scholarly journals Alteration of Liver Function in Preeclampsia and Eclampsia

2013 ◽  
Vol 12 (3) ◽  
pp. 9-10
Author(s):  
Dilip Kumar Bhowmik ◽  
Rafia Akhtari ◽  
Sadhu Uttam Kumar ◽  
Madhusudan Saha ◽  
Dipal Krishna Adhikary
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Function ◽  
Serum Bilirubin ◽  
Reference Value ◽  
Normal Pregnancy ◽  
Fetal Outcome ◽  
Medical College ◽  
Liver Function Impairment ◽  
Function Impairment ◽  
Normal Reference Value

Introduction: Abnormal liver function in patients with PET and eclampsia affect both maternal and fetal outcome negatively. This study was done to see change of liver function in comparison to normal pregnancy and normal reference value. Methods: Consecutive 47 patients of PET and eclampsia were taken as cases and 35 normal expectant mother were enrolled as controls. ALT, AST, alkaline phosphatase, serum bilirubin, serum creatinine and urine for albumin of patients andnormal pregnant women were tested and compared. Results: ALT, AST, S. Bilirubin, Alkaline phoshatase levels were elevated with more proteinuria among patients with PET and eclampsia, but ALT and alkaline phosphatase levels and level of proteinuria were significantly higher. Conclusions: Liver function impairment is very common in pre-eclampsia and eclampsia.Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 9-10

scholarly journals Study of Liver Function Test in Cirrhotic Patient

2021 ◽  
Vol 28 (2) ◽  
pp. 190-191
Author(s):  
Md Nasir Uddin ◽  
Nur Wa Bushra Jahan ◽  
Kamal Sultan ◽  
Rumana Nushrat ◽  
Md Julfiker Ali ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Function ◽  
Cirrhotic Patient ◽  
Serum Bilirubin ◽  
Income Group ◽  
College Hospital ◽  
Medical College ◽  
Function Test ◽  
Cirrhosis Of Liver ◽  
Medical University

Aim: The study was carried out to see the Serum Bilirubin, ALT, AST and Alkaline Phosphatase as liver function in liver cirrhotic patient. Method: The study was carried out among 50 well-compensated patients of cirrhosis of liver irrespective of their age, sex, residence & income group. Patient was randomly selected while they were hospitalized in Dhaka Medical College Hospital, Sir Salimullah Medical College & Mitford Hospital and Bangabandhu Sheikh Mujib Medical University. Result: Serum Bilirubin, AST, ALT and Alkaline Phosphatase level were done in 50 (fifty) cirrhotic patient out of whom 38 were male and 12 were female. Mild to severe level of serum bilirubin were documented in 50% patients. Two-fold and fourfold rise of ALT were formed in 48% and 10% cirrhotic patient respectively. Similar pattern of rise of AST also shown in 50% cirrhotic patient. Alkaline Phosphatase value was normal in 92% patient and of 08% two-fold rise of Alkaline Phosphatase Alkaline Phosphatase. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 190-191

Reverse flow in intrahepatic portal vessels and liver function impairment in cirrhosis

1997 ◽  
Vol 6 (3) ◽  
pp. 171-177 ◽  
Author(s):  
L Tarantino ◽  
A Giorgio ◽  
G de Stefano ◽  
N Mariniello ◽  
A Perrotta ◽  
...  
Keyword(s):  
Liver Function ◽  
Reverse Flow ◽  
Liver Function Impairment ◽  
Function Impairment

scholarly journals Study of thyroid hormones in pregnancy

2020 ◽  
Vol 9 (10) ◽  
pp. 4086
Author(s):  
Madhu Juneja ◽  
Salil Barsode ◽  
Tushar Panchanadikar
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
Tertiary Care ◽  
Normal Pregnancy ◽  
Fetal Outcome ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Disorder ◽  
Medical College ◽  
Systemic Examination ◽  
A Prospective Study

Background: Thyroid disorder is often overlooked in pregnant women this is because of nonspecific symptoms and hyper metabolic state of normal pregnancy. To evaluate the thyroid function in pregnant women in all the three trimesters and to study their impact on pregnancy outcome.Methods: A prospective study in 200 randomly selected antenatal cases was carried out during a period of two years in a tertiary care medical college in Western Maharashtra. A detailed general and systemic examination was carried out and Thyroid stimulating hormone (TSH) was done in all cases. Any case with an abnormal TSH level was further tested for T3 T4 levels.Results: The mean TSH level was 1.6 µIU/l which was less than the standard cut off of 2.5 µIU/l. 61% had decreasing level of TSH with advanced gestation. An abnormal thyroid function was seen in 8.5% cases.Conclusions: Standardization of TSH, T3, T4 is still a concern as it varies significantly in different studies. Estimation of TSH with T3 T4 could not be correlated during pregnancy with advancing gestational age. The real impact of hypo/hyperthyroidism on fetal outcome could not be statistically established.

scholarly journals Liver synthesis function in chronic asymptomatic or oligosymptomatic alcoholics: correlation with other liver tests

1999 ◽  
Vol 54 (3) ◽  
pp. 97-102 ◽  
Author(s):  
Paulo Borini ◽  
Romeu Cardoso Guimarães
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Function ◽  
Hepatic Dysfunction ◽  
Serum Bilirubin ◽  
Serum Alkaline Phosphatase ◽  
Nutritional Deficiencies ◽  
Hepatic Enzymes ◽  
Prothrombin Activity ◽  
Gamma Glutamyltransferase ◽  
Liver Tests

Liver function and its correlation with bilirubin and hepatic enzymes were evaluated in 30 male chronic asymptomatic or oligosymptomatic alcoholics admitted into the psychiatric hospital for detoxification and treatment of alcoholism. Hypoalbuminemia, lowered prothrombin activity, hypotransferrinemia and hypofibrinogenemia were detected in 32 %, 32 %, 28 %, and 24 % of patients, respectively. Transferrin was elevated in 8 %. Greater prevalence of hyperbilirubinemia was found in patients with lowered prothrombin activity, hypofibrinogenemia, or hypotransferrinemia. No correlation was found between serum bilirubin or aminotransferase levels and normal or elevated albumin levels, time or activity of prothrombin, and fibrinogen levels. Serum alkaline phosphatase was elevated in normoalbuminemics and gamma-glutamyltransferase in patients with lowered prothrombin activity. Hypoalbuminemia was associated with hypofibrinogenemia, hypotransferrinemia with elevated aspartate aminotransferase or gamma-glutamyltransferase, and hypertransferrinemia with elevation of alanine aminotransferase. These data indicated the occurrence of hepatic dysfunction due to liver damage caused directly by alcohol or by alcoholism-associated nutritional deficiencies.

Individual diagnosis of chemotherapy-associated liver function impairment before surgery of hepatic colorectal metastases

2017 ◽  
Vol 72 ◽  
pp. S65
Author(s):  
J.F. Lock ◽  
T. Westphal ◽  
M. Malinowski ◽  
M. Jara ◽  
J. Bednarsch ◽  
...  
Keyword(s):  
Liver Function ◽  
Colorectal Metastases ◽  
Liver Function Impairment ◽  
Function Impairment

scholarly journals The feasibility of transcatheter arterial chemoembolization following radiation therapy for hepatocellular carcinoma

2021 ◽  
Vol 10 (7) ◽  
pp. 205846012110349
Author(s):  
Mostafa Hamada ◽  
Eisuke Ueshima ◽  
Takeaki Ishihara ◽  
Yutaka Koide ◽  
Takuya Okada ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Function ◽  
Transcatheter Arterial Chemoembolization ◽  
Survival Duration ◽  
High Dose ◽  
Short Term ◽  
Liver Function Impairment ◽  
Function Impairment ◽  
Short Term Mortality ◽  
Arterial Chemoembolization

Background Technological developments have led to an increased usage of external-body radiotherapy (RT) for the treatment of hepatocellular carcinoma (HCC). Transcatheter arterial chemoembolization (TACE) may be required later in patients treated with RT because of the high recurrence rate and multinodular presentation of HCC. However, despite the risk of liver function impairment, the cumulative liver damage correlated with TACE following a hepatic RT has not been adequately assessed. Purpose To evaluate the feasibility of TACE following RT for HCC. Materials and methods Sixty-seven patients with HCC who underwent TACE after RT were retrospectively evaluated between 2012 and 2018. We assessed increases in Child–Turcotte–Pugh (CTP) by ≥2 points at 1 month, the incidence of major complications, survival duration, and short-term mortality within 6 months after TACE. Furthermore, we evaluated the predictive factors for liver function impairment and short-term mortality. Results Eight patients experienced a CTP increase ≥2 points at 1 month. There were no cases of liver abscesses or bilomas. Nine patients died within 6 months following TACE. The mean liver dose (MLD) was a significant predictor of liver function impairment at 1 month ( p = 0.042). Low liver functional reserve, distant metastasis ( p = 0.037), MLD ( p = 0.046), TACE type ( p = 0.025), and TACE within 3 months following RT ( p = 0.007) were significant predictors of short-term mortality. Conclusions Despite the feasibility of TACE following RT, clinicians should pay attention to impaired pretreatment liver function, following high dose RT, and the short duration between RT and TACE.

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