scholarly journals Clinical profile and management outcome of Parathyroid Adenoma - A 7 years retrospective study

2015 ◽  
Vol 20 (1) ◽  
pp. 27-34
Author(s):  
Md Arif Hossain Bhuyan ◽  
Abu Yusuf Fakir ◽  
Md Nurullah ◽  
Md Abdullah Hil Kafi ◽  
Sk Nurul Fattah Rumi ◽  
...  

The study aims to present the clinical profile and management outcomes of parathyroid adenoma patients in our institutions. This retrospective study included ten patients with parathyroid adenoma presented to Department of Otolaryngology and Head-Neck Surgery at Dhaka Medical College Hospital and Ibn Sina Medical College Hospital, Dhaka from January 2004 to January 2011.Out of 10 patients, 8 were female. Average age of presentation was 50 years. 6 patients were symptomatic and 4 were asymptomatic. In 8 patients, serum creatinine level was within normal limits and 2 patients had elevated serum creatinine level. All 10 patients had hypercalcaemia and increase parathormone level, from mild to severe. CT guided fine needle aspiration cytology diagnosed 2 cases preoperatively. 6 patients diagnosed with 99mTc Sestamibi scan and 3 patients diagnosed by single photon emission computed tomography (SPECTCT) dual isotope (I-123/99mTc-MIBI) substraction for imaging parathyroid adenoma. All the patients underwent parathyroidectomy except for 1 patient in whom hemithyroidectomy was done. Postoperative period was not without complications but has been managed with strong monitoring. Long term follow up was done up to 1 year with 100% cure rate. DOI: http://dx.doi.org/10.3329/bjo.v20i1.22014 Bangladesh J Otorhinolaryngol; April 2014; 20(1): 27-34

Author(s):  
Sanyal M ◽  
Khan A

Serum creatinine is a very common tool of renal assessment in diabetic nephropathy. Specially due to its availably and cost-effectiveness, serum creatinine has been a popular choice among the clinicians even in rural areas. Also, the staging of diabetic nephropathy is done on the basis of eGFR which is calculated mainly with serum creatinine level. Sometimes, clinicians , even overlook the other investigations ,such as urine routine examinations or ultra sonogram of kidney, when the serum creatinine level is within normal limit. This study aims at observation of existing correlation between serum creatinine and urine albumin in diabetic nephropathy patients. This cross sectional observational study has been conducted on 50 patients in a period of 6 months in the medicine department of Dhaka Medical College Hospital. 50 diabetic patients admitted to Dhaka Medical College Hospital were enrolled in this study after fulfilling inclusion and exclusion criteria. Among the total 50 patients, 34 patients were diagnosed on the basis of microalbuminuria and the rest had raised urinary total protein. No correlation was found between serum creatinine and urine albumin or urine total protein. Staging of the kidney disease was done according to eGFR (calculated by MDRD equation).  Only 41.37% of the patients with microalbuminuria, showed eGFR consistent with its staging while 31.5% of the patients with proteinuria showed respective expected eGFR. The rest of the patient’s eGFR was inconsistent with the staging. And the difference between the mean serum creatinine in two groups was insignificant. This study has shown that, the serum creatinine has no linear correlation with urinary albumin in diabetic nephropathy patients. So, commonly used serum creatinine based formula to calculate the eGFR can misinterpret the staging of the disease which can delay the appropriate treatment thereafter. Keywords: Diabetic Nephropathy, Proteinuria, Microalbuminuria, Serum Creatinine


2020 ◽  
pp. 80-82
Author(s):  
Shweta Shah ◽  
S.K. Suri ◽  
Ami Shah

Background: Most frequently performed gynaecological surgery is hysterectomy. The prevalence of hysterectomy varies within different regions. There are mainly two types of hysterectomies according to which part of uterus is removed. The main types of hysterectomy are total and subtotal or partial hysterectomy. The hysterectomy can be performed by three routes abdominal, laproscopic and vaginal hysterectomy. The main objective of our study is to know most common pathology and different age groups of the patients underwent hysterectomy. Materials and Methods: In this retrospective study was carried during period 6 months, at GCS medical college, hospital and research centre, Ahmedabad. Total 100 hysterectomy specimens were analyzed for histopathological lesions. We had taken the clinical and histopathological findings of these cases from the records of department of pathology, GCS medical college , hospital and research centre. Results: In our study of 100 cases, most common age group underwent hysterectomy was 40-49 years and least common age group was 20-29 years. Type of hysterectomy performed most commonly in this study was total abdominal hysterectomy with bilateral salpingoophorectomy. Most of lesions were seen in the myometrium 42 cases (42%), Endometrium 32 cases (32%), Cervix 16 cases (16%) and Ovary 10 cases (10%). Hysterectomy remains the widely used treatment modality.


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