.

scholarly journals Synthesis and characterization of new Oxazine , Thiazine and Pyrazol derived from chalcones

2014 ◽  
Vol 11 (2) ◽  
pp. 477-485 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Nmr Spectroscopy ◽  
Hydrazine Hydrate ◽  
Elemental Analysis ◽  
Potassium Hydroxide ◽  
1H Nmr Spectroscopy ◽  
Room Temperature ◽  
Potassium Hydroxide Solution ◽  
Synthesis And Characterization ◽  
Heterocyclic Derivatives

In this study, chalcones were synthesis by condensing 2-acetylpyridine with aromatic aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation. After that, new heterocyclic derivatives such as Oxazine, Thiazine and Pyrazol were synthesis by reaction between chalcones with urea, thiourea and hydrazine hydrate respectively scheme 1. All these compounds wrer characterization by FTIR, 1H-NMR spectroscopy and elemental analysis.

scholarly journals Direct Access to (±)-10-Desbromoarborescidine A from Tryptamine and Pentan-1,5-diol

2019 ◽  
Author(s):  
Apurba Ranjan Sahoo ◽  
Gummidi Lalitha ◽  
V. Murugesh ◽  
Christian Bruneau ◽  
Gangavaram V. M. Sharma ◽  
...  
Keyword(s):  
13C Nmr ◽  
Nmr Spectra ◽  
Ruthenium Complex ◽  
Single Step ◽  
Direct Access ◽  
Condensation Process ◽  
13C Nmr Spectra ◽  
Synthetic Strategy ◽  
Supporting Material

A single step synthetic strategy for (±)10- Desbromoarborescidine A is described. Starting from tryptamine and pentan-1,5-diol, this acceptorless dehydrogenative condensation process is efficiently catalyzed by a ruthenium complex featuring proton-responsive phosphine pyridone ligand.<div>Manuscript is available supporting material is available and includes experimental procedures, characterization of compounds, 1H, 13C NMR spectra and chromatograms.</div>

scholarly journals Synthesis of Novel N-Acylhydrazones and Their C-N/N-N Bond Conformational Characterization by NMR Spectroscopy

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4908
Author(s):  
Rubina Munir ◽  
Noman Javid ◽  
Muhammad Zia-ur-Rehman ◽  
Muhammad Zaheer ◽  
Rahila Huma ◽  
...  
Keyword(s):  
13C Nmr ◽  
Nmr Spectra ◽  
Room Temperature ◽  
Aromatic Aldehydes ◽  
Spectral Studies ◽  
13C Nmr Spectra ◽  
1H And 13C Nmr ◽  
Mass Spectral ◽  
Nmr Techniques ◽  
Ft Ir

In this article, a synthesis of N’-(benzylidene)-2-(6-methyl-1H-pyrazolo[3,4-b]quinolin-1-yl)acetohydrazides and their structural interpretation by NMR experiments is described in an attempt to explain the duplication of some peaks in their 1H- and 13C-NMR spectra. Twenty new 6-methyl-1H-pyrazolo[3,4-b]quinoline substituted N-acylhydrazones 6(a–t) were synthesized from 2-chloro-6-methylquinoline-3-carbaldehyde (1) in four steps. 2-Chloro-6-methylquinoline-3-carbaldehyde (1) afforded 6-methyl-1H-pyrazolo[3,4-b]quinoline (2), which upon N-alkylation yielded 2-(6-methyl-1H-pyrazolo[3,4-b]quinolin-1-yl)acetate (3). The hydrazinolysis of 3 followed by the condensation of resulting 2-(6-methyl-1H-pyrazolo[3,4-b]quinolin-1-yl)acetohydrazide (4) with aromatic aldehydes gave N-acylhydrazones 6(a–t). Structures of the synthesized compounds were established by readily available techniques such as FT-IR, NMR and mass spectral studies. The stereochemical behavior of 6(a–t) was studied in dimethyl sulfoxide-d6 solvent by means of 1H NMR and 13C NMR techniques at room temperature. NMR spectra revealed the presence of N’-(benzylidene)-2-(6-methyl-1H-pyrazolo[3,4-b]quinolin-1-yl)acetohydrazides as a mixture of two conformers, i.e., E(C=N)(N-N) synperiplanar and E(C=N)(N-N)antiperiplanar at room temperature in DMSO-d6. The ratio of both conformers was also calculated and E(C=N) (N-N) syn-periplanar conformer was established to be in higher percentage in equilibrium with the E(C=N) (N-N)anti-periplanar form.

scholarly journals Direct Access to (±)-10-Desbromoarborescidine A from Tryptamine and Pentan-1,5-diol

2019 ◽  
Author(s):  
Apurba Ranjan Sahoo ◽  
Gummidi Lalitha ◽  
V. Murugesh ◽  
Christian Bruneau ◽  
Gangavaram V. M. Sharma ◽  
...  
Keyword(s):  
13C Nmr ◽  
Nmr Spectra ◽  
Ruthenium Complex ◽  
Single Step ◽  
Direct Access ◽  
Condensation Process ◽  
13C Nmr Spectra ◽  
Synthetic Strategy ◽  
Supporting Material

A single step synthetic strategy for (±)10- Desbromoarborescidine A is described. Starting from tryptamine and pentan-1,5-diol, this acceptorless dehydrogenative condensation process is efficiently catalyzed by a ruthenium complex featuring proton-responsive phosphine pyridone ligand.<div>Manuscript is available supporting material is available and includes experimental procedures, characterization of compounds, 1H, 13C NMR spectra and chromatograms.</div>

Determination of the Structure of Chlorobutyl and Bromobutyl Rubber by NMR Spectroscopy

1987 ◽  
Vol 60 (4) ◽  
pp. 636-646 ◽  
Author(s):  
Chia Yeh Chu ◽  
Kenneth Norman Watson ◽  
Rastko Vukov
Keyword(s):  
Nmr Spectroscopy ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Broad Band ◽  
Type Structure ◽  
13C Nmr Spectra ◽  
Model Compounds ◽  
1H And 13C Nmr

Abstract An analysis of the 1H and 13C NMR spectra of the chlorobutyl and bromobutyl rubbers was performed. Peaks were assigned based on evidence from broad-band decoupled, off-resonance decoupled, selectively decoupled and J-modulated spectra, the known characterization of butyl rubber and halogenation studies on model compounds. The assignment of the minor peaks indicated that the exomethylene-type structure is predominant in both halogenated rubbers. They also contain some nonhalogenated isoprenyl units. Bromobutyl rubber also contains some α-bromomethyl-type structures resulting from rearrangement of the exomethylene structure. The presence of endo-type structures will require further study for confirmation.

scholarly journals Synthesis and Characterization of New 2-Quinolone Sulfonamide Derivatives

2016 ◽  
Vol 13 (4) ◽  
pp. 806-818
Author(s):  
Baghdad Science Journal
Keyword(s):  
Nitric Acid ◽  
13C Nmr ◽  
Ethyl Acetoacetate ◽  
Nmr Spectra ◽  
Synthesis And Characterization ◽  
13C Nmr Spectra ◽  
Substituted Phenols ◽  
Ft Ir ◽  
Quinolone Derivatives

A series of new 2-quinolone derivatives linked to benzene sulphonyl moieties were performed by many steps: the first step involved preparation of different coumarins (A1,A2) by condensation of different substituted phenols with ethyl acetoacetate. The compound A1 was treated with nitric acid to afford two isomers of nitrocoumarin derivatives (A3) and (A4). The prepared compounds (A2, A3) were treated with hydrazine hydrate to synthesize different 2-quinolone compounds (A5,A6) while the coumarin treated with different amines gave compounds (A7,A8). Then the synthesized 2-quinolone compounds (A5-A8) treated with benzene sulphonyl chloride to afford new sulfonamide derivatives (A9-A12). The synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra and by measurement some of their physical properties.

scholarly journals A New Derivatives of Benzodiazepine, Imidazole, Isatin, Maleimide, Pyrimidine and 1,2,4-Triazole: Synthesis and Characterization

2008 ◽  
Vol 5 (2) ◽  
pp. 305-312
Author(s):  
Baghdad Science Journal
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Synthesis And Characterization ◽  
13C Nmr Spectra ◽  
Organic Reagents ◽  
Cyclocondensation Reaction ◽  
Heterocyclic Derivatives ◽  
Ft Ir ◽  
Derivatives Of

The synthesis of new benzodiazepine, imidazole, isatin, maleimide, pyrimidine and 1,2,4-triazole derived from 2-amino-4-hydroxy-1,3,5-triazine, via its cyclocondensation reaction with different organic reagents, is described. FT-IR, 1H-NMR and as well as 13C-NMR spectra disclosed the structures of the precursors and heterocyclic derivatives formed.

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