Case series study: the diagnosis and treatment of fifty tumors and pseudotumors at the proximal femur

MedPharmRes ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 40-46
Author(s):  
Ly Duc Minh Van ◽  
Thi Cao
Keyword(s):  
Giant Cell ◽  
Proximal Femur ◽  
Case Series ◽  
Clinical Findings ◽  
Functional Score ◽  
Giant Cell Tumors ◽  
Specific Tumor ◽  
Pathologic Fractures ◽  
Case Series Study ◽  
Fixation Devices

Introduction: Tumor and pseudotumor (TP) at the proximal femur (PF) can seriously affect mortality, extremity function, and body integrity. However, reports often focused on a specific tumor, not regional lesions. This study focuses on clinical findings, imaging, micro-pathology, and the treatment of all TP at the site. Methods: The study involved all patients who had a confirmed tumor or pseudotumor diagnosis at the PF. The clinical findings, X-ray, and biopsy were recorded and analyzed. Treatment was optional depending on the patient's situation and available condition of the hospital. The functional outcome, bone healing were defined at the last examination or two years of follow-up. Results: Fifty patients were involved in the study. Twenty-four patients had apparent tumors. TP at the PF, neck-trochanter, trochanters, and neck were 21 (42%), 16 (32%), 9 (18%), and 4 (8%) cases, respectively. There were 29 (58%) pathologic fractures. Biopsy was made for all patients. Twenty-three cases (46%) were malignant, and 8 (16%) cases were giant cell tumors. Thirtythree patients suffered from an operation. Ennerking's functional score was excellent, good, fair, and poor in 24 (48%), 5 (10%), 1 (2%), and 20 (40%) patients, respectively. For the last outcomes of 33 operated patients, 17 healed, three unchanged, one worse, and two dead. Conclusions: For the PF TP, the rate of malignant and pathological fracture was high. The giant cell tumor was not rare. The resection of the TP combined with grafts using ordinary fixation devices was satisfactory.

Imaging and Clinical Findings of Temporal Bone Giant Cell Tumors

Skull Base ◽  
2008 ◽  
Vol 18 (S 01) ◽  
Author(s):  
Masoud Zarandy ◽  
Mohammad Ashtiani ◽  
Nasrin Yazdani
Keyword(s):  
Giant Cell ◽  
Temporal Bone ◽  
Clinical Findings ◽  
Giant Cell Tumors

Do we need internal fixation devices for giant cell tumors around knee joint? An outcome study

2018 ◽  
Vol 1 (1) ◽  
pp. 33
Author(s):  
Ritesh Runu ◽  
Vidya Sagar ◽  
Ashutosh Kumar ◽  
Arnab Sinha ◽  
Santosh Kumar
Keyword(s):  
Knee Joint ◽  
Internal Fixation ◽  
Giant Cell ◽  
Outcome Study ◽  
Giant Cell Tumors ◽  
Fixation Devices

scholarly journals HAEMATOETIOLOGICAL EVALUATION OF SPLENOMEGALY

2020 ◽  
pp. 38-40
Author(s):  
Y.V.S. Prabhakar ◽  
Vasireddy Teja ◽  
Ponnaganti Vasundhara
Keyword(s):  
Case Series ◽  
Sampling Technique ◽  
Abdominal Ultrasound ◽  
Liver Function Tests ◽  
Clinical Findings ◽  
Haematological Parameters ◽  
Blood Picture ◽  
Additional Tool ◽  
Case Series Study ◽  
Series Study

BACKGROUND: Splenomegaly is usually the result of an underlying disorder.Causes ranging from infections to haematological malignancies. AIMS AND OBJECTIVES : Present study aims to find out the frequency of various haematological causes of splenomegaly and to study its haematological parameters . MATERIAL AND METHODS: This descriptive case series study was carried out at Department of Medicine at Nri General Hospital from 1st March 2019 to 31st August 2019,over a period of six months. 100 patients older than 13 years of age with clinically enlarged spleen were selected for this study. Sampling technique is Non propability convinient sampling. After getting informed consent from the patients proforma filled elaborating history, important clinical findings and investigations like abdominal ultrasound , complete blood picture , liver function tests , virals were performed. RESULTS: Males (57%) are most commonly affected than females (43%). The most common age group in males was 41-50 yrs and females was 21-30 yrs. The maximum cases were identified with moderate splenomegaly.Among the haematological causes 57% were leukemias,of which 30% were chronic and 27% were acute . CONCLUSION : Splenomegaly in a symptomatic person should always be investigated thoroughly as most of the cases are treatable. Haematological parameters with enlarged spleen is utmost important as an additional tool in evaluating the etiopathogenesis of splenomegaly.

scholarly journals Localized Tenosynovial Giant Cell Tumor: An Incidentally Found Lesion in the Shoulder

2021 ◽  
Vol 4 (2) ◽  
pp. 224-228
Author(s):  
Jorge Gomes Lopes ◽  
Manuel Gutierres ◽  
Luisa Vital ◽  
Miguel Relvas-Silva ◽  
Ricardo São-Simão ◽  
...  
Keyword(s):  
Giant Cell ◽  
Soft Tissues ◽  
Standard Treatment ◽  
Treatment Strategies ◽  
Case Series ◽  
Giant Cell Tumors ◽  
Tenosynovial Giant Cell Tumor ◽  
Complete Surgical Resection ◽  
Low Incidence ◽  
Specific Symptoms

The concept of localized and diffuse tenosynovial giant cell tumors (TSGCT) is recent and may still cause some confusion among surgeons. This disorder constitutes a family of proliferative lesions characterized by their origin in the articular synovium, tendon sheaths, or bursa. It is not always easy to diagnose this pathology, especially due to its multitude of presentation. We describe an incidentally found localized TSGCT intra-articularly located in the shoulder. The localized lesions are considered a more benign form that usually present not with specific symptoms but rather a manifestation of the disturbance in the affected joint or the surrounding soft tissues. MRI is indispensable for its diagnosis, and the standard treatment is complete surgical resection. Due to its low incidence, it is difficult to find literature that goes beyond clinical reports or small case series. With this report, we intend to call readers’ attention for the variable presentations, the different diagnostic and treatment strategies, and the expected outcomes.

Surgical strategy for the management of sacral giant cell tumors: a 32-case series

2012 ◽  
Vol 12 (6) ◽  
pp. 484-491 ◽  
Author(s):  
Guodong Li ◽  
Dong Fu ◽  
Kai Chen ◽  
Xiaojun Ma ◽  
Mengxiong Sun ◽  
...  
Keyword(s):  
Giant Cell ◽  
Case Series ◽  
Surgical Strategy ◽  
Giant Cell Tumors

Giant Cell Tumors of the Skull Base: Case Series and Current Concepts

2013 ◽  
Vol 19 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Sampath Chandra Prasad ◽  
Enrico Piccirillo ◽  
Amjad Nuseir ◽  
Giuliano Sequino ◽  
Giuseppe De Donato ◽  
...  
Keyword(s):  
Skull Base ◽  
Giant Cell ◽  
Case Series ◽  
Base Case ◽  
Giant Cell Tumors

scholarly journals MALIGNANCY IN SOLITARY COLD NODULE THYROID

2016 ◽  
Vol 21 (4) ◽  
pp. 231
Author(s):  
Usman Habib Virk ◽  
Yar Muhammad ◽  
Khalid Masood Gondal ◽  
Humayun Siddique
Keyword(s):  
Local Population ◽  
Case Series ◽  
Sampling Technique ◽  
Clinical Problem ◽  
Clinical Findings ◽  
P Value ◽  
Endocrine Gland ◽  
Case Series Study ◽  
Palpable Nodule ◽  
Cold Nodule

AbstractIntroduction:The thyroid gland is one of the largest endocrine gland constitute of two lobes connected by an isthmus. Thyroid nodules are a frequent clinical problem and its incidence is rising. The solitary nodules are the palpable nodule in otherwise normal gland whereas dominant nodules are the palpable nodule in an enlarged gland. There is a variable frequency of malignancy in solitary cold nodule. Our study is aimed to find its frequency in local population.Objective:To determine the frequency of Maligna-ncy in solitary cold nodule thyroid.Material and Methods:This is the descriptive case series study conducted at East Surgical Ward, Mayo Hospital Lahore in 1 year duration from 01-01-2014 to 31-12-2014. 140 patients age more than 12 years of either sex with confirmed solitary cold nodule thyroid of any size on physical examination, ultrasound and thyroid scan through non-probability purposive sampling technique were included in the study. A biopsy of the cold nodule was sent to hospital laboratory to determine the frequency of malignancy. All demographic and clinical findings were recorded on a predesigned proforma. All collected data was entered and analyzed by using SPSS 20. Quantitative variables like age and size of nodule was presented in the form of mean SD and qualitative variables like gender and malignancy was presented in the form of frequency and percentages. Post-stratification chi-square test was applied, P-value ? 0.05 as significant.Results:The mean age of the patients was noted as 40.10 11.62 years. There were 47.14% male patients while 52.86% female. Malignancy was found in 23 (16.43%) patients whereas absent in 117 (83.57%) patients.Conclusion:It is concluded that the malignancy is more frequent in solitary cold nodule thyroid in our local population and in timely intervention and proper screening is recommended.Keywords:Malignancy, Cold Nodule Thyroid, Thy-roid Scan, Biopsy.

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