scholarly journals Paraspinal Extraosseous Ewing's Sarcoma With Disseminated Metastases Masquerading As Pott's Spine

2013 ◽  
Vol 12 (3) ◽  
pp. 334-338
Author(s):  
Ansari Sajid ◽  
Ahmad Kaleem ◽  
Amanullah Md. Farid ◽  
Dhungel Kanchan ◽  
Gupta Mukesh Kumar ◽  
...  

A 16 years old girl presented with low back pain, fever and weakness in both lower limbs for 3 months. Plain radiograph shows lytic lesion in first sacral vertebra and multiple lung nodules. In suspicion of tuberculosis, antitubercular drugs were advised. But magnetic resonance imaging revealed right paraspinal soft tissue mass with multiple lesions in several vertebrae causing spinal canal compression alongwith lesions in iliac bones, sacrum, lung parenchyma and scalp tissue. Fine needle aspiration cytology and biopsy revealed Ewing’s sarcoma. Patient was referred to higher centre for chemotherapy/radiotherapy. Herein we report this rare case of extraosseous Ewing’s sarcoma with disseminated metastases masquerading as Pott’s spine. Bangladesh Journal of Medical Science Vol. 12 No. 03 July ’13 Page 334-338 DOI: http://dx.doi.org/10.3329/bjms.v12i3.15447

2014 ◽  
Vol 13 (2) ◽  
pp. 158-162
Author(s):  
Sanjay Sengupta ◽  
Rajib Kumar Mondal ◽  
Kingshuk Bose ◽  
Rudranarayan Ray ◽  
Sritanu Jana ◽  
...  

Background: Ovarian lesions are quite common among females of all age groups. Ovarian cancers account for 6% of female malignancy. Ultrasonography (USG) can help in proper identification and categorization of these lesions. Fine Needle Aspiration Cytology (FNAC) under USG guidance can be an effective modality for early diagnosis of ovarian masses. Aims And Objectives: To evaluate the role of USG guided FNAC over ovarian space occupying lesions (SOLs) for proper categorization into non-neoplastic, benign & malignant variants and to identify possible underlying causes of cytological misdiagnosis, if any, in comparison to histopathological diagnosis. Materials and Methods: FNAC under USG guidance were performed over one hundred and sixteen cases with radiologically proved ovarian SOLs during a period of five years. Aspirated materials were interpreted as non- neoplastic, benign or malignant lesions. Histopathological study was possible in 47 of these cases. Results: Out of 116 aspirations, non-neoplastic, benign and malignant diagnosis were given in 51, 42 & 23 cases, respectively. During histopathological correlation 41 out of 47 cases (87.2%) show exact cytohistological parity. Rest six cases with cytological misdiagnosis were discussed in detail. Conclusion: USG guided FNAC can effectively diagnose ovarian lesions in more than 87% cases. Scrutiny about failed diagnosis will help to improve accuracy in future. DOI: http://dx.doi.org/10.3329/bjms.v13i2.14520 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.158-162


Author(s):  
Lekshmi S.L. ◽  
Sudheesh S Nair ◽  
Sajitha I.S. ◽  
Soumya Ramankutty ◽  
Narayanan M.K. ◽  
...  

The present study was carried out to assess the pulmonary metastatic lesions in cases of canine superficial and mammary neoplasms presented to the University Veterinary Hospitals, Mannuthy and Kokkalai, Kerala Veterinary and Animal Sciences University during a twelve month period from February 2019 to February 2020. Twenty-four cases of neoplasms in dogs consisting of 12 cases of superficial neoplasms and 12 cases of mammary neoplasms were subjected to fine needle aspiration cytology (FNAC) for the confirmation of malignancy of neoplasm and three view thoracic radiographs were taken to assess the pulmonary metastatic pattern. The results were correlated with the malignancy detected in histopathological analysis after excisional biopsy. The most commonly observed pulmonary metastatic lesions were pulmonary nodules followed by pulmonary micronodules, miliary nodules, and pulmonary mass. These lesions were more evident in malignant mammary neoplasms especially in tubulopapillary carcinoma, ductal carcinoma, and medullary mammary carcinoma with spatial arrangements more in the perihilar region followed by caudodorsal, midventral, and cranioventral area of lung parenchyma. In case of superficial neoplasms miliary patterns and pulmonary microndules were mostly detected as pulmonary metastatic pattern in soft tissue sarcoma, round cell tumour, and malignant fibrohistiocytoma.


2016 ◽  
Vol 4 (2) ◽  
pp. 67-70
Author(s):  
Md Hasanuzzaman ◽  
Md Johirul Islam ◽  
AZM Mostaque Hossain ◽  
Mohammad Zillur Rahman ◽  
Md Ashraf Ul Haque ◽  
...  

Background: Tuberculous Mastitis (TM) is a rare form of tuberculosis, even in countries where the burden of tuberculosis is high. It may mimic other systemic illness, even carcinoma breast, a condition with which it may coexist.Objective: To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and method: This observational study was carried out in the department of Surgical Oncology of National Institute of Cancer Research & Hospital (NICRH), Dhaka, Bangladesh from January 2010 to December 2015. During the study period only five cases of TM were identified and all were included in the analysis purposively.Results: Mean(±SD) age of the patients was 27.2(±16.22) years. AFB in pus was found in one patient. Fine Needle Aspiration Cytology (FNAC) was done in four AFB negative patients and granulomatous lesions were found in each case. Histopathological examinations of two resected breast lumps also showed granulomatous lesions consistent with tuberculosis. Breast ultrasound showed multilocular abscess with ill-defined lump in two cases, solitary lump in two patients and cystic lesion in one patient. Axillary lymphadenopathy was found in one patient with solitary lump. Repeated image guided aspiration of the abscess was performed in 3 cases. Two patients underwent lumpectomy operation. All five patients were given anti-TB chemotherapy for 6 months. All of them recovered fully after completion of Category I treatment.Conclusion: Though it is a great mimicker with proper evaluation the disease is curable with antitubercular drugs, and in some cases surgery is required.Delta Med Col J. Jul 2016 4(2): 67-70


2014 ◽  
Vol 6 (01) ◽  
pp. 040-042
Author(s):  
Anita Bodh ◽  
Neelam Sharma ◽  
Lalita Negi ◽  
Suman S Chandel

ABSTRACTThyroid tuberculosis is a rare disease even in countries where tuberculosis is endemic. Clinically tuberculosis is not often suspected in cases of thyroid nodule or swelling. We report a case of 11 years female child who presented with a thyroid swelling. Fine-needle aspiration cytology revealed caseating epithelioid granulomas and acid fast bacilli. Patient improved with antitubercular drugs. Tuberculosis may be considered as differential diagnosis of thyroid swelling.


2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Madhan Jeyaraman ◽  
Sathish Muthu ◽  
Manoj Prabhakar ◽  
Naveen Jeyaraman ◽  
Garima Agarwal ◽  
...  

Introduction: Osseous angiosarcoma is a very rare tumor of bone with aggressive behavior, propensity for recurrences, and distant metastasis. The etiology of osseous angiosarcoma is uncertain; however, specific risk factors have been recognized. The diagnosis of angiosarcoma of bone demands multimodality imaging in conjunction with histopathological and vascular marker evaluation to aptly differentiate them from other vascular tumors. Treatment of osseous angiosarcoma remains controversial. Case Report: A 53-year-old male presented with pain and swelling of the right upper 1/3rd of the arm following heaviness while lifting weight for 3 months. He had a history of significant weight loss and appetite with no history of inciting trauma or irradiation in the past. On examination, a diffuse swelling was noted in the right shoulder and right scapular aspect with varied consistency and ill-defined borders and margins. The skin over the swelling was stretched and shiny with dilated engorged veins over it. The plain radiograph of the right shoulder with humerus revealed a large expansile lytic soft-tissue mass in the right proximal humerus with a wide zone of transition without sclerotic margins. Magnetic resonance imaging showed T1 hypointense, T2/PDFS hyperintense large well-defined expansile lytic lesion with multi-loculated cysts, and multiple blood-fluid levels involving right proximal humerus. The patient underwent an incisional biopsy which exhibited angiosarcoma of the humerus. The patient was treated with six cycles of chemotherapy with a mesna, doxorubicin, ifosfamide, and dacarbazine regimen. The patient was still under follow-up. Conclusion: Being a rare clinical entity, controversy exists in angiosarcoma of humerus regarding its etiology and recommended management protocols. Histopathology and immunohistochemistry remain the gold standard in differentiating osseous angiosarcoma from other osseous vascular tumors. The treatment protocol has to be standardized to


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Massood Hosseinzadeh ◽  
Navid Omidifar ◽  
Perikala Vijayananda Kumar ◽  
Alireza Rasekhi

Background. Extramedullary hematopoiesis is most often seen in reticuloendothelial organs specially spleen, liver, or lymph nodes, and it is rarely seen in lung parenchyma. Almost all reported cases of pulmonary extramedullary hematopoiesis occurred following myeloproliferative disorders specially myelofibrosis. Other less common underlying causes are thalassemia syndromes and other hemoglobinopathies. There was not any reported case of pulmonary extramedullary hematopoiesis in asthmatic patients in the medical literature.Case. Here we reported a 65-year-old lady who was a known case of bronchial asthma with recent developed right lower lobe lung mass. Chest X-ray and CT studies showed an infiltrating mass resembling malignancy. Fine needle aspiration cytology of mass revealed pulmonary extramedullary hematopoiesis. The patient followed for 10 months with serial physical examination and laboratory evaluations which were unremarkable.Conclusion.Extramedullary hematopoiesis of lung parenchyma can be mistaken for lung cancer radiologically. Although previous reported cases occurred with myelofibrosis or hemoglobinopathies, we are reporting the first case of asthma-associated extramedullary hematopoiesis.


2017 ◽  
Vol 1 (3) ◽  
pp. 31-36
Author(s):  
Rushin P. Patel ◽  
Shakti Goel ◽  
Pankaj R. Patel

Aneurysmal Bone Cyst (ABCs) is a cystic expansile lesion which is usually found in solitary locations in the metaphysis of long bones. The most common locations of ABC are long bones of lower limbs. There is little knowledge about the presence of this tumor in Clavicle. Here we present a case of a six year old male child who presented with complaint of swelling in left shoulder for four months. There was a dilemma in the diagnosis of the swelling due to its unusual presentation and appearance. The Fine Needle Aspiration Cytology was also inconclusive. The diagnosis of ABC was made only by excision biopsy. The Clavicle regenerated to nearly normal anatomy at 15 weeks follow up period. The patient is asymptomatic now and is able to perform all daily activities without any restrictions. The uniqueness of this case lies in the fact that this is the first case where ABC has been reported in Clavicular region in young Asian male of less than 10 years age. Keywords: ABC, Bone tumor, Expansile lesion.


2017 ◽  
Vol 16 (2) ◽  
pp. 274-280
Author(s):  
Shilpa Jalan ◽  
Sanjay Sengupta ◽  
Rudranarayan Ray ◽  
Rajib Mondal ◽  
Jyoti Phukan ◽  
...  

Aims & Objectives: To assess the relative usefulness of ultrasound (USG) guided fine needle aspiration cytology (FNAC) in diagnosis of thyroid lesions over conventional FNAC (C-FNAC) & to evaluate the possible causes of pitfalls of cytological diagnosis.Materials & Methods: The study included 84 patients with thyroid swellings. Among them 48 patients underwent only conventional FNAC & 36 underwent both conventional & USG guided FNAC (USGFNAC). Histology was available in 40 cases- 18 from C-FNAC patients & 22 from combined conventional & guided FNAC patients. Cyto-histological correlation was done & diagnostic accuracy calculated.Results: Inadequacy rate was higher with C-FNAC (10.42%) than that of USG-FNAC(2.78%). Sensitivity, specificity & diagnostic accuracy was 71.43%, 90.91%, 83.33% respectively with C-FNAC & 100%, 92.31% , 95.45% respectively with USG-FNAC. False positive & false negative rates were – 5.56% & 11.11% for C-FNAC and 4.55% & zero percent with USG-FNAC.Conclusion: FNAC under USG guidance significantly increases the diagnostic accuracy in thyroid lesions than C-FNAC alone; thus reducing the turnaround time & cost in accurate management.Bangladesh Journal of Medical Science Vol.16(2) 2017 p.274-280


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