scholarly journals Kikuchi-Fujimoto Disease, a rare cause of cervical lymph adenopathy

2014 ◽  
Vol 13 (2) ◽  
pp. 212-214
Author(s):  
Md. Jahangir Hossain Bhuiyan ◽  
Latifa Akhter

Kikuchi-Fujimoto Disease (KFD) present with Dysphagia, fever and lymphadenopathy. A young adult Bangladeshi female presented with fever and cervical lymphadenopathy. Broad-spectrum antibiotic (3rd generation oral cephalosporin) were given but no improvement after one month. FNAC suggested non specific lymphadenitis. Later on, excision biopsy of cervical lymph node was done and histopathology suggested KFD. Oral prednisolone was given showing improvement and no relapse was en-counted Awareness of this disorder by clinicians and pathologists will help misdiagnosis and inappropriate treatment. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18305 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.212-214

2021 ◽  
Vol 3 (2) ◽  
pp. 55-57
Author(s):  
P B Benny ◽  
P K Thomas ◽  
Rishikesan Nair ◽  
M. Gowri

Lymphadenopathy is not uncommon in toxoplasmosis. Its rare in an immunocompetent patient. We present a case of toxoplasmosis in an asymptomatic lady with isolated cervical lymph node. The diagnosis was confirmed by excision biopsy of lymph node and serology


2019 ◽  
Vol 4 (2) ◽  
pp. 1-6
Author(s):  
Mohammed Ahmed ◽  
Cyrus Daneshvar ◽  
David Breen

Background: A variety of disease processes investigated by respiratory physicians can lead to cervical lymphadenopathy. Ultrasound (US) has revolutionised respiratory investigations, and neck ultrasound (NUS) is increasingly recognised as an additional important skill for respiratory physicians. Objectives: We aimed to assess the feasibility of NUS performed by respiratory physicians in the workup of patients with mediastinal lymphadenopathy. Methods: This is a single-centre retrospective cohort study. All patients that underwent US-guided cervical lymph node sampling were included. The diagnostic yield is reported, and specimen adequacy is compared for respiratory physicians and radiologists. Results: Over 5 years, 106 patients underwent NUS-guided lymph node sampling by respiratory physicians compared to 35 cases performed by radiologists. There was no significant difference in the adequacy of sampling between the two groups (respiratory physicians 91.5% [95% CI 84.5–96%] compared to 82.9% [95% CI 66.4–93.4%] for radiologists [p = 0.2]). In the respiratory physician group, a diagnosis was achieved based on lymph node sampling in 89 cases (84%). Neck lymph node sampling was the only procedure performed to obtain tissue in 48 cases (45.3%). Conclusion: NUS and sampling performed by respiratory physicians are feasible and associated with an adequacy rate comparable to that of radiologists. It can reduce the number of invasive procedures performed in a selected group of patients. Guidelines for training and competency assessment are required.


1970 ◽  
Vol 7 (1) ◽  
pp. 1-5 ◽  
Author(s):  
G Shakya ◽  
S Malla ◽  
KN Shakya ◽  
R Shrestha

Background: Fine Needle Aspiration Cytology (FNAC) is a reliable and least expensive method suitable for developing countries like Nepal for the investigation of lymphadenopathy. Knowledge about the pattern of lymphadenopathy is useful in pathological reporting as well as in many clinical settings with diagnostic dilemma. This is a baseline study to investigate the pattern of cervical lymphadenopathy by lymph node FNAC in Nepalese population. Methods: A retrospective study was conducted by critically analyzing the case reports on cervical lymph node FNAC from three years' records (July 2005 to June 2008) at the National Public Health Laboratory, Teku, Kathmandu. Review of all cytological reports were done according to standard guidelines and the diagnosis was classified and correlated with patients' age and ethnicity to explore the pattern and association. Results: Of 508 cervical lymph node FNAC cases, 50.4% was reactive non-specific, 22.4% was tubercular, 4.8 % malignant, 10% chronic granulomatous and the remaining was acute suppurative (12.4%). Highest incidence of malignancy was seen in the fifth decade (50%). Whereas, tubercular lymphadenopathy was found with increasing frequency through childhood (10.5%) and adolescence (21.7%) to young adulthood (30.4%), probably indicative of waning immunity of BCG vaccination. Ethnic groups comprising of Tamang, Sherpa and Bhote had the highest incidence of malignant as well as tubercular lymphadenopathy. Conclusion: The relationship of malignant and tubercular lymphadenopthy with age and ethnicity deserves further study. Efforts at preventing tubercular and early diagnosing malignant lymphadenopathy and reducing morbidity in general will find great usefulness in such associations. Key words: Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Pattern   DOI: 10.3126/jnhrc.v7i1.2267 Journal of Nepal Health Research Council Vol. 7, No. 1, 2009 April 1-5


2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S106-S106
Author(s):  
Branimir Gjurasin ◽  
Josip Begovac

Abstract Background Lymphogranuloma venereum (LGV) can present with genital ulcers, proctitis, or femoral/inguinal lymphadenopathy with or without constitutional symptoms. There have been reports on the infection characterized by supraclavicular or cervical lymphadenopathy, although there is no published data on the detection of Chlamydia trachomatis (CT) in the affected lymph node. Methods We report a patient with pharyngitis, proctitis and cervical lymphadenitis, in whom LGV specific DNA was detected by polimerase chain reaction (PCR) in both the rectal swab and cervical lymph node fine needle aspirate. Results A 48-year-old Croatian HIV-positive male patient attended our outpatient HIV clinic complaining of a 10-day perianal pain, bloody rectal discharge with normal stool consistency and painful and enlarged cervical lymph node. On the first day he had fever, which subsided on the following day. Clinical examination demonstrated exudate on the right tonsil, painful, and enlarged right cervical lymph node (5 × 2 cm, Figure 1), perianal pain on palpation and rectal purulent discharge. During the preceding 10-year period, the patient was taking his antiretroviral therapy regularly and had an undetectable HIV RNA by PCR. We started treatment with ceftriaxone and doxycycline. The fine needle aspirate of the affected lymph node showed a pyogranulomatous inflammation. Indirect immunofluorescence assay on CT antibodies detected positive titers in IgG (>512) and IgA (256) classes. LGV-specific DNA was detected in both the rectal swab and the cervical lymph node fine needle aspirate. Ceftriaxone was discontinued after 5 days and doxycycline therapy was continued for a total of 6 weeks because of the persistence of the cervical lymphadenopathy. The patient came to a full recovery. Conclusion We found six published case reports on LGV with associated cervical lymphadenopathy in which the infection with CT was established by serologic testing and/or by nucleic acid amplification tests of the pharyngeal and/or rectal swabs. Some of the mentioned reports demonstrated granulomatous inflammation present in the affected cervical lymph node, as was evidenced in our patient. To our knowledge, this is the first case report of a patient with CT infection in whom LGV-specific DNA was detected in the cervical lymph node. Disclosures All authors: No reported disclosures.


2002 ◽  
Vol 81 (11) ◽  
pp. 776-778 ◽  
Author(s):  
Scott H. Hardeman ◽  
Brian Collins ◽  
Val J. Lowe ◽  
Harvey Solomon ◽  
Brendan C. Stack

We describe a unique case of a cholangiocarcinoma that metastasized to a cervical lymph node—to our knowledge the only such case ever reported. The diagnosis was based on fine-needle aspiration cytology and confirmed by excision biopsy. This case illustrates the importance of keeping all possible options in mind when diagnosing head and neck masses.


Author(s):  
Abhinav Srivastava ◽  
Shivesh Kumar ◽  
Ranjan Agarwal

ABSTRACT Filariasis is endemic worldwide with the main focus in the tropical areas. Reported cases of filarial lymphadenopathy are caused by Wuchereria bancrofti, which is limited to the groin, the femoral triangle, and axilla, causing lymphedema of lower and upper limbs, and is usually diagnosed clinically and by the presence of microfilaria in peripheral blood smear. We are reporting an unusual case of cervical lymphadenitis, which on fine needle aspiration cytology (FNAC) showed microfilaria of a rare species, Brugia malayi. The purpose of this article is to make clinicians aware of this rare disease as one of the differential diagnoses of cervical lymphadenopathy in an endemic country like India. How to cite this article Srivastava A, Mohan C, Kumar S, Agarwal R. Brugia malayi in Cervical Lymph Node Aspirate: A Rare Case Report. Int J Adv Integ Med Sci 2016;1(2):79-80.


Author(s):  
Sarder M. Abu Horaira

Background: Cervical lymphadenopathy is a frequently encountered neck lesion in routine daily practice all over the globe. The etiology varies from a benign inflammatory process to a malignant condition. Fine needle aspiration cytology (FNAC) is now a days the initial investigation in most of the cases of cervical lymph node enlargement. The aim of this work was to evaluate the efficacy and diagnostic accuracy of fine needle aspiration cytology of cervical lymph nodes with an emphasis on discordant cases between the cytology and the histopathology.Methods: The present study was a retrospective one, conducted at the department of pathology, Rajshahi medical college and hospital located in west-northern region of Bangladesh over a period of one year (January 2019 to December 2019). FNAC assessed and histopathologically correlated 122 documented cases were included in the study.Results: The cytological diagnoses were detected to be benign in 107 cases (87.70%) and malignant in 15 cases (12.30%). Reactive lymphadenitis (67.20%) was the most common benign lesion followed by granulomatous lymphadenitis (16.40%). The overall diagnostic sensitivity, specificity, positive predictive value and negative predictive value of cytological diagnosis of cervical lymph node were 97.16%, 75%, 96.26% and 80%, respectively. The overall diagnostic accuracy was 94.26% while the overall discordance rate was 5.73%.Conclusions: FNAC is the preliminary investigation of choice in the diagnostic approach to most of the cases of cervical lymphadenopathy and it has good diagnostic sensitivity, specificity and accuracy.


2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
R. D. Jayasinghe ◽  
W. A. M. U. L. Abeysinghe ◽  
P. I. Jayasekara ◽  
Y. S. Mohomed ◽  
B. S. M. S. Siriwardena

Phaeohyphomycosis is a fungal infection caused by Dermatiacae group of fungi, by Cladosporium spp. The term phaeohyphomycosis was introduced by Ajello et al. in 1974 to designate infections by brown pigmented filamentous fungi. Cladosporium oxysporum is a very rare etiological agent in humans. Phaeohyphomycosis of the cervical lymph node in an immunocompetent individual is a very rare clinical entity. To the best of our knowledge we report the first case of phaeohyphomycosis caused by Cladosporium oxysporum in the absence of other systemic manifestations in a 16-year-old male.


2020 ◽  
Vol 8 ◽  
pp. 232470962094931 ◽  
Author(s):  
Ameesh Dev ◽  
Dawn Janysek ◽  
James Gnecco ◽  
Kamyar Haghayeghi

A 35-year-old male presented to our university hospital with night sweats, fevers, ulcerated skin lesions to the lower mouth and posterior neck, shortness of breath, and an enlarging cervical lymph node. The patient was evaluated 2 months prior for respiratory symptoms, cervical lymphadenopathy, and skin lesions resulting in a diagnosis of primary pulmonary coccidioidomycosis and was treated with a 4-week course of fluconazole. On presentation to our hospital, initial laboratory test results revealed leukocytosis, increased liver enzymes, elevated inflammatory markers, and hypercalcemia. Computed tomography scan of the chest revealed lung nodules in a miliary pattern and prominent mediastinal lymphadenopathy. Magnetic resonance imaging revealed multiple vertebral and iliac bone lesions, as well as bilateral psoas muscle lesions. Serum ELISA (enzyme linked immunosorbent assay) detected elevated serological markers against coccidioides, and sputum culture revealed coccidioides arthroconidia, confirming the presence of an acute coccidioides infection. Biopsy of the right iliac crest and cervical lymph node revealed spherules resembling coccidioides, escalating the diagnosis to disseminated coccidioidomycosis. The patient’s hospital course was complicated by septic shock, acute respiratory distress syndrome requiring several days of mechanical ventilation, and acute kidney injury. He was ultimately treated with several weeks of voriconazole and liposomal amphotericin-B. He made a full recovery and was discharged on an extended course of oral voriconazole. Our case highlights the importance of recognition and appropriate treatment duration of disseminated coccidioidomycosis at initial presentation. Failure to do so may lead to increased morbidity and mortality.


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