scholarly journals A single pathological grading system for breast carcinoma should be adopted in Bangladesh

1970 ◽  
Vol 24 (2) ◽  
pp. 11-14
Author(s):  
Tuhin Sultana ◽  
Abdul Allam Chowdhury ◽  
Quddusur Rahman ◽  
AN Nashimuddin Ahmed ◽  
AJE Nahar Rahman
Keyword(s):  
Breast Carcinoma ◽  
Grading System

DOI: 10.3329/bjpath.v24i2.4112Bangladesh J Pathol 24(2): 11-14

Agreement between core needle biopsy and surgical excision product: the importance of the invasive breast carcinoma grading system

2021 ◽  
Author(s):  
Rodrigo Justi Nogueira ◽  
Thales Müller Silvério Alves ◽  
Mário Jefferson Quirino Louzada ◽  
Deolino João Camilo-Júnior ◽  
José Cândido Caldeira Xavier-Júnior
Keyword(s):  
Breast Carcinoma ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Invasive Breast Carcinoma ◽  
Grading System ◽  
Core Needle

A study of Transferrin expression in comparison with Modified Scarff-Bloom Richardson's grading system in Breast carcinoma

2016 ◽  
Vol 3 (1) ◽  
pp. 38
Author(s):  
Rajeswari Kathiah ◽  
K Meenakshisundaram ◽  
G Anushuya ◽  
V Rajalakshmi
Keyword(s):  
Breast Carcinoma ◽  
Grading System

Relevance of modified prognostic score for breast carcinoma on fine needle aspiration cytology in a resource-poor setting

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 21177-21177
Author(s):  
S. A. Malami ◽  
S. M. Sahabi
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Biological Behavior ◽  
Grading System ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Prognostic Group ◽  
Needle Aspiration Cytology

21177 Background: Breast cancer is the commonest malignancy in premenopausal Nigerian women in whom it is almost uniformly fatal probably due to lack of access to early diagnosis and treatment. To enhance the value of fine needle aspiration cytology, a rapid and comparatively new technique in our center, we sought to verify if it is also a cost-effective test to predict biological behavior in breast carcinoma. We developed a modified grading system to compare the cytologic features of the cases in our series with known prognostic factors (tumours size, histologic grade and axillary lymph node status) in subsequently excised tissues. Methods: Fine needle aspirates obtained in 42 patients diagnosed as ductal cell carcinoma not otherwise specified (NOS) at the UDUTH Hospital, Sokoto, Nigeria were investigated. The three cytologic features used were nuclear grade (score 1–3), cellular dyscohesion (score 1–3), and bare atypical nuclei (score 0, 1). A cytological score of 3 and below was considered a low score, and a score of 4–7 was considered a high score. We also categorized each patient according to the Nottingham Prognostic Index (NPI) into: good prognostic group (GPG), moderate prognostic group (MPG) and poor prognostic group (PPG). The cases in GPG and MPG were considered to belong to a more favourable category. Results of cytoprognostic scores were compared with the respective pathological information calculated by the NPI. Results: Eighteen of the 20 cases that had a cytologically high score were confirmed to be PPG while 2 correlated with MPG. Among the 22 cases that had cytologically low scores 14 cases were not correlated with favourable NPI index (belonged to PPG category) while the remaining 8 correlated well (MPG = 4 and GPG = 4). The overall accuracy for cytologic grading was 62% (26 out of 42 cases). Conclusion: Tumour typing on FNA material correlates with the NPI in the poor prognostic group. However, this modified cytoprognostic score seems to have doubtful promise as a prognostic factor in our group of patients with favourable NPI. The importance of each cytological feature used in this grading system will be determined by regression analysis in a larger sample size. No significant financial relationships to disclose.

scholarly journals Cytological grading of breast carcinoma on fine needle aspirates and its relation with histological grading

2015 ◽  
Vol 04 (01) ◽  
pp. 032-034 ◽  
Author(s):  
Jyoti Prakash Phukan ◽  
Anuradha Sinha ◽  
Jatindra Prasad Deka
Keyword(s):  
Breast Carcinoma ◽  
Neoadjuvant Chemotherapy ◽  
Needle Aspiration ◽  
Grading System ◽  
Low Grade ◽  
Histological Grading ◽  
Fine Needle ◽  
Primary Treatment Modality ◽  
Grade Ii ◽  
Grade Iii

Abstract Background: Grading of breast carcinoma on fine needle aspiration cytology (FNAC) is beneficial for selecting patients for neoadjuvant chemotherapy. Aims: To grade the breast carcinoma on FNAC using Robinson grading system and to assess the concordance of cytological grading (CG) with histological grading (HG) using Elston-Ellis modification of Scarff-Bloom-Richardson grading system. Materials and Methods: The study was conducted for 1-year, comprising of 50 female patients attending outpatient departments (OPD) as well as admitted in various surgical wards of a teaching hospital, diagnosed as breast carcinoma. FNAC smears were stained with May-Grunwald-Giemsa and Papanicolaou (Pap) stains and CG was done using Robinson system on Pap stained smears. The results were compared with HG system after resection of tumors. Results: Of 50 cases, 14 (28%) cases were graded as grade I, 24 (48%) grade II, and 12 (24%) grade III by CG, whereas 9 (18%), 28 (56%) and 13 (26%) cases were graded as grade I, II and III by HG. The result showed overall 72% concordance of CG with HG, with grade II and grade III showing highest degree of concordance (83.33%), which is comparable to previous studies. Kappa measurement showed a higher degree of agreement in high-grade tumors compared with low-grade tumors (0.73 in grade III, 0.53 in grade II and 0.39 in grade I). Conclusion: Cytological grading is comparable to HG in majority of cases. Because neoadjuvant chemotherapy is becoming increasingly popular as primary treatment modality of breast cancer, CG could be a useful parameter in selecting the mode of therapy and predicting tumor behavior.

Cell proliferation in breast carcinoma assessed by a PCNA grading system and its relation to other prognostic variables

1993 ◽  
Vol 2 (1) ◽  
pp. 59-63 ◽  
Author(s):  
P.G. Betta ◽  
G. Bottero ◽  
M. Pavesi ◽  
M. Pastormerlo ◽  
D. Bellingeri ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Breast Carcinoma ◽  
Grading System ◽  
Prognostic Variables

A single point cytological grading system for breast carcinoma

2019 ◽  
Vol 9 (3) ◽  
pp. 121-125
Author(s):  
Hemalatha J ◽  
◽  
Deepak Kumar B ◽  
Srinivasa Murthy V ◽  
Padmapriya Kasukurti ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Single Point ◽  
Grading System
Sign in / Sign up

Export Citation Format

Share Document