scholarly journals Prevalence of Metabolic Syndrom in Three Urban Communities of Dhaka City

1970 ◽  
Vol 2 (2) ◽  
pp. 44-48 ◽  
Author(s):  
Shurovi Sayeed ◽  
Akhter Banu ◽  
Parvin Akter Khanam ◽  
Sharmina Alauddin ◽  
Sabrina Makbul ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Urban Communities ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Urban Population ◽  
Population Characteristics ◽  
Dhaka City ◽  
Fasting Plasma ◽  
Prevalence Of Obesity ◽  
The Mean

Bangladeshis are prone to develop type 2 diabetes mellitus (T2DM), hypertension (sHTN and dHTN) and atherosclerotic heart diseases, observed more predominantly in the urban population. Though metabolic syndrome (MetS) is a related disorder, there are few studies in this regard. The prevalence of obesity, T2DM and MetS in three urban communities of Bangladesh were addressed in this study. Nine hundred non-slum urban households in three Dhaka City Wards were randomly selected. One member (age ≥ 25y) from each household was invited for investigation with an overnight fast. Socio-demographic information as well as height, weight, waist-girth, hip-girth and blood pressure were measured. Fasting plasma glucose (FPG), total cholesterol (chol), triglycerides (TG) and high-density lipoproteins-c (HDL) were estimated. A total of 705 (m / f = 239 / 466) subjects volunteered for the study. The mean value with 95% confidence interval (CI) of age was 42.4 (40.9 - 43.1) years for men and 37.8 (36.8 - 38.7) for women. The mean (CI) body mass index (BMI) was 21.0 (20.6 - 21.5) and 22.6 (22.2 - 22.9) and waist hip ratio (WHR) was 0.84 (0.83 - 0.84) and 0.82 (0.81 - 0.83), respectively for men and women. The mean (CI) FPG (fasting plasma glucose) was 5.5 (5.2 - 5.7) for men and 5.2 (5.0 - 5.4) for women. The prevalence of obesity (BMI ≥ 25.0) was 21%, T2DM (FPG ≥ 6.1 mmol/l) was 22.2%, triglyceridemia (TG ≥ 150mg/dl) was 45.1% and low HDL-c (HDL<40mg/ dl) was 43.8%. The crude prevalence of MetS varied based on different cluster combinations, being the lowest (0.3%) recommended by WHO cluster (FPG + BMI + SBP/DBP) and the highest (8.7%) by International Diabetes Federation (IDF) cluster (waist + FPG + HDL). The MetS was found higher in male than female by NCEP criteria and higher in female than male by IDF criteria. The study revealed an increased prevalence of obesity, T2DM and MetS in the urban communities. It also revealed that T2DM and MetS are moderately common and of growing healthcare burden in the rapidly growing urban population. Additionally, the study observed the wide ranging prevalence rates of MetS in the same study population indicating the need to establish a consistent and useful MetS-cluster depending on population characteristics. Ibrahim Med. Coll. J. 2008; 2(2): 44-48 Key Words: Metabolic syndrome, urban, diabetes, hypertension, dyslipidemia   doi: 10.3329/imcj.v2i2.2936

Fasting plasma glucose control among nigerians with metabolic syndrome.

2008 ◽  
Vol 5 (1) ◽  
Author(s):  
O S Adediran ◽  
O A Fasanmade ◽  
O A Ogbera ◽  
A E Ohwovoriole
Keyword(s):  
Metabolic Syndrome ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glucose Control ◽  
Fasting Plasma

scholarly journals Metabolic Syndrome in Female Patients with Acute Myocardial Infarction

2018 ◽  
Vol 26 ◽  
pp. 74-78
Author(s):  
MMR Khan ◽  
Niranjan Kumar Sana ◽  
M Rais Uddin ◽  
M Rahman ◽  
M Zahirul Haque ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Metabolic Syndrome ◽  
Acute Myocardial Infarction ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Age Group ◽  
Female Patients ◽  
The Metabolic Syndrome ◽  
Fasting Plasma ◽  
Low Hdl

Introduction and objectives: A large proportion of patients with coronary disease have metabolic syndrome. The purpose of this research was to assess the association between the metabolic syndrome (MetS) and acute myocardial infarction in female patients.Methods: This was a case control study. Patients with a first time cardiac event of acute myocardial infarction (AMI) arriving in coronary care unit of Rajshahi Medical College Hospital, Rajshahi, Bangladesh during the period June 2013 to July 2014 were included. Metabolic syndrome and its five components were defined according to criteria set by Adult Treatment Plan III (NCEP ATP III) criteria. Blood sugars, triglycerides, HDL-C were measured within 24hrs of cardiac insult. Hypertension was defined as blood pressure ≥ 130/≥85 mmHg. Abdominal obesity measured by waist circumference which is defined for Asia-Pacific region as ≥ 80 cm for women.Results: Total 103 female patients were evaluated. Mean age was 54.28 ±11.78 and acute myocardial infarction was more in age group 50-59 (34%). More than 60% patients suffering from acute myocardial infarction was age group 40-60 years. The metabolic syndrome was present in 74 (71.8%) female patients with acute myocardial infarction and was more frequent in women than in men (71.8% vs 37.9%, P<.001). The most prevalent component was low HDL-C (n 76; 73.8%), followed by fasting plasma glucose level (n 73; 70.9%).Conclusions: The metabolic syndrome has a high prevalence in female patients with acute myocardial infarction. The most frequent components are low HDL-C levels and fasting plasma glucose level.TAJ 2013; 26: 74-78

scholarly journals Investigation of Fasting Plasma Glucose in Masters Athletes

2020 ◽  
Vol 4 (2) ◽  
pp. 65-68
Author(s):  
Joe Walsh ◽  
◽  
Ian Timothy Heazlewood ◽  
Mark DeBeliso ◽  
Mike Climstein ◽  
...  
Keyword(s):  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Sport Participation ◽  
Past Research ◽  
Fasting Plasma ◽  
Age Related ◽  
Significant Difference ◽  
Masters Athletes ◽  
The Mean ◽  
The Difference

Prior research documented differences in fasting plasma glucose (FPG) between older and younger masters athletes at the Golden Oldies Rugby Festival (GORF). It was the purpose of our study to further investigate FPG on a larger sample. FPG data was collected on 486 participants at the Sydney World Masters Games. Of the males, 241 reported optimal FPG and 36 reported sub-optimal FPG. For females 183 reported optimal FPG and 26 reported sub-optimal FPG. Analysis was conducted utilising the age ranges implemented in past research on the GORF. The mean FPG for masters athletes below 50 years old was 5.10±1.52 mmol/L, whilst for those 50 years and above it was 5.01±1.02. The difference between the groups was not significant (t = 0.722, p = 0.471). This aligned with the finding of the GORF study that there was no significant difference in FPG between the different age ranges analysed. The sample size obtained for this investigation of FPG in masters athletes was more than double the number of participants used in previous research on the GORF. Many participants had FPG above optimal levels. Therefore, an age-related decline in pancreatic function may outweigh protective exercise benefits attained from masters sport participation.

scholarly journals Effect of Sample Volume Variation and Delay in Analysis on Plasma Glucose Concentration in Sri Lankan Healthy Adults

Scientifica ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Isuru Anupama Dharmasena ◽  
Deepani Siriwardhana ◽  
Anoja Priyadarshani Attanayake
Keyword(s):  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glucose Concentration ◽  
Sample Volume ◽  
Healthy Adults ◽  
Plasma Glucose Concentration ◽  
Volume Variation ◽  
Fasting Plasma ◽  
Dependent Change ◽  
The Mean

The correct volume of sample and time of storing prior to the analysis are important considerations in the estimation of plasma glucose concentration of patients. The present study was to determine the effect of sample volume variation and time delay in the analysis of plasma glucose results in healthy adults. A total of 30 individuals aged between 20 and 30 years were selected for the study. Blood samples were collected into three fluoride-oxalate collection tubes separately. The results revealed that the sample volume variation from 2.0 mL fluoride-oxalate tube to 1.0 mL and 3.0 mL did not significantly affect the plasma glucose concentration ( p  > 0.05). However, the plasma glucose concentration in the sample significantly decreased upon delaying the analysis. The mean fasting plasma glucose concentration of analysis after one hour of collection and analysis after three hours of collection was not significantly different ( p  > 0.05). The mean fasting plasma glucose concentrations between one hour and five hours timepoints after collection ( p  < 0.001) and between three hours and five hours after collection ( p  = 0.014) were significantly different. In conclusion, overfilling and underfilling (2.0 ± 1.0 mL) of fluoride-oxalate tubes did not affect the plasma glucose results significantly. If the samples are analyzed within three hours of collection, the time dependent change too is not statistically significant.

scholarly journals Effect of telmisartan on selected adipokines, insulin sensitivity, and substrate utilization during insulin-stimulated conditions in patients with metabolic syndrome and impaired fasting glucose

2010 ◽  
Vol 163 (4) ◽  
pp. 573-583 ◽  
Author(s):  
Petr Wohl ◽  
Eva Krušinová ◽  
Martin Hill ◽  
Simona Kratochvílová ◽  
Kateřina Zídková ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Insulin Sensitivity ◽  
Impaired Fasting Glucose ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Fasting Glucose ◽  
Substrate Utilization ◽  
Metabolic Effects ◽  
Plasma Adiponectin ◽  
Fasting Plasma

ObjectiveTelmisartan improves glucose and lipid metabolism in rodents. This study evaluated the effect of telmisartan on insulin sensitivity, substrate utilization, selected plasma adipokines and their expressions in subcutaneous adipose tissue (SAT) in metabolic syndrome.Design and methodsTwelve patients with impaired fasting glucose completed the double-blind, randomized, crossover trial. Patients received telmisartan (160 mg/day) or placebo for 3 weeks and vice versa with a 2-week washout period. At the end of each period, a hyperinsulinemic euglycemic clamp (HEC) combined with indirect calorimetry was performed. During HEC (0, 30, and 120 min), plasma levels of adipokines were measured and a needle biopsy (0 and 30 min) of SAT was performed.ResultsFasting plasma glucose was lower after telmisartan compared with placebo (P<0.05). There were no differences in insulin sensitivity and substrate utilization. We found no differences in basal plasma adiponectin, resistin and tumour necrosis factor α (TNFα), but an increase was found in basal leptin, after telmisartan treatment. Insulin-stimulated plasma adiponectin (P<0.05), leptin and resistin (P<0.001) were increased, whereas TNFα was decreased (P<0.05) after telmisartan treatment. Expression of resistin, but not adiponectin, TNFα and leptin was increased after telmisartan treatment.ConclusionsDespite the decrease in fasting plasma glucose, telmisartan does not improve insulin sensitivity and substrate utilization. Telmisartan increases plasma leptin as well as insulin-stimulated plasma adiponectin, leptin and resistin, and decreases plasma TNFα during HEC. Changes in plasma adipokines cannot be explained by their expressions in SAT. The changes in plasma adipokines might be involved in the metabolic effects of telmisartan in metabolic syndrome.

Size of myocardial infarction induced by ischaemia/reperfusion is unaltered in rats with metabolic syndrome

2006 ◽  
Vol 110 (6) ◽  
pp. 665-671 ◽  
Author(s):  
Troels Thim ◽  
Jacob F. Bentzon ◽  
Steen B. Kristiansen ◽  
Ulf Simonsen ◽  
Heidi L. Andersen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Metabolic Syndrome ◽  
Infarct Size ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Metabolic Disturbances ◽  
The Metabolic Syndrome ◽  
Fasting Plasma

Obesity is associated with metabolic syndrome and increased incidence of and mortality from myocardial infarction. The aim of the present study was to develop an animal model with metabolic syndrome and examine how that influences size of myocardial infarcts induced by occlusion and reperfusion of the left anterior descending coronary artery. Sprague–Dawley rats (n=105) were fed either LF (low-fat) or MHF (moderately high-fat) diets for 13 weeks before coronary occlusion for 45 min, followed by reperfusion for 60 min. Compared with LF-fed and lean MHF-fed rats, obese MHF-fed rats developed metabolic disturbances similar to those seen in the metabolic syndrome, including being overweight by 24% (compared with lean MHF-fed rats), having 74% more visceral fat (compared with LF-fed rats), 15% higher blood pressure (compared with LF-fed rats), 116% higher plasma insulin (compared with lean MHF-fed rats), 10% higher fasting plasma glucose (compared with LF-fed rats), 35% higher non-fasting plasma glucose (compared with lean MHF-fed rats), 36% higher plasma leptin (compared with lean MHF-fed rats) and a tendency to lower plasma adiponectin and higher plasma non-esterified fatty acids. Infarct size was similar in the three groups of rats (36±14, 42±18 and 41±14% in obese MHF-fed, lean MHF-fed and LF-fed rats respectively). In conclusion, rats fed a MHF diet developed metabolic syndrome, but this did not influence myocardial infarct size.

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