scholarly journals Hypermnesia of Euphoria or Any Other Desired, from the Point of View of the Consumer, Psychotropic Effect as the Initial and leading link in the Occurrence and Maintaining the Body’s Dependence on Psychoactive Factors

2018 ◽  
Vol 2 (2) ◽  

The work shows the role of the autonomic nervous system in functioning of long-term memory, the identity of functioning of the mechanisms of long-term memory in the evolutionary adaptation of a man and dependence on psychoactive substances. It is shown that the dependences of the body on psychoactive substances are the states of progredient adaptation, that the states of dependence of the organism on psychoactive substances and on psychogenic psychoactive factors are the states of the same type. Classification of psychoactive factors is given. It is proposed to create a new branch of medicine combining study of the body’s dependence both on chemical and psychogenic psychoactive factors. Onomastic definitions to be used in this new branch of medicine are presented.

Author(s):  
D G Baitubayev ◽  
M D Baitubayeva

The work shows the role of the vegetative nervous system (VNS) in the functioning of long-term memory, identity mechanisms of long-term memory in the human evolutionary adaptation and substance dependence. It is shown that, depending on the substance of the body are states like pro- gressive adaptation, that the bodycondition, depending on the chemical and psychogenic psychoactive- factors state of the same circle. It proposed the creation of a branch of medicine that combines study of the dependence of the organism, both on the chemical and psychoactive psychogenic factors. Given the classification of psychoactive factors.Onomastics formulated definitions of terminology changes and additions to be used in a new branch of medicine. Proposed allocation of the International Classifica- tion of diseases separate chapter for the classification of states like progressive adaptation of the body depending on psychoactive factors.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hamish Patel ◽  
Reza Zamani

Abstract Long-term memories are thought to be stored in neurones and synapses that undergo physical changes, such as long-term potentiation (LTP), and these changes can be maintained for long periods of time. A candidate enzyme for the maintenance of LTP is protein kinase M zeta (PKMζ), a constitutively active protein kinase C isoform that is elevated during LTP and long-term memory maintenance. This paper reviews the evidence and controversies surrounding the role of PKMζ in the maintenance of long-term memory. PKMζ maintains synaptic potentiation by preventing AMPA receptor endocytosis and promoting stabilisation of dendritic spine growth. Inhibition of PKMζ, with zeta-inhibitory peptide (ZIP), can reverse LTP and impair established long-term memories. However, a deficit of memory retrieval cannot be ruled out. Furthermore, ZIP, and in high enough doses the control peptide scrambled ZIP, was recently shown to be neurotoxic, which may explain some of the effects of ZIP on memory impairment. PKMζ knockout mice show normal learning and memory. However, this is likely due to compensation by protein-kinase C iota/lambda (PKCι/λ), which is normally responsible for induction of LTP. It is not clear how, or if, this compensatory mechanism is activated under normal conditions. Future research should utilise inducible PKMζ knockdown in adult rodents to investigate whether PKMζ maintains memory in specific parts of the brain, or if it represents a global memory maintenance molecule. These insights may inform future therapeutic targets for disorders of memory loss.


2001 ◽  
Vol 92 (1) ◽  
pp. 223-233
Author(s):  
D. P. McCabe ◽  
D. I. Ben-Tovim ◽  
M. K. Walker ◽  
D. Pomeroy

Do the mental Images of 3-dimensional objects recreate the depth characteristics of the original objects' This investigation of the characteristics of mental images utilized a novel boundary-detection task that required participants to relate a pair of crosses to the boundary of an image mentally projected onto a computer screen. 48 female participants with body attitudes within expected normal range were asked to image their own body and a familiar object from the front and the side. When the visual mental image was derived purely from long-term memory, accuracy was better than chance for the front (64%) and side (63%) of the body and also for the front (55%) and side (68%) of the familiar nonbody object. This suggests that mental images containing depth and spatial information may be generated from information held in long-term memory. Pictorial exposure to views of the front or side of the objects was used to investigate the representations from which this 3-dimensional shape and size information is derived. The results are discussed in terms of three possible representational formats and argue that a front-view 2½-dimensional representation mediates the transfer of information from long-term memory when depth information about the body is required.


2020 ◽  
Author(s):  
Bank G. Fenyves ◽  
Andreas Arnold ◽  
Vaibhav G. Gharat ◽  
Carmen Haab ◽  
Kiril Tishinov ◽  
...  

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