Power Spectral Analysis of Heart Rate Variability in Female Rheumatoid Arthritis Patients

Background: Association of increased cardiovascular morbidity and higher sympathetic activity in patients with Rheumatoid arthritis (RA) has been recognized. Heart rate variability (HRV) is a useful measure to assess sympatho-vagal balance.Objective: To assess autonomic nerve function status in patients with Rheumatoid Arthritis (RA) by HRV analysis.Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from January to December 2010. Sixty female RA patients aged 18-50 years were included in the study group. They were enrolled from the Out Patient Department of Rheumatology Wing of the Department of Medicine, BSMMU, Dhaka. For comparison age matched thirty apparently healthy females were also studied as control. The HRV parameters were recorded by a Polyrite machine. For statistical analysis independent sample t test was used.Results: Mean resting pulse rate, diastolic blood pressure and mean systolic blood pressure were higher in rheumatoid arthritis patients in comparison to those of healthy control. Mean values of LF power, LF norm and LF/ HF were significantly higher (p<0.001) & TP and HF power, HF norm were significantly lower (p<0.001) in RA patients in comparison to those of healthy control.Conclusion: This study may conclude that sympathetic activity was higher with lower parasympathetic activity along with shifting of sympathovagal balance towards sympathetic predominance in patients with rheumatoid arthritis. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11153 J Bangladesh Soc Physiol. 2012, June; 7(1): 8-12

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Heart Rate Variability in Patients with Rheumatoid Arthritis

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v7i2.14455 ◽

2013 ◽

Vol 7 (2) ◽

pp. 78-82 ◽

Cited By ~ 2

Author(s):

Kawser Jahan ◽

Noorzahan Begum ◽

Sultana Ferdousi

Keyword(s):

Rheumatoid Arthritis ◽

Heart Rate ◽

Heart Rate Variability ◽

Time Domain ◽

Cross Sectional Study ◽

Autonomic Nerve ◽

Nerve Function ◽

Activity Data ◽

Cross Sectional ◽

Autonomic Nerve Function

Background: Altered cardiovascular autonomic nerve function with impaired sympathovagal balance is found in rheumatoid arthritis (RA). Heart Rate Variability (HRV) analysis is an important tool for assessment of autonomic nerve activity. Objective: To assess cardiac autonomic nerve function status in patients with Rheumatoid arthritis (RA) by time domain measures of HRV. Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from January to December 2010. Sixty female RA patients, age range 18-50 years were constituted study group enrolled from the Out- patient Rheumatology Wing, Department of Medicine, BSMMU. Age matched thirty apparently healthy females were studied as control. Time domain measures of Heart Rate Variability (HRV) such as Mean RR intervals, Mean HR, SDNN, RMSSD, NN50% and PNN 50% were recorded for 5 minutes by a Polygraph machine to observe cardiac autonomic nerve function activity. Data were analyzed by independent sample t test. Results: Mean R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower (p<0.001) but heart rate was significantly (P<0.001) higher in rheumatoid arthritis patients. Conclusion: Cardiac autonomic nerve function is impaired and characterized by reduced resting parasympathetic activity in female Rheumatoid Arthritis patients. DOI: http://dx.doi.org/10.3329/jbsp.v7i2.14455 J Bangladesh Soc Physiol. 2012, December; 7(2): 78-82

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Power spectral analysis of heart rate variability in Bangladeshi healthy population of different age

Bangladesh Journal of Physiology and Pharmacology ◽

10.3329/bjpp.v30i1.20788 ◽

2014 ◽

Vol 30 (1) ◽

pp. 11-15

Author(s):

Qazi Farzana Akhter ◽

Qazi Shamima Akhter ◽

Farhana Rahman ◽

Sybyla Ferdousi ◽

Susmita Sinha

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Spectral Analysis ◽

Power Spectral Analysis ◽

Autonomic Nerve ◽

Total Power ◽

Healthy Population ◽

Cross Sectional ◽

Power Spectral ◽

Group A

Heart rate variability (HRV) has been considered as an indicator of autonomic nerve function status. We aimed to find out the reference values of heart rate variability by power spectral analysis in our healthy population of different age. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this, 180 subjects were selected with the age ranging from 15-60 years. All the study subjects were divided into 3 different groups according to age (Group A: 15-30 years; Group B: 31-45 years; Group C: 46-60 years). Each group contained 60 subjects of which 30 were male and 30 were female. The subjects were selected from different areas of Dhaka city by personal contacts. Analysis of HRV parameters were done in Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. For statistical analysis, one way ANOVA, unpaired Students t-test and Pearsons correlation coefficient test were performed by using SPSS (version-17) as applicable. LF nu, LF power and LF/HF were significantly (p<0.001) higher in group C in comparison to those of group A and B. Again Total power, HF power, HF nu (p<0.001) were significantly higher in group A and B in comparison to that of group C. This study concludes that cardiac parasympathetic activity was decreased and sympathetic activity was increased with aging.DOI: http://dx.doi.org/10.3329/bjpp.v30i1.20788 Bangladesh J Physiol Pharmacol 2014; 30(1):11-15

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Effect of Aging on Short Term Heart Rate Variability

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v9i2.22801 ◽

2015 ◽

Vol 9 (2) ◽

pp. 78-82 ◽

Cited By ~ 1

Author(s):

Qazi Farzana Akhter ◽

Qazi Shamima Akhter ◽

Farhana Rohman ◽

Susmita Sinha ◽

Sybilla Ferdousi

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Heart Rate Variability ◽

Healthy Subjects ◽

Middle Age ◽

Older Age ◽

Autonomic Nerve ◽

Age Group ◽

Nerve Function ◽

Autonomic Nerve Function

Background: Heart rate variability has been considered as an indicator of autonomic nerve function status. Few works have been done to assess the heart rate variability in normal healthy subjects in different countries. Objectives: To assess the cardiac autonomic nerve function status in healthy Bangladeshi population of different age groups by analyzing time domain measures of Heart Rate Variability. Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this purpose, a total number of 180 healthy subjects were selected with the age ranging from 15-60 years of both sexes. All the study subjects were divided into 3 different groups according to age (Control 15-30 years; middle age 31-45 years; older age 46-60 years). Each group included 60 subjects of which 30 were male and 30 were female. The subjects were selected from different areas of Dhaka city by personal contacts. HRV parameters were recorded by a 4 active channels, RMS Polyrite-D-2 machine For statistical analysis, one way ANOVA, unpaired Students t-test and Pearsons correlation coefficient test were performed. as applicable. Results: Systolic blood pressure (SBP), diastolic blood pressure (DBP) were significantly (p<0.001) higher in older group in comparison to control & middle age group. Again RR interval and RMSSD (p<0.001), were significantly lower in older age group (p<0.05) compared to control & also to middle age group. But HR was found significantly higher (p<0.05)in both middle and older subjects than control and also in older (p<0.05) compared to middle age. Correlation analysis showed moderate negative correlation of mean R-R with age in middle age whereas significant negative correlation for RMSSD both in middle and older age subjects. Conclusion: In this study, markedly decreased cardiac parasympathetic function were found with aging process. DOI: http://dx.doi.org/10.3329/jbsp.v9i2.22801 Bangladesh Soc Physiol. 2014, December; 9(2): 78-82

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Power spectral analysis of heart rate variability in Bangladeshi healthy male and female

Bangladesh Medical Journal ◽

10.3329/bmj.v43i3.26298 ◽

2016 ◽

Vol 43 (3) ◽

pp. 146-150

Author(s):

Qazi Farzana Akhter ◽

Qazi Shamima Akhter ◽

Farhana Rahman ◽

Sybilla Ferdousi ◽

Susmita Sinha

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Heart Rate Variability ◽

Spectral Analysis ◽

High Frequency ◽

Low Frequency ◽

Power Spectral Analysis ◽

Autonomic Nerve ◽

Age Group ◽

Power Spectral

Heart rate variability (HRV) has been considered as an indicator of autonomic nerve function status. We aimed to find out the reference values of heart rate variability by power spectral analysis in our healthy population of both sex. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this, 180 subjects were selected with the age ranging from 15-60 years. All the study subjects were divided into 3 different groups according to age (Group A: 15-30 years; Group B: 31-45 years; Group C: 46-60 years). Each group contained 60 subjects of which 30 were male and 30 were female. Analysis of HRV parameters were done in Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Systolic blood pressure, diastolic blood pressure, low frequency normalized unit, low frequency / high frequency ratio were significantly higher in male than female. Again high frequency power, high frequency normalized unit were significantly higher in female than male of same age group. This study concludes that male showed higher cardiac sympathetic activities while female showed higher cardiac parasympathetic activities in different age groups.Bangladesh Med J. 2014 Sep; 43 (3): 146-150

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Heart Rate Variability in Shift Workers: Responses to Orthostatism and Relationships with Anthropometry, Body Composition, and Blood Pressure

BioMed Research International ◽

10.1155/2015/329057 ◽

2015 ◽

Vol 2015 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

Nayara Mussi Monteze ◽

Breno Bernardes Souza ◽

Henrique José de Paula Alves ◽

Fernando Luiz Pereira de Oliveira ◽

José Magalhães de Oliveira ◽

...

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Heart Rate Variability ◽

Body Composition ◽

Cross Sectional Study ◽

Visceral Fat Area ◽

Cross Sectional ◽

Shift Workers ◽

Mean Values ◽

Orthostatic Position

In order to investigate the response of heart rate variability (HRV) components to postural change and their association with cardiovascular risk factors in shift workers, a cross-sectional study with 438 Brazilian males rotating shift workers was done. Anthropometric, body composition, and clinical measures were collected. Electrocardiogram was recorded for 3 minutes, in the supine and orthostatic position, and HRV components were extracted. Descriptive analyses showed that mean values of body mass index, waist circumference (WC), waist-to-height ratio, visceral fat area (VFA), and blood pressure (BP) were higher than the reference values. In the regression model, age, WC, VFA, and systolic BP showed negative association with HRV components. These findings suggest the need for determining effective strategies for the evaluation and promotion of health among shift workers focused on the altered variables.

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Parasympathetic Nerve Function Status in Female with Rheumatoid Arthritis

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v8i1.16643 ◽

2013 ◽

Vol 8 (1) ◽

pp. 21-25

Author(s):

Kawser Jahan ◽

Noorzahan Begum ◽

Sultana Ferdousi

Keyword(s):

Rheumatoid Arthritis ◽

Heart Rate ◽

Heart Rate Response ◽

Valsalva Maneuver ◽

Autonomic Nerve ◽

Nerve Function ◽

Deep Breathing ◽

Cross Sectional ◽

Parasympathetic Nerve ◽

Mean Values

Background: Sudden cardiac death in patients with Rheumatoid Arthritis has been attributed to the decreased vagal drive to the heart. Objective: To assess cardiac parasympathetic nerve function status in patients with Rheumatoid Arthritis (RA). Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from January to December 2010. Sixty female RA patients aged 18-50 years were included in the study group. They were enrolled from the Out Patient Department of Rheumatology Wing of the Department of Medicine, BSMMU, Dhaka. For comparison age matched thirty apparently healthy females were also studied as control. To assess parasympathetic nerve function status, all the subjects were examined by three noninvasive cardiovascular reflex tests such as heart rate response to valsalva maneuver (valsalva ratio), heart rate response to deep breathing and heart rate response to standing (30th :15th ratio). For statistical analysis independent sample t test was used. Results: Mean values of valsalva ratio, deep breathing test and 30th :15th ratio were significantly (p<0.001) lower in rheumatoid arthritis patients compared to those of healthy control. Conclusion: From this study it may be concluded that lower cardiac parasympathetic nerve activity characterized the autonomic nerve dysfunction in patients with Rheumatoid Arthritis. DOI: http://dx.doi.org/10.3329/jbsp.v8i1.16643 J Bangladesh Soc Physiol. 2013, June; 8(1): 21-25

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