scholarly journals Study of Antihypertensive effects of Ocimum sanctum

2016 ◽  
Vol 15 (3) ◽  
pp. 357-361
Author(s):  
Md Borhanuddin
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Effect ◽  
Methanol Extract ◽  
Soluble Fraction ◽  
Medical Science ◽  
Water Extract ◽  
Water Soluble ◽  
Ocimum Sanctum ◽  
Albino Rats ◽  
Water Soluble Fraction

Background: Ocimum sanctum is a well reputed medicinal herb being used in the treatment of various ailments in this Indo Pak Subcontinents since ancient time.Methods: In this study the Antihypertensive effects of water extract of Ocimum sanctum and Water soluble fraction of methanol extract of Ocimum sanctum were tried for its antihypertensive effects on albino rats. Extracts were administered via vein and BP was recorded in the carotid artery by direct invasive method.Result: Normal blood pressure was 81/71 mm of Hg (mean blood pressure was 75 mm of Hg. Water extract of Ocimum sanctum has got significant antihypertensive effect (19-30 %). Water soluble fraction of methanol extract of Ocimum sanctum has also got significant antihypertensive effect (15-27 %).Bangladesh Journal of Medical Science Vol.15(3) 2016 p.357-361

scholarly journals Nephrotoxicological Effect of Water Soluble Fraction of Bonny Light Crude Oil in Wistar Albino Rats

2019 ◽  
pp. 1-9
Author(s):  
Abraham, Chiedozie Nicholas ◽  
J. Udom, Godwin ◽  
C. Patrick-Iwuanyanwu, Kingsley
Keyword(s):  
Crude Oil ◽  
Soluble Fraction ◽  
Water Soluble ◽  
Albino Rats ◽  
Renal Tubules ◽  
Water Soluble Fraction ◽  
Light Crude Oil ◽  
Range Finding ◽  
Effect Of Water ◽  
Wistar Albino Rats

This study evaluated the Nephrotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO). After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BLCO for 30 and 60days. Data from the study showed that Urea concentration increased significantly (p≤0.05) with increasing dose of BLCO ranging from 14.71 mg/dl in the control to 35.28 mg/dl in the 100% group after 30days and 14.28 mg/dl in the control to 41.08mg/dl in the 100% group after 60days, Creatinine concentration increased significantly (p≤0.05) from 0.22 mg/dl in the control to 0.82mg/dl in the 100% group after 60 days administration while electrolyte (Na, K, Cl) concentration increased significantly (p≤0.05) with increasing dose of BLCO after 60days administration. Histopathological examination of the kidney was characterized by partial partitioning of the glomerular tufts, obliteration of the Bowman’s capsule and distortion of the renal tubules. The findings in this research suggest that WSF of BLCO induced nephrotoxicity.

scholarly journals Hematotoxic Effect of Water Soluble Fraction of Bonny Light Crude Oil in Wistar Albino Rats

2020 ◽  
pp. 1-5
Author(s):  
Abraham, Chiedozie Nicholas ◽  
Godwin J. Udom ◽  
Kingsley C. Patrick-Iwuanyanwu
Keyword(s):  
Crude Oil ◽  
Soluble Fraction ◽  
Water Soluble ◽  
Control Group ◽  
Albino Rats ◽  
Water Soluble Fraction ◽  
Light Crude Oil ◽  
Range Finding ◽  
Effect Of Water ◽  
Wistar Albino Rats

This study evaluated the Hematotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO) in Wistar Albino rats. After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BLCO for 30 and 60days. Data from the study showed that there was a significant decrease (p≤0.05) in PCV values (30.2% in the control group to 17.2% in the 100% group), Hb levels decreased significantly from 9.25 g/dl in the control group to 5.27 g/dl in the 100% group. WBC count decreased significantly from 2932 mm3 in the control group to 136 mm3 in the 100% group and finally RBC count decreased significantly from 241.8E4 mm3 to 567 mm3 with increasing concentrations in the treatment groups after 60days administration. These results suggest that the oral consumption of the WSF of BLCO led to an onset of anaemia which indicates the presence of less than normal concentrations of PCV, Hb and RBC.

Impact of Rice Flour Cold-Water-Soluble Fraction Removal on Gelatinization and Pasting Properties

2014 ◽  
Vol 91 (5) ◽  
pp. 473-481 ◽  
Author(s):  
Guiai Jiao ◽  
Xiangjin Wei ◽  
Gaoneng Shao ◽  
Lihong Xie ◽  
Zhonghua Sheng ◽  
...  
Keyword(s):  
Cold Water ◽  
Soluble Fraction ◽  
Rice Flour ◽  
Pasting Properties ◽  
Water Soluble ◽  
Water Soluble Fraction

FRACTIONATION OF LIVETIN AND THE MOLECULAR WEIGHTS OF THE α- AND β-COMPONENTS

1957 ◽  
Vol 35 (4) ◽  
pp. 241-250 ◽  
Author(s):  
W. G. Martin ◽  
J. E. Vandegaer ◽  
W. H. Cook
Keyword(s):  
Light Scattering ◽  
Soluble Protein ◽  
Soluble Fraction ◽  
Egg Yolk ◽  
Water Soluble ◽  
Water Soluble Fraction ◽  
Molecular Weights ◽  
Water Soluble Protein ◽  
Hen Egg Yolk ◽  
Hen Egg

Livetin, the major water-soluble protein of hen egg yolk, was found to contain three major components having mobilities of −6.3, −3.8, and −2.1 cm.2 sec.−1 volt−1 at pH 8, µ 0.1, and these have been designated α-, β-, and γ-livetin respectively. The α- and β-livetins were separated and purified electrophoretically after removal of γ-livetin by precipitation from 37% saturated ammonium sulphate or 20% isopropanol. The α-, β-, and mixed livetins resembled pseudoglobulins in solubility but γ-livetin was unstable and this loss of solubility has, so far, prevented its characterization. Molecular weights determined by light scattering, osmotic pressure, and Archibald sedimentation procedure yielded respectively: 8.7, 7.8, and 6.7 × 104 for α-livetin, and 4.8, 5.0, and4.5 × 104 for β-livetin. Under suitable conditions of sedimentation and electrophoresis, egg yolk has been shown to contain three components having the same behavior as the three livetins of the water-soluble fraction.

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