scholarly journals A new automated method for the determination of erythrocyte sedimentation rate (ESR)

2007 ◽  
Vol 2 (3) ◽  
pp. 64-69
Author(s):  
Ahmed A. Ibrahim
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Automated Method ◽  
Erythrocyte Sedimentation

C-REACTIVE PROTEIN IN THE SERUM IN NEPHROSIS AND ACUTE GLOMERULONEPHRITIS

PEDIATRICS ◽  
1960 ◽  
Vol 25 (1) ◽  
pp. 106-111
Author(s):  
Aree Valyasevi ◽  
Joseph M. Sloan ◽  
Lewis A. Barness
Keyword(s):  
Nephrotic Syndrome ◽  
Hormone Therapy ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Positive Test ◽  
Acute Glomerulonephritis ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

C-reactive protein in the serum and the erythrocyte sedimentation rate were followed serially in 13 patients with acute nephritis and in 9 patients with the nephrotic syndrome. Although a positive C-reactive protein test was always associated with evidence of infection, obvious infection in a few instances was not accompanied by a positive test. Determination of C-reactive protein is valuable in determining the presence of infection in patients with acute nephritis and the nephrotic syndrome, especially in the latter where hormone therapy may mask many signs of infection.

scholarly journals Comparative Analysis of Erythrocyte Sedimentation Rate Measured by Automated and Manual Methods in Anaemic Patients

2020 ◽  
Vol 12 (04) ◽  
pp. 239-243
Author(s):  
Vikram Narang ◽  
Sumit Grover ◽  
Amandeep Kaur Kang ◽  
Avantika Garg ◽  
Neena Sood
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Manual Measurement ◽  
Automated Method ◽  
Erythrocyte Sedimentation ◽  
Manual Methods ◽  
Automated Instrument ◽  
Very High ◽  
Edta Blood ◽  
High Range

Abstract Purpose Erythrocyte sedimentation rate (ESR) is a widely used indicator of inflammation and a routinely done hematology investigation to monitor patients of autoimmune and infectious diseases. We aimed to compare the ESR results obtained by Roller 20LC automated instrument and standard reference Westergren method and analyzed the effect of anemia (hematocrit) on ESR measurements through the automated method. Methods We analyzed 1377 random anemic OPD patients (hematocrit [HCT] < 35%) for ESR levels measured by Roller 20LC using EDTA blood and Westergren method using citrated blood for a one and half year period from January 1, 2018 to June 30, 2019. Fabry’s formula was used to correct the Westergren ESR. Results The total number of samples after evaluation were divided into low (n = 232), intermediate (n = 417), high (n = 406), and very high range of ESR (≥100 mm/hr; n = 422). Mean difference between values of corrected and automated ESR for the low, intermediate, high and very high ESR range was 2.33 ± 5.03, 10.95 ± 8.04, 28.22 ± 19.11 and 43.3 ± 19.22 mm/hr, respectively. The 95% limit of agreement calculated by the Bland–Altmann analysis between the two methods for low-ESR range was −7.53 to 12.2 (highest correlation coefficient –0.65), while for very high ESR, range was −5.1 to 81.5 (least coefficient of 0.18) (p < 0.001). Conclusion In laboratories with high-sample load and where manual measurement may be tedious, the automated method of ESR measurement can safely replace the Westergren method for low-ESR values in patients with low hematocrit. While for high-ESR values, validation by the standard Westergren method may be needed.

scholarly journals Evaluation of micro-ESR method with Westergren method for determination of erythrocyte sedimentation rate

2018 ◽  
Vol 6 (2) ◽  
pp. 628 ◽  
Author(s):  
Kamal Preet ◽  
Vyankatesh T. Anchinmane ◽  
Shilpa Sankhe
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Regression Line ◽  
Reference Method ◽  
Old Patients ◽  
Testing Method ◽  
Erythrocyte Sedimentation ◽  
Method R ◽  
Very Old Patients

Background: Erythrocyte sedimentation rate (ESR) test provides valuable information in screening, diagnosis, as well as monitoring disease activity and therapeutic response in numerous health conditions. The most commonly used method for determination of ESR is Westergren method, which is time-consuming and requires a large amount of blood sample. There are several other methods, like Micro-ESR method which overcome the limitations of conventional Westergren method, hence the present study was performed to compare results of Westergren method with Micro-ESR method for determination of ESR.Methods: In the present study, blood samples from 100 patients were processed for ESR determination by Westergren method and Micro-ESR method. The results obtained were compared using Pearson’s correlation test.Results: The Westergren method was the reference method and the Micro-ESR method was testing method. The comparison was done between Micro- ESR method results (X-axis) and results of Westergren method (Y-axis). The slope of the regression line using linear regression was 1.010 with a y-intercept of -0.788. Statistical analysis demonstrated significant correlation of results of Micro-ESR method with Westergren method (r = 0.9977).Conclusions: Micro-ESR is a reliable and precise method for ESR measurement. The Micro- ESR method is simple to perform and requires very small volume of blood (0.2ml) as compared to conventional Westergren method. It can be potential useful tool in performing ESR determination especially for the patients with limitation of blood availability as pediatric patients and very old patients. 

scholarly journals Rapid determination of erythrocyte sedimentation rate (ESR) by an electrically driven blood droplet biosensor

2020 ◽  
Vol 14 (6) ◽  
pp. 064108
Author(s):  
Sumit Kumar ◽  
Rishi Ram ◽  
Arnab Sarkar ◽  
Sunando DasGupta ◽  
Suman Chakraborty
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Rapid Determination ◽  
Erythrocyte Sedimentation

scholarly journals Comparison of two different methods for the determination of erythrocyte sedimentation rate

2014 ◽  
Vol 5 (3) ◽  
Author(s):  
Şeyda Özdemir ◽  
Gülfer Öztürk ◽  
Aynur Altuntaş ◽  
Sümeyya Akyol ◽  
Erdem Bulut ◽  
...  
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Erythrocyte Sedimentation

Ves-Matic CUBE 200: is modified Westergren method for erythrocyte sedimentation rate a valid alternative to the gold standard?

2019 ◽  
Vol 72 (10) ◽  
pp. 716-719
Author(s):  
Ivana Lapić ◽  
Elisa Piva ◽  
Federica Spolaore ◽  
Giulia Musso ◽  
Francesca Tosato ◽  
...  
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Gold Standard ◽  
Method Comparison ◽  
Erythrocyte Sedimentation ◽  
Small Constant ◽  
Coefficients Of Variation ◽  
Key Points ◽  
Automated Determination

Ves-Matic CUBE 200 is an automated erythrocyte sedimentation rate (ESR) analyser based on the modified Westergren principle of measurement. In this study, we aimed to assess its analytical performance following the key points addressed by the International Council for Standardization in Haematology and the comparability with the gold standard Westergren method. Comparison of the two methods yielded a correlation coefficient of 0.852, no significant bias and a small constant difference between compared results. Intrarun coefficients of variation (CV) ranged from 2.2% to 22.2%, the higher being for lower ESR values, while inter-run CVs were 19.7% for the normal range and 3.0% for the abnormal range. This study proved the analytical validity of the Ves-Matic CUBE 200 and its high comparability with the Westergren method, showing obvious improvements in the technology applied for automated determination of ESR and a valuable step forward in standardisation of ESR methods.

Sign in / Sign up

Export Citation Format

Share Document