scholarly journals Establishment of Reference Range for Serum Creatinine by IDMS and NIST SRM 967 Traceable Calibrator in Government Kilpauk Medical College Hospital Laboratory

Author(s):  
Sanyal M ◽  
Khan A

Serum creatinine is a very common tool of renal assessment in diabetic nephropathy. Specially due to its availably and cost-effectiveness, serum creatinine has been a popular choice among the clinicians even in rural areas. Also, the staging of diabetic nephropathy is done on the basis of eGFR which is calculated mainly with serum creatinine level. Sometimes, clinicians , even overlook the other investigations ,such as urine routine examinations or ultra sonogram of kidney, when the serum creatinine level is within normal limit. This study aims at observation of existing correlation between serum creatinine and urine albumin in diabetic nephropathy patients. This cross sectional observational study has been conducted on 50 patients in a period of 6 months in the medicine department of Dhaka Medical College Hospital. 50 diabetic patients admitted to Dhaka Medical College Hospital were enrolled in this study after fulfilling inclusion and exclusion criteria. Among the total 50 patients, 34 patients were diagnosed on the basis of microalbuminuria and the rest had raised urinary total protein. No correlation was found between serum creatinine and urine albumin or urine total protein. Staging of the kidney disease was done according to eGFR (calculated by MDRD equation).  Only 41.37% of the patients with microalbuminuria, showed eGFR consistent with its staging while 31.5% of the patients with proteinuria showed respective expected eGFR. The rest of the patient’s eGFR was inconsistent with the staging. And the difference between the mean serum creatinine in two groups was insignificant. This study has shown that, the serum creatinine has no linear correlation with urinary albumin in diabetic nephropathy patients. So, commonly used serum creatinine based formula to calculate the eGFR can misinterpret the staging of the disease which can delay the appropriate treatment thereafter. Keywords: Diabetic Nephropathy, Proteinuria, Microalbuminuria, Serum Creatinine


2015 ◽  
Vol 20 (1) ◽  
pp. 27-34
Author(s):  
Md Arif Hossain Bhuyan ◽  
Abu Yusuf Fakir ◽  
Md Nurullah ◽  
Md Abdullah Hil Kafi ◽  
Sk Nurul Fattah Rumi ◽  
...  

The study aims to present the clinical profile and management outcomes of parathyroid adenoma patients in our institutions. This retrospective study included ten patients with parathyroid adenoma presented to Department of Otolaryngology and Head-Neck Surgery at Dhaka Medical College Hospital and Ibn Sina Medical College Hospital, Dhaka from January 2004 to January 2011.Out of 10 patients, 8 were female. Average age of presentation was 50 years. 6 patients were symptomatic and 4 were asymptomatic. In 8 patients, serum creatinine level was within normal limits and 2 patients had elevated serum creatinine level. All 10 patients had hypercalcaemia and increase parathormone level, from mild to severe. CT guided fine needle aspiration cytology diagnosed 2 cases preoperatively. 6 patients diagnosed with 99mTc Sestamibi scan and 3 patients diagnosed by single photon emission computed tomography (SPECTCT) dual isotope (I-123/99mTc-MIBI) substraction for imaging parathyroid adenoma. All the patients underwent parathyroidectomy except for 1 patient in whom hemithyroidectomy was done. Postoperative period was not without complications but has been managed with strong monitoring. Long term follow up was done up to 1 year with 100% cure rate. DOI: http://dx.doi.org/10.3329/bjo.v20i1.22014 Bangladesh J Otorhinolaryngol; April 2014; 20(1): 27-34


2020 ◽  
Vol 22 (2) ◽  
pp. 110-117
Author(s):  
Md Mahmudul Islam ◽  
Khondkar AK Azad ◽  
Md Aminul Islam ◽  
Rivu Raj Chakraborty

Background: Chest trauma is responsible for 50% of deaths due to trauma. This kind of death usually occurs immediately after the trauma has occurred. Various therapeutic options have been reported for management of chest injuries like clinical observation, thoracocentesis, tube thoracostomy and open thoracotomy. Objective: To observe the pattern and outcome of management in chest trauma Methods: This is an observational study carried out in Casualty department of Chittagong Medical College Hospital (CMCH), Chittagong, between April 2015 to March 2016. Our study was included all patients, both sexes, following chest injury at Casualty units of Chittagong Medical College Hospital. All the data were recorded through the preformed data collection sheet and analyzed. Result: The mean age was found 37.7±18.1 years with range from 12 to 80 years. Male female ratio was 11.8:1. The mean time elapsed after trauma was found 6.1±3.1 hours with range from 1 to 72 hours. Almost one third (35.7%) patients was affecting road traffic accident followed by 42(27.3%) assault, 35(22.7%) stab injury, 15(9.7%) fall and 7(4.5%) gun shot . More than three fourth (80.5%) patients were managed by tube thoracostomy followed by 28(18.2%) observation and 2(1.3%) ventilatory support. No thoracotomy was done in emergency department. 42(27.2%) patients was found open pneumothorax followed by 41(26.6%) rib fracture, 31(20.1%) haemopneumothorax, 14(9%) simple pneumothorax, 12(7.8%) haemothorax, 6(3.9%) chest wall injury, 5(3.2%) tension pneumothorax, and 3(1.9%) flail chest. About the side of tube 60(39.0%) patients were given tube on left side followed by 57(37.0%) patients on right side, 9(5.8%) patients on both (left & right) side and 28(18.2%) patients needed no tube. Regarding the complications, 13(30%) patients had persistent haemothorax followed by 12(29%)tubes were placed outside triangle of safety, 6(13.9%) tubes were kinked, 6(13.9%) patients developed port side infection, 2(4.5%)tube was placed too shallow, 2(4.5%) patients developed empyema thoracis and 2(4.5%) patients developed bronchopleural fistula. The mean ICT removal information was found 8.8±3.6 days with range from 4 to 18 days. Reinsertion of ICT was done in 6(4.7%) patients. More than two third (68.2%) patients were recovered well, 43(27.9%) patients developed complication and 6(3.9%)patients died. More than two third (66.9%) patients had length of hospital stay 11-20 days. Conclusion: Most of the patients were in 3rd decade and male predominant. Road traffic accident and tube thoracostomy were more common. Open pneumothorax, rib fracture and haemopneumothorax were commonest injuries. Nearly one third of the patients had developed complications. Re-insertion of ICT needed almost five percent and death almost four percent. Journal of Surgical Sciences (2018) Vol. 22 (2) : 110-117


1970 ◽  
Vol 19 (2) ◽  
pp. 98-101 ◽  
Author(s):  
R Khanom ◽  
DK Saha ◽  
K Begum ◽  
J Nur ◽  
S Tanira

Objective: This study aims to describe main perpetrator of violence area and prevention of violence against women. Study design: A cross sectional study was carried out in One-stop Crisis Centre (OCC) of Dhaka Medical College Hospital, Dhaka, Bangladesh during the period of June 2006 to May 2007. Methods: 284 victims reported in OCC during the study period were selected as cases for the study and quantitative information was collected from them using cross sectional for the present study. Results: Study shows that most of the violence is done by husband (46.48%) and prevalence is more in rural areas (80.98%) in comparison to urban area (19.02%). Physical assault is the most common type of violence (50.35%), followed by sexual assault (36.63%) and burn (13.02%) Housewives are tortured more (67%). Conclusion: Proper implementation of existing rules and community based interventions for raising awareness about the domestic violence against women are recommended. Key words: Violence against women; assault; human rights; one-stop crisis centre (OCC); Bangladesh. DOI: 10.3329/jdmc.v19i2.7077J Dhaka Med Coll. 2010; 19(2) : 98-101


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