scholarly journals Biometry for the Management of Angle Closure in Young patients

2017 ◽  
Vol 1 (1) ◽  

Importance: To describe the clinical and biometric features in patients with angle closure presenting before the age of 40 years. Observations: We describe three young patients with angle closure and a customized treatment plan for each guided by the biometric findings, axial length (AL), keratometry, ACD, Lens Thickness, Lens Vault and LT/AL ratio. We found that lens thickness to axial length ratio of >0.2 may suggest the need for clear lens extraction in these cases for better IOP control. Conclusions and relevance: Biometry plays a pivotal role in elucidating the etiopathogenesis and management of angle closure in young patients, and should be included in the evaluation of such patients.

2019 ◽  
Author(s):  
Xiaoli Xing ◽  
Liangyu Huang ◽  
Fang Tian ◽  
Yan Zhang ◽  
Yingjuan Lv ◽  
...  

Abstract Background: To compare the anterior biometry of eyes with secondary acute angle closure induced by occult lens subluxation (LS), misdiagnosed as acute primary angle closure (APAC) at the first visit, APAC, chronic primary angle closure glaucoma (CPACG), cataract. Methods: This retrospective case study included 17 eyes with PAC due to occult LS, who were misdiagnosed as APAC on their first visit, 56 eyes diagnosed as APAC, 54 eyes diagnosed as CPACG, and 56 eyes diagnosed as cataract. Axial length (AL), Central corneal thickness (CCT), anterior chamber depth (ACD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test. Results: The patients in the LS group had a longer ocular axial length than those with acute angle closure and CPACG. Corneal thickness in the LS group was not significantly different from that in the APAC group, but was significantly different from those of the CPACG and cataract group. The APAC group had the smallest ACD, while the LS group had the smallest AD. The LS group exhibited significantly shallower ACD (P<0.01). The LS group had the largest lens thickness. Conclusions: This study revealed that LS secondary PAC patients had a shallower ACD, thicker CCT and lens thickness comparing to those of APAC, CPACG and cataract patients. A short depth (< 1.25 mm) and a thick lens thickness (> 5.13 mm) are crisis of lens subluxation in our data. LP and CLP can be helpful for differential diagnosis. Trial registration: NCT03752710, retrospectively registered.


2015 ◽  
Vol 74 (1) ◽  
Author(s):  
Khathutshelo P. Mashige

Aim: The reliability of an instrument used to collect data for clinical and research purposes is greatly important, especially when it is used to determine changes in measured ocular parameters over time. The purpose of this study was to determine the intra-session repeatability and inter-session reproducibility of axial length (AL), anterior chamber depth (ACD) and crystalline lens thickness (LT) measurements using the Nidek US-500 Echoscan.Method: Fifty successive automatic measurements of the above parameters were taken on the right eyes only of 12 healthy subjects aged 23–44 years old, followed by similar repeated measures after 1 week. Sample standard deviations (s.d.), precision (P) and coefficient of repeatability (COR) were calculated to determine intra-session repeatability. Coefficient of reproducibility (CRP), Bland and Altman plots, concordance correlation coefficients (CCC) and paired t-tests that compared measurements obtained in the first and second sessions, were used to determine inter-session reproducibility.Results: Both the intra-session repeatability and inter-session reproducibility were within acceptable limits for the three variables assessed.Conclusion: The study showed that the Nidek US-500 Echoscan provides accurate, repeatable and reproducible measurements of AL, ACD and LT in healthy eyes. This finding will be of interest to optometrists and ophthalmologists who measure these parameters when diagnosing, managing and investigating conditions such as primary angle-closure glaucoma and keratoconus.


2019 ◽  
Author(s):  
Xiaoli Xing ◽  
Liangyu Huang ◽  
Fang Tian ◽  
Yan Zhang ◽  
Yingjuan Lv ◽  
...  

Abstract Background : To compare the anterior biometry of eyes with secondary acute angle closure induced by occult lens subluxation (LS), misdiagnosed as acute primary angle closure (APAC) (ASAC-LS ) at the first visit, APAC, chronic primary angle closure glaucoma (CPACG), cataract. Methods : This retrospective case study included 17 eyes with primary angel closure(PAC)due to occult LS, who were misdiagnosed as APAC on their first visit, 56 eyes diagnosed as APAC, 54 eyes diagnosed as CPACG, and 56 eyes diagnosed as cataract. Axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD) , aqueous depth (AD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test. Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cutoff value of ocular biometry. Results: The patients in the ASAC-LS group had a longer ocular axial length than those with acute angle closure and CPACG. Corneal thickness in the ASAC-LS group was not significantly different from that in the APAC group, but was significantly different from those of the CPACG and cataract group. The APAC group had the smallest ACD, while the ASAC-LS group had the smallest AD. The ASAC-LS group exhibited significantly shallower AD (P<0.01). The ASAC-LS group had the largest lens thickness. According to ROC curve analysis,RLP, ACD, AD, LP, CLP, CCT were high power of discrimination. Conclusions: This study revealed that LS secondary PAC patients had a shallower AD, thicker CCT comparing to those of APAC, CPACG and cataract patients. LP and CLP can be helpful for differential diagnosis.


2019 ◽  
Author(s):  
Xiaoli Xing ◽  
Liangyu Huang ◽  
Fang Tian ◽  
Yan Zhang ◽  
Yingjuan Lv ◽  
...  

Abstract Background : To compare the anterior biometricsof eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), which were misdiagnosed at the first visit withacute primary angle closure (APAC), chronic primary angle closure glaucoma (CPACG), or cataracts. Methods: This retrospective case series ncluded 17 eyes with angle closure due to occult LS which were misdiagnosed with APAC at the first visit, 56 APACeyes, 54 CPACGeyes, and 56 cataracteyes. The axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth (AD), and lens thickness (LT) were recorded. The lens position (LP), relative lens position (RLP), and corrected lens position (CLP) were calculated. Quantitative data were subject to a one-way analysis of variance and correlation analysis. Categorical data were analysed using the chi-squared test. Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cut-off value for ocular biometrics. Results: The ASAC-LSpatients had a longer ocular AL than the APACand CPACGpatients. The CCTinthe ASAC-LS patientsdid not significantly differ from that in the APAC patientsbut did significantly differ from that of the CPACG and cataract patients.The APAC patientshad the smallest ACD, while the ASAC-LS patientshad the smallest AD. The ASAC-LS patientshad the thickest lenses. According to the ROC curve analysis, the RLP, ACD, AD, CLP, and LP hada high power of discrimination. Conclusions: This study revealed that ASAC-LS patients had a shallower AD and thicker CCT compared to APAC, CPACG, and cataract patients. Biometric parameters ACD, ADwere characteristic of lens subluxation according to our data. The calculated parameters RLP,CLP, LP can be helpful in the differential diagnosis between ASAC-LSand APAC, CPACG, Cataract. Trial registration: NCT03752710, retrospectively registered. Keywords:Lens subluxation; Acute angle-closure; Biometry; Anterior chamber depth; Lens thickness; Axial length


2019 ◽  
Author(s):  
Xiaoli Xing ◽  
Liangyu Huang ◽  
Yan Zhang ◽  
Yingjuan Lv ◽  
Wei Liu ◽  
...  

Abstract Background: To compare the anterior biometry of eyes with secondary acute angle closure induced by occult lens subluxation (LS), misdiagnosed as acute primary angle closure (APAC) at the first visit, APAC, chronic primary angle closure glaucoma (CPACG), cataract. Methods: This retrospective case study included 17 eyes with PAC due to occult LS, who were misdiagnosed as APAC on their first visit, 56 eyes diagnosed as APAC, 54 eyes diagnosed as CPACG, and 56 eyes diagnosed as cataract. Axial length (AL), Central corneal thickness (CCT), anterior chamber depth (ACD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test. Results: The patients in the LS group had a longer ocular axial length than those with acute angle closure and CPACG. Corneal thickness in the LS group was not significantly different from that in the APAC group, but was significantly different from those of the CPACG and cataract group. The APAC group had the smallest ACD, while the LS group had the smallest AD. The LS group exhibited significantly shallower ACD (P<0.01). The LS group had the largest lens thickness. Conclusions: This study revealed that LS secondary PAC patients had a shallower ACD, thicker CCT and lens thickness comparing to those of APAC, CPACG and cataract patients. A short depth (< 1.25 mm) and a thick lens thickness (> 5.13 mm) are crisis of lens subluxation in our data. LP and CLP can be helpful for differential diagnosis. Trial registration: NCT03752710, retrospectively registered.


2020 ◽  
Author(s):  
Xiaoli Xing ◽  
Liangyu Huang ◽  
Fang Tian ◽  
Yan Zhang ◽  
Yingjuan Lv ◽  
...  

Abstract Background: To compare the anterior biometrics of eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chronic primary angle closure glaucoma (CPACG), and cataract. Methods : This retrospective case study included 17 eyes with angel closure due to occult LS, who were misdiagnosed as APAC on their first visit, 56 APAC eyes, 54 CPACG eyes, and 56 cataract eyes. Axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD) , aqueous depth (AD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test.Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cutoff value of ocular biometrics. Results: The ASAC-LS patients had a longer ocular axial length than APACand CPACGpatients. Central corneal thickness ofthe ASAC-LSpatientswas not significantly different from APAC patients, but was significantly different from CPACG and cataract patients. The APAC patientshad the smallest ACD, while the ASAC-LS patientshad the smallest AD. The ASAC-LS patientshad the largest lens thickness. According to ROC curve analysis, RLP, ACD, AD, CLP, LP hadhigh power of discrimination. Conclusions: This study revealed that LS secondary PAC patients had a shallower AD, thicker CCT comparing to those of APAC, CPACG and cataract patients.LP and CLP can be helpful for differential diagnosis. Trial registration: NCT03752710, retrospectively registered. Keywords: Lens subluxation; Acute angle-closure; Biometry; Anterior chamber depth; Lens thickness; Axial length


2021 ◽  
Vol 14 (5) ◽  
pp. 714-718
Author(s):  
Ya-Meng Liu ◽  
◽  
Long-Fang Zhou ◽  
Jie Lan ◽  
Cheng-Cheng Feng ◽  
...  

AIM: To investigate the association of axial length (AL), lens thickness (LT), and lens vault (LV) with postoperative anterior chamber angle metrics after laser peripheral iridotomy (LPI). METHODS: Prospective observational study of 69 patients (97 eyes) were diagnosed as primary angle-closure suspect (PACS), primary angle closure (PAC) or primary angle-closure glaucoma (PACG). AL, LT, anterior central chamber depth (ACD), angle opening distance (AOD), trabecular iris angle (TIA), and angle recess area (ARA) were measured before and 1wk after LPI. The association between AL, LT, LV with ACD, AOD, TIA, ARA were analyzed by comparing the differences between preoperative and postoperative measurements for anterior segment biometric parameters. RESULTS: ACD, AOD, TIA, and ARA were significantly increased after LPI (all P&#x003C;0.05). Greater LT was significantly associated with greater postoperative increases in ACD, AOD, TIA, and ARA (all P&#x003C;0.05). AL was not significantly associated with changes of anterior segment biometric parameters. Greater LV was significantly associated with greater postoperative increases in ACD, AOD, and TIA (all P&#x003C;0.05), but was not significantly associated with changes of ARA. CONCLUSION: Greater baseline LT and LV measurements are associated with greater increases in anterior segment biometric parameters after laser peripheral iridotomy. AL are not associated with the change of anterior segment biometric parameters.


2017 ◽  
Vol 74 (10) ◽  
pp. 932-939
Author(s):  
Zorka Grgic ◽  
Ana Oros ◽  
Jelena Karadzic ◽  
Vladimir Canadanovic ◽  
Sandra Jovanovic ◽  
...  

Background/Aim. Preterm birth and retinopathy of prematurity (ROP) could affect optical and biometric features of eyes and cause refractive errors. The aim of this study was to compare the ocular axial length, anterior chamber depth and lens thickness changes during the first year in preterm born babies with and without ROP. Methods. This prospective longitudinal study included 87 preterm born babies. The examinations were performed at 3 and 12 months after birth and included fundus examination and measurements of the ocular axial length, anterior chamber depth and lens thickness. Based on the results of fundus examination at 3 months, the subjects were divided into two groups and the measurements of those with and without ROP were compared. Results. At 3 months 60.92% of infants had ROP. The mean values in the ROP group were: axial length 16.56 mm and 16.53 mm, chamber depth 2.34 mm and 2.38 mm and lens thickness 4.04 mm and 3.96 mm, in the right and the left eye, respectively. In the no ROP group these values were: axial length 17.06 mm and 17.08 mm, chamber depth 2.31mm and 2.39 mm and lens thickness 4.16 mm and 4.14 mm in the right and the left eye, respectively. At 12 months 28.74% of the children had a change in the ocular fundus as a result of the ROP therapy. In the ROP group the axial length was 19.94 mm in both eyes, chamber depth 3.01 mm and 2.99 mm and lens thickness 4.28 mm and 4.29 mm, in the right and the left eye, respectively. In the no ROP group the axial length was 20.64 mm and 20.29 mm, lens thickness 4.37 mm and 4.36 mm, in the right and the left eye, respectively and chamber depth 3.10 mm in both eyes. Conclusion. In the group of children with ROP axial length of the eye at 3 and 12 months was statistically significantly smaller in comparison to the group without ROP. Statistically significant difference was not found between these groups in the anterior chamber depth and lens thickness.


2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Syed Shoeb Ahmad

The lens appears to play a strategic role in the etiopathogenesis of glaucoma. This is not a new concept. In 1891 Priestley Smith had noted that some patients diagnosed with glaucoma demonstrated shallow anterior chambers even before the development of the disease (glaucoma). He concluded that this feature could be attributed to the disproportion between the size of the eyeball and the lens1. Lowe (1969) mentioned that the anatomical basis of primary angle closure glaucoma (PACG) lies in two important “constitutional” factors (lens position and thickness) and two other factors of lesser importance related to advanced age (increase in lens thickness and anterior lens displacement)2.


Sign in / Sign up

Export Citation Format

Share Document