scholarly journals Obsessive-Compulsive Disorder: Diagnosis and Management with an Osteopathic Component

2020 ◽  
pp. 18-24
Author(s):  
Theodore Flaum ◽  
Ravi Chinsky ◽  
Sheldon Yao

Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric disorder that affects about one in 40 American adults and one in 100 American children. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the patient must have the presence of obsessions, compulsions or both. OCD can be covert in presentation and therefore requires physician vigilance with the diagnosis. The efficacy of the physician’s interviewing style is extremely important in OCD treatment because typically, long delays in diagnosis often occur and the shame associated with the disorder may inhibit discussion of the symptoms and treatment plans. In addition to serotonin-regulating medications, deciphering the etiology of the patient’s obsessions or compulsions is important. Thus, cognitive behavioral therapy supplemented with SSRIs is the true first-line therapy for OCD because it provides a synergistic approach of life discussions, habit training and medication. Because of the inseparability of physical and mental health, osteopathic medicine offers an effective model for treatment through osteopathic manipulative treatment (OMT). In the holistic view of OMT, somatic, visceral and psychological dysfunctions are united. Thus, physicians who incorporate OMT into their practice can aid in the treatment of psychopathology, such as OCD. In this article, we will discuss the epidemiology of OCD, the DSM-5 criteria for OCD, the current OCD treatments, the osteopathic approach and how it pertains to OCD treatment, and lastly, OMT and its possible role in treating OCD. Due to a lack of research on osteopathic manipulative medicine (OMM) treatments in OCD, we will also propose a possible study design for further investigation.

2021 ◽  
Vol 7 (1) ◽  
pp. 1-10
Author(s):  
Tarrinni Inastyarikusuma

Pendahuluan: Obsessive-compulsive disorder (OCD) merupakan gangguan neuropsikiatri yang menyulitkan, menyita waktu, atau mengganggu secara substantial. OCD pediatrik terjadi pada 1-2% anak-anak dan remaja. Hal tersebut ditandai dengan adanya obsesi dan kompulsi berulang yang menimbulkan bahaya dan mengganggu kehidupan sehari-hari. OCD pediatrik dikaitkan dengan peningkatan risiko gangguan psikiatri lainnya di masa dewasa. Pada OCD onset anak, anak laki-laki lebih sering terkena OCD dibanding anak perempuan (rasio laki-laki:perempuan, 2:1 hingga 3:1), sedangkan rasio jenis kelamin bergeser hingga masa setelah pubertas dengan perbandingan laki- laki:perempuan 1: 1,4. Pembahasan: Terdapat beberapa teori yang dinyatakan sebagai penyebab OCD, yaitu disfungsi ganglia basalis, kelainan neurotransmitter, dan disfungsi neuroimun. Penilaian gejala OCD dapat dilakukan menggunakan berbagai alat, tetapi alat yang lebih sering digunakan adalah SOCS dan untuk diagnosis tetap berpedoman pada ICD-10 dan DSM- 5. Kesimpulan: Menurut terapi berbasis bukti, pengobatan pada OCD pediatrik yang terbaik adalah dengan cognitive behavioral therapy (CBT) dan SRI/SSRI. Kata Kunci: cognitive behavioral therapy, obsessive-compulsive disorder, pediatrik, remaja


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alexandre Vallée ◽  
Jean-Noël Vallée ◽  
Yves Lecarpentier

AbstractObsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear. Recent findings have shown that oxidative stress, inflammation, and the glutamatergic pathway play key roles in the causes of OCD. However, first-line therapies include cognitive–behavioral therapy but only 40% of the patients respond to this first-line therapy. Research for a new treatment is mandatory. This review focuses on the potential effects of lithium, as a potential therapeutic strategy, on OCD and some of the presumed mechanisms by which lithium provides its benefit properties. Lithium medication downregulates GSK-3β, the main inhibitor of the WNT/β-catenin pathway. The activation of the WNT/β-catenin could be associated with the control of oxidative stress, inflammation, and glutamatergic pathway. Future prospective clinical trials could focus on lithium and its different and multiple interactions in OCD.


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