scholarly journals HAEMATOETIOLOGICAL EVALUATION OF SPLENOMEGALY

2020 ◽  
pp. 38-40
Author(s):  
Y.V.S. Prabhakar ◽  
Vasireddy Teja ◽  
Ponnaganti Vasundhara
Keyword(s):  
Case Series ◽  
Sampling Technique ◽  
Abdominal Ultrasound ◽  
Liver Function Tests ◽  
Clinical Findings ◽  
Haematological Parameters ◽  
Blood Picture ◽  
Additional Tool ◽  
Case Series Study ◽  
Series Study

BACKGROUND: Splenomegaly is usually the result of an underlying disorder.Causes ranging from infections to haematological malignancies. AIMS AND OBJECTIVES : Present study aims to find out the frequency of various haematological causes of splenomegaly and to study its haematological parameters . MATERIAL AND METHODS: This descriptive case series study was carried out at Department of Medicine at Nri General Hospital from 1st March 2019 to 31st August 2019,over a period of six months. 100 patients older than 13 years of age with clinically enlarged spleen were selected for this study. Sampling technique is Non propability convinient sampling. After getting informed consent from the patients proforma filled elaborating history, important clinical findings and investigations like abdominal ultrasound , complete blood picture , liver function tests , virals were performed. RESULTS: Males (57%) are most commonly affected than females (43%). The most common age group in males was 41-50 yrs and females was 21-30 yrs. The maximum cases were identified with moderate splenomegaly.Among the haematological causes 57% were leukemias,of which 30% were chronic and 27% were acute . CONCLUSION : Splenomegaly in a symptomatic person should always be investigated thoroughly as most of the cases are treatable. Haematological parameters with enlarged spleen is utmost important as an additional tool in evaluating the etiopathogenesis of splenomegaly.

scholarly journals ANTI-TUBERCULOSIS THERAPY

2018 ◽  
Vol 21 (04) ◽  
pp. 728-733
Author(s):  
Fardah Yunus Muhammad Khan ◽  
Rizwan Aziz Qazi ◽  
Muhammad Yunus Jadoon ◽  
Tausif Ahmed Rajput
Keyword(s):  
Case Series ◽  
General Medicine ◽  
Liver Function Tests ◽  
Effective Control ◽  
Medical Sciences ◽  
Biochemical Assays ◽  
Case Series Study ◽  
Genetic And Environmental Factors ◽  
Tuberculosis Therapy ◽  
Series Study

… Objectives: Tuberculosis (TB) is a major cause of illness and death worldwide,especially in Asia and Africa. An effective control has been achieved by the widespread use ofATT. It has been postulated that hepatotoxicity induced by ATT is not truly idiosyncratic inessence; rather certain genetic and environmental factors are attributed to coincide to producesufficient quantity of toxic metabolites that then cause varied alterations in liver functions.Objective of the study was to determine the frequency of derangement of liver enzymes inpatients taking anti-tuberculous therapy within the first 8 weeks of therapy. Study Design: Adescriptive case series study. Place and Duration of Study: The study was conducted at the inpatientand out-patient department of general medicine of Pakistan Institute of Medical Sciences(PIMS), Islamabad for blood sampling and biochemical assays. Material and Methods: Thestudy was performed on a total of 114 patients of tuberculosis. ATT was started after baseline liverfunction tests. Liver function tests were repeated at 4 weeks and 8 weeks to observe the effects onliver enzymes derangement. Results: 12 patients had deranged LFTs while 102 patients hadnormal LFTs after 4 weeks of treatment while 10 patients had deranged LFTs and 104 patients hadnormal LFTs after 8 weeks of treatment. Conclusions: Anti-tuberculosis drugs inducedhepatotoxicity occurs less frequently. All patients put on anti-tuberculous therapy must befollowed up for at least the initial 4 weeks, and the patient and caregivers should be told how torecognize signs of anti-tuberculous induced hepato-toxicity.

scholarly journals MALIGNANCY IN SOLITARY COLD NODULE THYROID

2016 ◽  
Vol 21 (4) ◽  
pp. 231
Author(s):  
Usman Habib Virk ◽  
Yar Muhammad ◽  
Khalid Masood Gondal ◽  
Humayun Siddique
Keyword(s):  
Local Population ◽  
Case Series ◽  
Sampling Technique ◽  
Clinical Problem ◽  
Clinical Findings ◽  
P Value ◽  
Endocrine Gland ◽  
Case Series Study ◽  
Palpable Nodule ◽  
Cold Nodule

AbstractIntroduction:The thyroid gland is one of the largest endocrine gland constitute of two lobes connected by an isthmus. Thyroid nodules are a frequent clinical problem and its incidence is rising. The solitary nodules are the palpable nodule in otherwise normal gland whereas dominant nodules are the palpable nodule in an enlarged gland. There is a variable frequency of malignancy in solitary cold nodule. Our study is aimed to find its frequency in local population.Objective:To determine the frequency of Maligna-ncy in solitary cold nodule thyroid.Material and Methods:This is the descriptive case series study conducted at East Surgical Ward, Mayo Hospital Lahore in 1 year duration from 01-01-2014 to 31-12-2014. 140 patients age more than 12 years of either sex with confirmed solitary cold nodule thyroid of any size on physical examination, ultrasound and thyroid scan through non-probability purposive sampling technique were included in the study. A biopsy of the cold nodule was sent to hospital laboratory to determine the frequency of malignancy. All demographic and clinical findings were recorded on a predesigned proforma. All collected data was entered and analyzed by using SPSS 20. Quantitative variables like age and size of nodule was presented in the form of mean SD and qualitative variables like gender and malignancy was presented in the form of frequency and percentages. Post-stratification chi-square test was applied, P-value ? 0.05 as significant.Results:The mean age of the patients was noted as 40.10 11.62 years. There were 47.14% male patients while 52.86% female. Malignancy was found in 23 (16.43%) patients whereas absent in 117 (83.57%) patients.Conclusion:It is concluded that the malignancy is more frequent in solitary cold nodule thyroid in our local population and in timely intervention and proper screening is recommended.Keywords:Malignancy, Cold Nodule Thyroid, Thy-roid Scan, Biopsy.

scholarly journals Comparison of Success Rate of Vaginal Birth after Cesarean Between Women with Lower Segment Uterine Scar Thickness more than and less than 3.5mm

2021 ◽  
Vol 15 (1) ◽  
pp. 17-20
Author(s):  
Robina Ali
Keyword(s):  
Cesarean Section ◽  
Case Series ◽  
Sampling Technique ◽  
Thickness Measurement ◽  
Vaginal Birth ◽  
Case Series Study ◽  
Group A ◽  
Uterine Scar ◽  
Group B ◽  
Series Study

Background: Although scar thickness is been used for predicting vaginal birth among women with previous one cesarean section but which women are good candidates for VBAC, the value of applying sonographic LUS thickness measurement in the management of VBAC remains unclear and there are no clear guidelines in this regard. Objective: To determine the frequency of successful vaginal birth after previous one cesarean section and to compare the frequency of vaginal birth after previous one cesarean section in women with scar thickness >3.5 mm compared to those with scar thickness ≤3.5 mm. Study Design: Descriptive, Case-series study. Settings: Department of Obstetrics & Gynecology, DHQ Hospital, Faisalabad. Duration: Six months from December 15, 2017 to June 15, 2018. Methodology: The Non probability, consecutive sampling technique was used in this study. A total of 151 patients in spontaneous labor at term presented to labor room and fulfilling the inclusion criteria were enrolled in this study. After taking informed written consent, the patients were placed randomly into two groups. Group A included all the women with scar thickness >3.5 mm on ultrasonography while Group B included all the women with scar thickness ≤ 3.5mm on ultrasonography. All cases were followed till delivery and outcome variables like vaginal birth was noted. Data was entered and analyzed through SPSS version 21. Results: Mean age was 27.53 ± 4.93 years. Mean gestational age was 39.09 ± 1.13 weeks. Frequency of successful vaginal birth after previous one cesarean section was found in 131(86.75%) patients, whereas there was no VBAC in 20(13.25%) patients. The results of the study showed that women with scar thickness > 3.5 mm were more likely to have vaginal birth (96.65%) versus those with scar thickness ≤3.5mm (79.27%) (P = 0.003). Conclusion: This study concluded that the frequency of vaginal birth after previous one cesarean section in women with scar thickness > 3.5 mm is much higher as compared to those with scar thickness ≤3.5mm.

Evaluating Vitality and Periodontal Sensitivity of Teeth Adjacent to the Site of Open Sinus Lift Surgery before and after Treatment: A Case Series Study

2020 ◽  
Vol 30 (2) ◽  
pp. 77-81
Author(s):  
Amir Moeintaghavi ◽  
Negar Azami ◽  
Mohammad Sadegh Zohrevand ◽  
Farid Shiezadeh ◽  
Hamid Jafarzadeh ◽  
...  
Keyword(s):  
Case Series ◽  
Sinus Lift ◽  
Case Series Study ◽  
Before And After ◽  
Series Study

Perfil microbiológico en los pacientes con diagnóstico de sinusitis nosocomial hospitalizados en la Unidad de Cuidados Intensivos del Hospital de San José durante el período de Febrero de 2013 a Marzo de 2015. Microbiological profile in patients diagnosed with nosocomial sinusitis hospitalized in the Intensive Care Unit of the Hospital of San Jose during the period February 2013 to March 2015.

2018 ◽  
Vol 45 (4) ◽  
pp. 261-266
Author(s):  
Jorge Luis Alfredo Herrera Ariza ◽  
Mario Alejandro Villabón ◽  
Ángela Carolina Rojas Ruiz ◽  
Iván Fernando Moncada
Keyword(s):  
Disease Control ◽  
Maxillary Sinus ◽  
Case Series ◽  
San Jose ◽  
Study Materials ◽  
Case Series Study ◽  
Nosocomial Sinusitis ◽  
Centers For Disease Control ◽  
Microbial Agents ◽  
Series Study

Objetivo: Determinar los agentes microbianos más frecuentes en pacientes de UCI con diagnóstico de sinusitis nosocomial en el Hospital de San José, período de dos años. Diseño: Estudio observacional tipo serie de casos. Materiales y métodos: Se incluyeron pacientes mayores de 18 años con una estancia hospitalaria mayor a 48 horas, que desarrollaron sinusitis nosocomial de acuerdo a los criterios de los Centers for Disease Control (CDC). Uso de dos técnicas: punción y lavado de seno maxilar. Resultados: 19 pacientes que cumplen los criterios de sinusitis nosocomial. Edad promedio 55 años, predominio sexo masculino. El 94.7% tuvo sonda orogástrica, 89.5% intubación orotraqueal y 89.5% ventilación mecánica. Hubo aislamiento polimicrobiano de gram positivos, gram negativos, anaerobios y hongos. La mortalidad en UCI fue 32%. Conclusiones: Se presenta una adecuada sensibilidad al tratamiento con vancomicina y piperacilina tazobactam en esta patología. El rendimiento diagnóstico es igual al realizar lavado y punción del seno maxilar.Objetive: To determine the microbial agents on UCI patients who have beendiagnosed with nosocomial sinusitis at the San Jose Hospital, (Bogota, Colombia) in a two-year period. Design: Case series study. Materials and methods: Patients who were older than 18-year olds, with a hospitalization longer than 48 hours who developed nosocomial sinusitis, according to the criteria established by the Centers for Disease Control (CDC) were included. Two techniques were employed for data collection: puncture and maxillary sinus wash. Results: 19 patients fulfill the criteria requirements for nosocomial sinusitis. Average age was 55 years old. Population mostly was composed by male individuals. 94.7% had a gastric tube intervention; 89.5% had tracheal intubation 89.5% mechanical ventilation. Polymicrobial isolation with gram positive, gram negative, anaerobic and fungi were identified. Mortality in critical care unites was 32%. Conclusions: An adequate sensitivity to treatment with vancomycin and piperacillin tazobactam was evidenced in this pathology.To perform a washing or maxillary sinus puncture had the same efficiency fordiagnosing this disease.

The case for skin camouflage in the management of upper limb scarring – A case series

Hand Therapy ◽  
2021 ◽  
pp. 175899832110078
Author(s):  
Laura Adamson ◽  
Anna Selby
Keyword(s):  
Upper Limb ◽  
Case Series ◽  
Primary Objective ◽  
Self Confidence ◽  
Published Evidence ◽  
Case Series Study ◽  
Visual Impact ◽  
Series Study ◽  
Increasing Function

Introduction For some people the appearance of their hands is as important as function. Upper limb scarring can cause some patients distress. Skin camouflage is an intervention that can be used to reduce the visual impact of a scar but there is limited published evidence for its use for hand scarring. Methods This is a case series study with a primary objective to determine whether skin camouflage reduces distress in patients with an upper limb scar and to evaluate this new service. Patients experiencing distress from an upper limb scar were recruited from a hand therapy outpatient clinic. The intervention delivered was a one hour skin camouflage session. Photographs of the upper limb pre and post skin camouflage intervention were taken. The patient-rated Michigan Hand Questionnaire (MHQ) and Derriford Appearance Scale (DAS24) were completed before treatment, at 1 week and 1 month after treatment. Results Six participants reporting distress from an upper limb scar received skin camouflage intervention. Only three out of six participants completed all follow-up. All three showed improvement in at least two domains of the MHQ (function and aesthetics) at one month post treatment. Increased confidence during functional and work-based activities was also reported on the DAS24. Participants reported increased engagement in daily activities as a result of being able to camouflage their scars. Conclusions This small case series shows that skin camouflage intervention may be beneficial for some patients who are experiencing distress related to an upper limb scar by increasing function and self-confidence.

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