scholarly journals Efficacy of topical tacrolimus 0.1% in the treatment of vitiligo

2014 ◽  
Vol 3 (1) ◽  
pp. 4-7
Author(s):  
Afsana Nahid ◽  
Lubna Khondker ◽  
Md Shirajul Islam Khan ◽  
Samaresh Chandra Hazra

A clinical trial was carried out with thirty patients affected with vitiligo. Repigmentation was observed in 26.7% cases on the first follow up visit. At the end of 4th week with tacrolimus ointment in the next visit, it was perceptible in 15 cases 50.1% and after 12 weeks of therapy 83.3% yielded repigmentation. Among those who had repigmentation, 20% had > 75% repigmentation, 23.3% had 50-75% repigmentation. The percentage of repigmentation on head and neck (83.3%) was greater than that on extremities (55.6%). Complete (>75%) repigmentation was 33.3% cases on head and neck and 26.7% along with extremities. A total of 83.3% cases had some repigmentation and among them, 10 cases had focal presentation and 15 cases had generalised or segmental presentation. There was statistically significant (p<0.005) difference observed between presentation and pigmentation. By using topical steroid minimum side effects like pruritus in 6.7% cases and burning in 10% cases were evidenced. This study reflects that tacrolimus ointment 0.1% is an effective topical therapeutic option for vitiligo especially on the head and neck region with minimum side effects. CBMJ 2014 January: Vol. 03 No. 01 P: 4-7

2017 ◽  
Vol 25 (3) ◽  
pp. 148-153 ◽  
Author(s):  
Rupanjita Sangma ◽  
Mukul Patar

Introduction Haemangiomas are common presentation in head and neck, prevalence being 60% followed by 25% and 15% respectively in trunk and limbs. This report studies the efficacy of Polidocanol as sclerosant in the treatment of heamangiomas in head and neck. Materials and Methods The two year prospective study conducted from January 2015 to December 2016 with Polidocanol as sclerosant on 55 patients attending the department of ENT. Intralesional injections of 3 % polidocanol were given at 2 week intervals. Results Out of 55 patients 15 cases did not follow up after the first dose, so results were calculated out of 40 patients. 12 patients showed complete regression & 15 showed regression to half the size. Thus 67.5 % patients showed acceptable results. There were no side effects except hyperpigmentation in 2 patients. There were no cases of recurrence during our study period. Conclusion Sclerotherapy is a promising method of treatment for haemangiomas of head and neck that may obviate the need for surgical intervention.


2021 ◽  
Vol 14 (5) ◽  
pp. e237083
Author(s):  
Muhammad Hammad Deewani ◽  
Muhammad Hassan Danish ◽  
Muhammad Sohail Awan ◽  
Nasir Ud Din

Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon soft-tissue malignancy. LGFMS preferentially affects trunks and extremities of young adults; however, occasional cases have been reported in different sites of head and neck region including oral cavity, larynx and oropharynx. LGFMS usually exhibit areas of collagenised and myxoid stroma with appearance of spindle cells in whorling pattern. It is a challenge to diagnose it accurately as most of the time it is misdiagnosed as benign neoplastic entity of spindle cells. There have been only few isolated cases of LGFMS reported in head and neck region and LGFMS originating from the parapharyngeal space has never been reported before. We recently experienced a case of low grade fibomyxoid sarcoma in parapharyngeal space of neck. LGFMS have the propensity to locally recur and to metastasise. Due to its rarity in head and neck region, there are no well-established treatment and follow-up guidelines.


2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Pius Agbenorku

Objective. To identify disabilities caused by Buruli Ulcer Disease (BUD) when it affects the Head and Neck Region (HNR) of patients in endemic areas and suggest possible ways to overcome the complications involved. Methods. Data for the study was collected from six different hospitals in the central part of Ghana from 2004–2009. Diagnosis of BUD was based on clinical findings and confirmed by positive result of Ziehl-Neelson Test for Acid Fast Bacilli, Polymerase Chain Reaction, or Histopathology. Treatment of BUD involved a combination of surgical interventions and antimycobacterial chemotherapy for 8 weeks. Results. The age of the 38 patients ranged from 0–56 years (mean age of 14.3 years), with males outnumbering females. Most (55.3%, ) of the patients reported to the facilities with developed BUD deformities. Patients who lost their eyeball () recorded the highest in terms of functional disability. A mean total hospital stay of 52 days and follow-up period of 2.3 years were recorded for the study. Conclusion. Visual impairment was the commonest form of disability recorded in the HNR. Management difficulties and BUD disabilities could be avoided by early detection of the disease and training of health professionals at district levels.


2011 ◽  
Vol 6 (1) ◽  
pp. 125 ◽  
Author(s):  
Jeremias Hey ◽  
Juergen Setz ◽  
Reinhard Gerlach ◽  
Martin Janich ◽  
Guido Hildebrandt ◽  
...  

2011 ◽  
Vol 3 (2) ◽  
pp. 122-124 ◽  
Author(s):  
S Lakshmi ◽  
KG Somashekara ◽  
NS Priya

ABSTRACT Introduction Epidermoid cyst is a rare cyst in head and neck region. We report a case of epidermoid cyst of tongue presented in a girl child. Case report A female child presented with a swelling in her tongue. The swelling was excised completely. A diagnosis of epidermoid cyst of tongue was made. The diagnosis was confirmed by histopathology. There was no recurrence after 6 months follow-up. Conclusion Epidermoid cyst of tongue is a rare tumor of tongue. Complete excision does not cause recurrence.


2016 ◽  
Vol 5 (1) ◽  
pp. 32-35
Author(s):  
T. Adjeso ◽  
E. Siale ◽  
Y.N. Agyeman ◽  
O. Owusu-Afriyie

Squamous papilloma in the head and neck region commonly affects the skin, oral mucosa and upper aerodigestive tract. Ear canal papillomas are relatively rare worldwide, even more uncommon in the West African subregion. We report a twenty year old Ghanaian male seen with ear canal papilloma at our clinic in Kumasi, Ghana. Diagnosis was essentially by histopathology and follow up revealed no recurrence.Journal of Medical and Biomedical Sciences (2016) 5(1), 32-35Keywords: Cauliflower mass, Squamous Papilloma, KATH, Ghana


2021 ◽  
Vol 07 (03) ◽  
pp. e195-e198
Author(s):  
Sapna Dhiman ◽  
Sarita Negi ◽  
Sandeep Moudgil ◽  
Jagdeep S. Thakur ◽  
Ramesh K. Azad

Abstract Background Synovial sarcoma is an aggressive soft tissue cancer of extremities mainly and rare in head and neck region, whereas rarest in ethmoidal sinus as only three cases have been reported till date. Case Reports We managed two cases of synovial sarcoma who presented with nasal obstruction, epistaxis, and swelling around the nasofacial region. Endoscopic nasal biopsy and immunohistochemistry markers confirmed synovial sarcoma in both the cases. While one case was managed by surgery and chemoradiation, the second patient received two cycles of ifosfamide-based chemotherapy and succumbed after 6 weeks of diagnosis. Conclusion Head and neck sarcomas are aggressive and carry a poor prognosis. Surgical resection with postoperative radiotherapy is the standard treatment. However, they have a high risk of recurrence and hence aggressive management and close follow-up is warranted for the optimal outcome.


2002 ◽  
Vol 81 (1) ◽  
pp. 36-39 ◽  
Author(s):  
Levent Saydam ◽  
Ahmet Kizilay ◽  
M. Tayyar Kalcioglu ◽  
Bulent Mizrak ◽  
Fatih Bulut

Synovial sarcoma is a malignancy not usually encountered in the head and neck region. We describe a case of synovial sarcoma of the posterior pharyngeal wall in a 14-year-old girl. The mass was completely excised via the transoral route. Postoperatively, the patient received irradiation to 60 Gy. At 40 months of follow-up, the patient remains disease-free.


1996 ◽  
Vol 110 (10) ◽  
pp. 978-980 ◽  
Author(s):  
K. Gangopadhyay ◽  
M. O. Abuzeid ◽  
H. Kfoury

AbstractHydatid disease is caused by the parasitic tapeworm Echinococcus. This parasite in larval stage can thrive in many parts of the body, most commonly in the liver and the lung. Hydatid disease in the head and neck region is rare. An unusual location for hydatid disease in the pterygopalatine fossa-infratemporal fossa is presented. The patient did not have evidence of any other cyst on a ten-year follow-up.


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