scholarly journals TO THE HYDRAULIC CALCULATION OF PRESSURE DRAINAGE PIPELINES, OPERATING IN DISTRIBUTION REGIME

2021 ◽  
Vol 3 (163) ◽  
pp. 68-74
Author(s):  
O. Kravchuk

A system of two differential equations which describes the movement of fluid in a pipe with a variable flow rate and the conditions for the fluid outflow through the walls of drainage pipelines into the surrounding soil is considered. It is reasoned that the second term in the original equation, which takes into account energy losses associated with a flow rate variation along the length, can be neglected without a substantial error. The considered system is reduced to dimensionless form by introducing original variables. The coefficient of collecting drainage pipeline resistance «ζl» and the generalized parameter «A», which take into account the structural and hydraulic characteristics of the considered flow, are two main parameters used in the analysis. The concept of an infinitely long drainage pipeline (a pipeline with an infinite walls filtration capacity) is introduced in the article. Also it is noted that such pipeline will have a maximum throughput comparing to pipes of the same diameter but limited length. Quite simple and practical calculated dependencies for the determination of the nature of flow rate variation and pressure drop along the length of the pipeline were received on the basis of the conducted analysis. Important characteristics of pressure distribution pipelines were calculated on the basis of offered formulas. Corresponding graphical dependencies were built for visibility. In particular, graphs of the flow rate variation at the end of the distributor, depending on the design and filtration characteristics of the «soil-drain» system, are presented. Graph that shows the dependence of the variation in the flow rate distribution unevenness along the length of the drainage pipe at various ​​hydraulic conductivity values of the surrounding soil is important for understanding the drainage pipelines particularity. The necessity to take into account the nature of the flow rate connection unevenness along the length for obtaining reliable results for real drainage pipelines calculation is demonstrated.

Author(s):  
O.A. Kravchuk ◽  

A system of two differential equations, which describes the fluid motion in a pipe with a variable flow rate and the conditions for fluid entry through the drainage pipelines walls from the surrounding soil, is considered. It is shown that for the studied case the second term in the original equation can be neglected without a significant error. The system is reduced to a dimensionless form by introducing the original variables. The solution of this equations system is given in a dimensionless form. Two main parameters are used in the analysis: the coefficient of collecting drainage pipeline resistance "ζl" and the generalized parameter "A", which takes into account the structural and hydraulic characteristics of the considered flow. Also, the concept of an infinitely long drainage pipeline or, which is the same, a pipeline with an infinite walls filtration capacity of the drainage pipeline is introduced in the article. It is noted that such pipeline will have a maximum throughput compared to pipes of the same diameter but limited length. Sufficiently simple and convenient calculated dependencies for the determination of the nature of flow rate variation and pressure drop along the length of the pipeline were obtained on the basis of the conducted analysis. Series of calculations of important characteristics for such pipes were carried out on the basis of offered formulas. Corresponding graphical dependencies were built for visibility. In particular, graphs of the flow rate variations at the end of the collector, depending on the design and filtration characteristics of the “soil-drain” system, are presented. Graph, that shows the dependence of the change in the flow rate connection unevenness along the length of the drainage pipeline at various hydraulic conductivity values of the surrounding soil, is important for understanding the drainage pipes particularity. The necessity to take into account the nature of the flow rate connection unevenness along the length for obtaining reliable results when calculating real drainage pipelines is shown in the article.


Author(s):  
V. M. Borishansky ◽  
A.A. Andreevsky ◽  
Mikhail Ya. Belenkiy ◽  
G.S Bykov ◽  
Mikhail Gotovskii ◽  
...  
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2018 ◽  
Vol 15 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Bürge Aşçı ◽  
Mesut Koç

Introduction:This paper presents the development and validation of a novel, fast, sensitive and accurate high performance liquid chromatography (HPLC) method for the simultaneous quantitative determination of dibucaine HCl, fluocortolone pivalate and fluocortolone caproate in pharmaceutical preparations.Experiment:Development of the chromatographic method was based on an experimental design approach. A five-level-three-factor central composite design requiring 20 experiments in this optimization study was performed in order to evaluate the effects of three independent variances including mobile phase ratio, flow rate and amount of acid in the mobile phase.Conclusion:The optimum composition for mobile phase was found as a methanol:water:acetic acid mixture at 71.6 : 26.4 : 2 (v/v/v) ratio and optimum separation was acquired by isocratic elution with a flow rate of 1.3 mL/min. The analytes were detected using a UV detector at 240 nm. The developed method was validated in terms of linearity, precision, accuracy, limit of detection/quantitation and solution stability and successfully applied to the determination of dibucaine HCl, fluocortolone pivalate and fluocortolone caproate in pharmaceutical topical formulations such as suppositories and ointments.


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