scholarly journals Pattern of distribution of different salivary gland tumors; a retrospective study in NICRH, Dhaka

2016 ◽  
Vol 15 (1) ◽  
pp. 95-98
Author(s):  
Afroza Khanam ◽  
Gulshan Akhter ◽  
Md. Abdur Rahman

Background: Salivary gland tumors are rare, generally benign and affect both major and minor salivary glands.Objective: To find out the pattern of distribution of different benign and malignant salivary gland epithelial tumors and their relation to age and sex in a tertiary care center in Bangladesh.Methodology: This is a retrospective study. Details of epithelial salivary gland tumors were obtained from department of ENT, National institute of cancer & research hospital (NICRH), Dhaka, Bangladesh from the period January 2009 to December 2012 (3 years).Result: A total number of 261 cases presenting with both benign and malignant salivary gland tumors were analyzed according to gender, age and histopathological findings. There were 130 (49.84%) males and 131 (50.19%) females with the male female ration of 1: 0.99. Age of study population ranged from 10 to 70 years with the mean age 40.78. Percentage of benign salivary gland tumors was 73.94% and malignant salivary gland tumor 26.05%. Among major salivary gland tumors, no sublingual tumors were found and parotid gland tumors were the commonest. Whereas, among minor salivary gland tumors palatal minor salivary tumors were common.Conclusion: Parotid gland was the most common site of origin of both benign and malignant salivary gland tumors. Histopathologically, pleomorphic adenoma was the most common benign salivary gland tumor and mucoepidermoid carcinoma was the most frequent malignant neoplasm. Adenoid cystic carcinoma was common minor salivary gland tumor.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.90-94

Objectives: A) Evaluate the clinical-pathological characteristics of malignant neoplasms of salivary glands: A.1) Quantify the numbers of which tumor subtype. A.2) Gender, age and the type of salivary gland influence tumor behavior? A.3) Describe 16 years of evolution in a target portuguese population. B) What are the treatments chosen in which subtype? C) What is the prognosis? And what can influence the prognosis? Study Design: A 16-year retrospective study of 138 patients with salivary gland tumors from 2000 to 2016 in the Anatomical Pathology Department of Centro Hospitalar do Porto, Hospital Geral de Santo António. The histological diagnoses - according to the 2017 World Health Organization classification. Results: In the present study, we revised all the cases of salivary gland pathology from 396 cases. A total of 138 tumors were identified in 91 male and 47 female patients. The mean age was 58 years. The frequency of major salivary gland tumors was 56.3%, and that of minor salivary gland tumors was 43.7%. Mucoepidermoid carcinoma was the most common malignant tumor. Conclusions: Knowledge of the different clinic characteristics is important and essential to a better prognosis and in many cases a reduction of the mortality.


2018 ◽  
Vol 6 ◽  
pp. 2050313X1881871 ◽  
Author(s):  
Nicole Diaz-Segarra ◽  
Lauren K Young ◽  
Kristin Levin ◽  
William Rafferty ◽  
Joshua Brody ◽  
...  

Warthin tumor is the second most common benign salivary gland tumor that classically arises in the parotid gland. It can be synchronous, metachronous, multifocal, bilateral, or unilateral, which complicates diagnosis and management. Rare cases of Warthin tumor of the minor salivary gland are described, but no cases of unilateral, synchronous Warthin tumor involving the parotid and minor salivary gland have been reported. We present a case of Warthin tumor arising from a minor salivary gland in the left oropharynx of a 71-year-old male with a previous history of left parotid Warthin tumor, later determined to be synchronous.


2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.


2010 ◽  
Vol 14 (4) ◽  
pp. 203-209 ◽  
Author(s):  
Astrid L. D. Kruse ◽  
Klaus W. Grätz ◽  
Joachim A. Obwegeser ◽  
Heinz-Theo Lübbers

1997 ◽  
Vol 39 (3) ◽  
pp. 128-132 ◽  
Author(s):  
Kaoru Kusama ◽  
Shinkichi Iwanari ◽  
Kunio Aisaki ◽  
Masahiko Wada ◽  
Jun Ohtani ◽  
...  

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