415. Comparison of Biological and Environmental Indicies in Elemental Mercury Exposure

1999 ◽  
Author(s):  
S. Casteel ◽  
R. Rush
PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 935-938
Author(s):  
Paul J. Hudson ◽  
Richard L. Vogt ◽  
Jack Brondum ◽  
Linden Witherell ◽  
Gary Myers ◽  
...  

Because evidence of mercury exposure was found among workers of a mercury thermometer-manufacturing plant in March 1984, the Vermont Department of Health studied the workers' children for both exposure to mercury and evidence of mercury toxicity. The median urine mercury level of 23 workers' children was 25 µg/L. This was significantly higher than the level (5 µg/L) among 39 children randomly selected from nonworkers' households in the same community (P < .001). Mercury-in-air levels measured in workers' homes were higher than those measured in control homes. A significant correlation was found between the urine mercury levels of the workers' children and the urine mercury levels of their working parents. No child had frank mercury toxicity. No evidence of neurologic toxicity among exposed children was discovered by a pediatric neurologist who examined these and unexposed children without knowledge of their exposure status. This is the first report demonstrating mercury exposure in children of mercury workers. Although toxic effects of mercury were not demonstrated at these levels of exposure, children of mercury workers are at risk for mercury exposure and potential mercury toxicity.


2008 ◽  
Vol 107 (1) ◽  
pp. 115-123 ◽  
Author(s):  
Alfred Bogomir Kobal ◽  
Marija Prezelj ◽  
Milena Horvat ◽  
Mladen Krsnik ◽  
Darija Gibicar ◽  
...  

2013 ◽  
Vol 9 (3) ◽  
pp. 270-273 ◽  
Author(s):  
Maryann Mazer-Amirshahi ◽  
Margit L. Bleecker ◽  
Fermin Barrueto

2014 ◽  
Vol 229 ◽  
pp. S229
Author(s):  
Zeliha Kayaalti ◽  
Dilek Kaya Akyuzlu ◽  
Esma Soylemez ◽  
Engin Tutkun ◽  
Fezile Özdemir ◽  
...  

PEDIATRICS ◽  
1988 ◽  
Vol 81 (5) ◽  
pp. 743-744
Author(s):  
LOY T. SWINEHART

To the Editor.— In the article by Hudson et al1 concerning mercury exposure of children of thermometor plant workers, they stated that "this is the first report demonstrating mercury exposure in children of mercury workers." On Sept 28, 1954, a case report of primary mercury poisoning in an infant was presented at a meeting of the North Pacific Pediatric Society, Victoria, British Columbia, Canada. Unfortunately, the case was never submitted for publication. The patient, a 20-month-old male infant, was referred because of fever, irritability, tremor, and refusal to walk.


1998 ◽  
Vol 14 (1) ◽  
pp. 123-134 ◽  
Author(s):  
Hellen Gelband

AbstractDental amalgam—a mixture of elemental mercury and a silver-dominated metal alloy—has been the most widely used dental filling material for well over a century. Alternative materials exist but are not well suited for some important applications, and all are more expensive than amalgam. The toxic effects of occupational mercury exposure have long been known, but it was not until about 1980 that serious consideration was given to the possibility that mercury vapor escaping from amalgam fillings might be affecting health, specifically producing subtle effects on the central nervous system. Such effects have been reported among dentists and other dental personnel, whose exposures are well below industrial levels but above those from fillings alone. No large studies have been completed that examine the effects of mercury exposure from dental amalgam fillings. In the face of inadequate evidence on the possible risks of dental amalgam, countries have reacted disparately. Sweden is phasing out amalgam entirely, possibly by the end of 1997. Germany has produced guidelines for limiting its use, other countries have signaled their intention to reduce it, and others—the United States and Canada—have studied the matter but taken no action. Policy differences within Europe have made dental amalgam a test case for the European Community's new medical device regulations. Relatively little epidemiologic research has been initiated to try to answer the question of dental amalgam's possible health effects. An international effort to define and carry out a research agenda to guide public policy is called for.


2006 ◽  
Vol 114 (2) ◽  
pp. 290-296 ◽  
Author(s):  
Darja Kobal Grum ◽  
Alfred B. Kobal ◽  
Niko Arnerič ◽  
Milena Horvat ◽  
Bernard Ženko ◽  
...  

Folia Medica ◽  
2021 ◽  
Vol 63 (5) ◽  
pp. 704-709
Author(s):  
Tahir Dalkiran ◽  
Kursat Bora Carman ◽  
Velid Unsal ◽  
Ergul Belge Kurutas ◽  
Yasar Kandur ◽  
...  

Objective:&nbsp;Very few studies have evaluated the association between mercury exposure and oxidative stress in humans, particularly in children. This is the first report where we aimed to determine the oxidative stress status of children who were accidently exposed to elemental mercury. Methods: In the present study, the study group was composed of 86 randomly selected children poisoned by mercury; the control group was composed of 78 children who had no history of mercury exposure. At admission, blood samples were collected. Blood superoxide dismutase activity, catalase enzyme activity, and glutathione peroxidase activity were measured by Fridovich, Beutler, and Lawrence Burk methods respectively, and the results were given as U/g Hb . Malondialdehyde level was measured by Ohkawa methods , and the results were given as mmol/ml. Results:&nbsp;Catalase levels were significantly lower in the patient group compared to the control group (1.28&plusmn;0.62 vs 3.90 &plusmn; 0.86 U/g Hb, p<0.01). In exposed children, SOD levels were significantly higher than the controls (5936 &plusmn; 810 vs 2226 &plusmn; 464 U/g Hb, p<0,05), while the GPx activity was significantly lower (13.01 &plusmn; 3.21&nbsp; vs 34.97 &plusmn; 7.32 U/g Hb, p<0.01). The MDA levels of the mercury group were significantly higher than the MDA levels of the control group (2.85&plusmn;0.84&nbsp; vs 2.05&plusmn;0.79 mmol/ml, p<0.05) . Conclusion: The results of the present study showed that acute mercury poisoning causes alteration of oxidative stress status in children exposed to elemental mercury.


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