scholarly journals Clinicopathological and Incidence Analysis of Malignant Salivary Gland Tumours: A 16-year Retrospective Study in the North of Portugal

Objectives: A) Evaluate the clinical-pathological characteristics of malignant neoplasms of salivary glands: A.1) Quantify the numbers of which tumor subtype. A.2) Gender, age and the type of salivary gland influence tumor behavior? A.3) Describe 16 years of evolution in a target portuguese population. B) What are the treatments chosen in which subtype? C) What is the prognosis? And what can influence the prognosis? Study Design: A 16-year retrospective study of 138 patients with salivary gland tumors from 2000 to 2016 in the Anatomical Pathology Department of Centro Hospitalar do Porto, Hospital Geral de Santo António. The histological diagnoses - according to the 2017 World Health Organization classification. Results: In the present study, we revised all the cases of salivary gland pathology from 396 cases. A total of 138 tumors were identified in 91 male and 47 female patients. The mean age was 58 years. The frequency of major salivary gland tumors was 56.3%, and that of minor salivary gland tumors was 43.7%. Mucoepidermoid carcinoma was the most common malignant tumor. Conclusions: Knowledge of the different clinic characteristics is important and essential to a better prognosis and in many cases a reduction of the mortality.

2016 ◽  
Vol 15 (1) ◽  
pp. 95-98
Author(s):  
Afroza Khanam ◽  
Gulshan Akhter ◽  
Md. Abdur Rahman

Background: Salivary gland tumors are rare, generally benign and affect both major and minor salivary glands.Objective: To find out the pattern of distribution of different benign and malignant salivary gland epithelial tumors and their relation to age and sex in a tertiary care center in Bangladesh.Methodology: This is a retrospective study. Details of epithelial salivary gland tumors were obtained from department of ENT, National institute of cancer & research hospital (NICRH), Dhaka, Bangladesh from the period January 2009 to December 2012 (3 years).Result: A total number of 261 cases presenting with both benign and malignant salivary gland tumors were analyzed according to gender, age and histopathological findings. There were 130 (49.84%) males and 131 (50.19%) females with the male female ration of 1: 0.99. Age of study population ranged from 10 to 70 years with the mean age 40.78. Percentage of benign salivary gland tumors was 73.94% and malignant salivary gland tumor 26.05%. Among major salivary gland tumors, no sublingual tumors were found and parotid gland tumors were the commonest. Whereas, among minor salivary gland tumors palatal minor salivary tumors were common.Conclusion: Parotid gland was the most common site of origin of both benign and malignant salivary gland tumors. Histopathologically, pleomorphic adenoma was the most common benign salivary gland tumor and mucoepidermoid carcinoma was the most frequent malignant neoplasm. Adenoid cystic carcinoma was common minor salivary gland tumor.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.90-94


2010 ◽  
Vol 14 (4) ◽  
pp. 203-209 ◽  
Author(s):  
Astrid L. D. Kruse ◽  
Klaus W. Grätz ◽  
Joachim A. Obwegeser ◽  
Heinz-Theo Lübbers

1997 ◽  
Vol 39 (3) ◽  
pp. 128-132 ◽  
Author(s):  
Kaoru Kusama ◽  
Shinkichi Iwanari ◽  
Kunio Aisaki ◽  
Masahiko Wada ◽  
Jun Ohtani ◽  
...  

Author(s):  
Sasmita Panda ◽  
Subrat Kumar Samantara ◽  
Paresh Kumar Behera ◽  
Sashibhusan Dash ◽  
Sagarika Samantaray

Introduction: Regional record is a useful strategy for the analysis of the clinicohistopathological presentation of Salivary Gland Tumours (SGTs) in a specific population by which appropriate management can be established. Aim: To investigate the clinicohistopathological presentation of SGTs in a tertiary care cancer centre, Odisha, India. Materials and Methods: This single centre hospital based cross-sectional study was carried in Acharya Harihar Post-Graduate Institute of Cancer, Cuttack, Odisha, India. Five years (from January 2015 to December 2019) clinical and histopathological data of SGTs were retrieved from hospital record section. The data collection and analysis was done from January 2019 to December 2020. The SGTs cases were classified under the histological criteria suggested by the World Health Organisation (WHO) in 2017. Count data were expressed as percentages and differences between the groups were compared using the Chi-square test. The results were analysed using Statistical Package for the Social Sciences (SPSS) computer software version 17.0. Results: A total of 319 neoplastic SGTs were included out of which malignant tumours were comprised of 144 (45.14%). Mucoepidermoid Carcinoma (MEC) was the most common malignant type while Pleomorphic Adenomas (PA) was reported as the most common benign type. The mean±SD age of the patients with benign and malignant tumour was 41.94±13.94 years and 46.09±13.33 years, respectively. The percentage of malignant neoplasms in the minor salivary gland was higher (37/60, 61.66%) than benign tumours. while in major salivary glands, it was found (107/259, 41.31%). In major salivary gland, greater involvement of the parotid gland was observed. The mean tumour size of the major SGT was 3.34±1.09 cm wereas the mean tumour size of the minor salivary gland was 2.35±1.26 cm. Conclusion: The PA and MEC were the most common benign and malignant types respectively. The knowledge regarding histopathological presentation of SGTs in present study would help to pathologist and surgeons for more accurate diagnosis and further management. As, the preoperative diagnosis of SGTs is very challenging,further study in this regard is needed.


2019 ◽  
Author(s):  
Sina Torabi ◽  
Todd Spock ◽  
Bruno Cardoso ◽  
Janet Chao ◽  
R. Manes ◽  
...  

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