scholarly journals Heart Rate Variability in Patients with Rheumatoid Arthritis

2013 ◽  
Vol 7 (2) ◽  
pp. 78-82 ◽  
Author(s):  
Kawser Jahan ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Rheumatoid Arthritis ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Time Domain ◽  
Cross Sectional Study ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Activity Data ◽  
Cross Sectional ◽  
Autonomic Nerve Function

Background: Altered cardiovascular autonomic nerve function with impaired sympathovagal balance is found in rheumatoid arthritis (RA). Heart Rate Variability (HRV) analysis is an important tool for assessment of autonomic nerve activity. Objective: To assess cardiac autonomic nerve function status in patients with Rheumatoid arthritis (RA) by time domain measures of HRV. Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from January to December 2010. Sixty female RA patients, age range 18-50 years were constituted study group enrolled from the Out- patient Rheumatology Wing, Department of Medicine, BSMMU. Age matched thirty apparently healthy females were studied as control. Time domain measures of Heart Rate Variability (HRV) such as Mean RR intervals, Mean HR, SDNN, RMSSD, NN50% and PNN 50% were recorded for 5 minutes by a Polygraph machine to observe cardiac autonomic nerve function activity. Data were analyzed by independent sample t test. Results: Mean R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower (p<0.001) but heart rate was significantly (P<0.001) higher in rheumatoid arthritis patients. Conclusion: Cardiac autonomic nerve function is impaired and characterized by reduced resting parasympathetic activity in female Rheumatoid Arthritis patients. DOI: http://dx.doi.org/10.3329/jbsp.v7i2.14455 J Bangladesh Soc Physiol. 2012, December; 7(2): 78-82

scholarly journals Impaired Cardiac Vagal Tone in Patients with Major Depressive Disorder

2016 ◽  
Vol 10 (2) ◽  
pp. 41-45
Author(s):  
Choudhury Rifat Jahan ◽  
Shelina Begum ◽  
Sultana Ferousi ◽  
Md Moyeen Uddin
Keyword(s):  
Heart Rate ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Vagal Tone ◽  
Cross Sectional Study ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Major Depressive ◽  
Cross Sectional ◽  
Autonomic Nerve Function

Background: Altered cardiovascular autonomic nerve function with impaired autonomicl balance is found in Major Depressive Disorder(MDD).Objective: To assess some time domain measures of Heart Rate Variability (HRV) in MDD patients to observe their autonomic nerve function status.Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, during 2011on 60 patients of both sexes with Major Depressive disorder (MDD) aged 20-50 years. They were further subdivided into 30 drug naïve and 30 patients treated with anti depressive drug. Age, sex and BMI matched 30 apparently healthy subjects were control. The HRV parameters were recorded by 4 active channels, Polyrite-D. For statistical analysis ANOVA, independent sample t-test, were performed.Result: Mean R-R interval, SDNN,RMSSD ,PNN50%, NN50% were found significanty lower but heart rate was significantly higher in all MDD patients of both group compared to control.No significant differences were found in these parameters between treated and recently diagnosed patient.Conclusion: Cardiac autonomic nerve function was impaired in MDD patient which was characterized by reduced vagal tone. Antidepressive medication may not have any effect on impaired autonomic function in MDD.Bangladesh Soc Physiol. 2015, December; 10(2): 41-45

scholarly journals Power Spectral Analysis of Heart Rate Variability in Female Rheumatoid Arthritis Patients

2012 ◽  
Vol 7 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Kawser Jahan ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Rheumatoid Arthritis ◽  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Sympathetic Activity ◽  
Power Spectral Analysis ◽  
Autonomic Nerve ◽  
Cross Sectional ◽  
Mean Values ◽  
Autonomic Nerve Function

Background: Association of increased cardiovascular morbidity and higher sympathetic activity in  patients with Rheumatoid arthritis (RA) has been recognized. Heart rate variability (HRV) is a useful  measure to assess sympatho-vagal balance.Objective: To assess autonomic nerve function status in  patients with Rheumatoid Arthritis (RA) by HRV analysis.Methods: This cross sectional study was  conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University  (BSMMU), Shahbag, Dhaka from January to December 2010. Sixty female RA patients aged 18-50  years were included in the study group. They were enrolled from the Out Patient Department of  Rheumatology Wing of the Department of Medicine, BSMMU, Dhaka. For comparison age matched  thirty apparently healthy females were also studied as control. The HRV parameters were recorded by  a Polyrite machine. For statistical analysis independent sample t test was used.Results: Mean resting  pulse rate, diastolic blood pressure and mean systolic blood pressure were higher in rheumatoid  arthritis patients in comparison to those of healthy control. Mean values of LF power, LF norm and LF/  HF were significantly higher (p<0.001) & TP and HF power, HF norm were significantly lower (p<0.001)  in RA patients in comparison to those of healthy control.Conclusion: This study may conclude that  sympathetic activity was higher with lower parasympathetic activity along with shifting of  sympathovagal balance towards sympathetic predominance in patients with rheumatoid arthritis. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11153 J Bangladesh Soc Physiol. 2012, June; 7(1): 8-12

scholarly journals Heart Rate Variability in Patients with Essential Hypertension

1970 ◽  
Vol 5 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Rehnuma Tabassum ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Parasympathetic Nerve ◽  
Hypertensive Patients ◽  
Autonomic Nerve Function ◽  
Normotensive Subjects

Background: Essential hypertension may be associated with altered cardiovascular autonomic nervefunction. Heart Rate Variability (HRV) analysis is an important tool for quantitative measurement ofautonomic nerve activity. Objective: To assess the cardiac autonomic nerve function status in essentialhypertension by analyzing time domain measures of heart rate variability. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib MedicalUniversity from 1st July 2008 to 30th June 2009.For this purpose, 60 hypertensive male patients withage ranged between 40-60 years (group B) were enrolled from the Out Patient Department of Cardiology,BSMMU, Dhaka. Based on treatment received, hypertensive patients were subdivided into group B1i.e.untreated patients on their 1st day of diagnosis and group B2 i.e.patients with antihypertensivetherapy. For comparison, 30 age & sex matched apparently healthy normotensive subjects (group A)were also studied as control group. Time domain measures of Heart Rate Variability (HRV) such asMean RR intervals, Mean HR, SDNN & RMSSD were assessed by a Polygraph machine to observeboth sympathetic and parasympathetic nerve function status. For statistical analysis of data,Independent sample t-test, One-way ANOVA test, were used as applicable. Results: Mean R-R interval SDNN and RMSSD were significantly (P<0.01) lower but mean heart rate was significantly (P<0.01)higher in untreated hypertensive patients than those of normotensive subjects. But differences in allthese 4 parameters when compared between control and treated hypertensive patients were foundstatistically non significant. Conclusion: Impaired cardiac autonomic nerve function characterized bysympathetic overactivity may occur in hypertensive patients.Key words: Mean RR; SDNN; RMSSD; hypertensionDOI: 10.3329/jbsp.v5i1.5411J Bangladesh Soc Physiol. 2010 June; 5(1): 1-7

scholarly journals Time Domain Measures of Heart Rate Variability to Assess Autonomic Dysfunction In Irritable Bowel Syndrome

2013 ◽  
Vol 7 (2) ◽  
pp. 60-65
Author(s):  
Mohammad Nayem ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Irritable Bowel Syndrome ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
Irritable Bowel ◽  
Function Activity ◽  
Mean Heart Rate

Background: Autonomic nerve function impairment is related to development of Irritable Bowel Syndrome (IBS). Time domain measures of Heart rate variability (HRV) is a useful tool to measure autonomic nerve function activity. Objective: To assess autonomic nerve function activity by time domain measures of heart rate variability in patients with Irritable Bowel Syndrome. Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in 2011. Ninety patients aged 20-50 years of both sex with Irritable bowel syndrome were included in the study group. They were collected from the OPD of Gastroenterology in BSMMU. Age and sex matched 30 apparently healthy subjects served as control. For assessing HRV by time domain method, Mean heart rate Mean R-R interval, Max/Min R-R interval, SDNN, RMSSD, PNN50%, NN50% were recorded by a digital Polyrite. ANOVA, independent sample t-test and Pearson’s correlation coefficient tests were performed as applicable. Results: Mean heart rate were significantly higher and Mean R-R interval, Max/Min R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower in IBS groups compared to those of control. Correlation analysis showed negative correlations of SDNN, RMSSD, PNN50%, NN50% with duration of disease. Conclusion: This study concludes that parasympathetic activity was reduced in patients of IBS. In addition, decreased vagal modulation is inversely related to the duration IBS. DOI: http://dx.doi.org/10.3329/jbsp.v7i2.14451 J Bangladesh Soc Physiol. 2012, December; 7(2): 60-65

scholarly journals Assessment of Autonomic Nerve Function In Hypothyroids By Time Domain Method of Heart Rate Variability

2012 ◽  
Vol 7 (1) ◽  
pp. 48-52
Author(s):  
Matia Ahmed ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Time Domain ◽  
Time Domain Method ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
The Mean ◽  
Hypothyroid Patients ◽  
Serum Tsh

Background: Cardiovascular complications are common in hypothyroids .Time domain measures of HRV is useful to determine the cardiac autonomic regulation by assessing sympathovagal balance.Objective: To assess the cardiac autonomic nerve function activity by time domain measures of heart rate variability in patients with hypothyroidism.Methods: This cross sectional study was carried out in the Department of Physiology, Banghabandhu Sheikh Mujib Medical University between July 2008 to June 2009 on 60 female patients with hypothyroidism aged 30-50 years. 30 age matched apparently healthy euthyroid subjects were also studied as control. Hypothyroid patients were divided into 2 subgroups, one group includes patients on their 1st day of diagnosis, before starting of treatment and another group includes patients with medication for 12-18 months. The patients were selected from the Out Patients Department of Endocrinology Wing BSMMU. Serum TSH and FT4 levels of all subjects were measured by AxSYM system. For assessing HRV by time domain method, mean R-R   interval, mean heart rate, SDNN, RMSSD and variance were measured by a Polyrite. For statistical analysis, Independent Sample t test and One Way ANOVA were used.Results: The mean serum TSH was significantly higher and FT4 was significantly lower (p<0.001) in newly diagnosed hypothyroids than those of control and treated group. In untreated hypothyroid patients the mean values of heart rate, SDNN, RMSSD,variance were found significantly (p<0.001) lower in comparison to both control and treated patients. No significant difference in these hormonal levels and all these time domain measures were found between control and treated group.Conclusion: This study concludes that decrease parasympathetic nerve activity may be a consequence of hypothyroidism, if not treated properly. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11162 J Bangladesh Soc Physiol. 2012, June; 7(1): 48-52

scholarly journals Assessment of Autonomic Nerve Function In Patients With Irritable Bowel Syndrome

2012 ◽  
Vol 7 (1) ◽  
pp. 53-59
Author(s):  
Mohammad Nayem ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Irritable Bowel Syndrome ◽  
Autonomic Nerve ◽  
Total Power ◽  
Heart Rate Variability Analysis ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
Irritable Bowel ◽  
Function Activity

Background: Autonomic nerve function impairment is related to development of Irritable Bowel Syndrome (IBS). Heart rate variability (HRV) is a useful tool to measure autonomic nerve function activity and also sympatho-vagal balance.Objective: To assess autonomic nerve function activity by heart rate variability analysis in patients with Irritable Bowel Syndrome.Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from 1st July 2010 to 30th June 2011. Ninety patients aged 20-50 years of both sexes with Irritable bowel syndrome were included in the study group. They were enrolled from the OPD of Gastroenterology in BSMMU. For comparison age and sex matched 30 apparently healthy subjects were also studied as control. The power spectral HRV parameters were recorded by a digital Polyrite. For statistical analysis ANOVA, independent sample t-test were performed.Results: Mean resting pulse rate, mean HR, SBP, DBP, LF, LF norm and LF/HF were significantly higher(P<0.001) and total power, HF, HF norm were significantly lower(P<0.001) in IBS group compared to those of control.Conclusion: This study concludes markedly lower parasympathetic with concomitant higher sympathetic activity and shifting of sympathovagal balance towards sympathetic predominance in patients of IBS. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11163 J Bangladesh Soc Physiol. 2012, June; 7(1): 53-59

scholarly journals Time Domain Measures Of Heart Rate Variability In Heavy Workers

1970 ◽  
Vol 6 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Sangita Mithun ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Cross Sectional ◽  
Socioeconomic Condition ◽  
Apparently Healthy

Background: Physical inactivity and low resting heart rate variability (HRV) are associated with increased incidence of coronary heart disease. Heavy physical activity is associated with higher heart rate variability and reduces the risk of coronary heart disease Objective: To assess some time domain measures of HRV in order to compare Cardiac Autonomic Function between sedentary and heavy workers. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University between 1st July 2008 to 30th June 2009 on 30 apparently healthy heavy workers aged 28-50 years from low socioeconomic condition (study group). For comparison 30 age, sex, BMI and socioeconomic status matched apparently healthy sedentary subjects (group A) were also studied. The study subjects were selected among rickshaw-pullers living in the slum areas nearby BSMMU, Dhaka and the controls were from fourth class employee of BSMMU, Dhaka. Heart Rate Variability were assessed by a Polygraph. Several time domain measures of HRV such as mean R-R interval, mean HR, SDNN, RMSSD were analyzed. For statistical analysis, Independent-Samples t-test, and Pearson’s correlation coefficient tests were done as applicable. Results: Resting mean heart rate (P<0.01), SDNN (P<0.01) and RMSSD (P<0.001) were significantly lower but mean R-R interval (P<0.001) was significantly higher in heavy workers than those of sedentary control. The mean R-R interval (P<0.05) showed significant positive correlation in heavy workers but significant negative correlation in sedentary workers with BMI. Conclusion: Cardiac autonomic nerve function status may be higher with parasympathetic dominance by increased physical activity. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9755 JBSP 2011 6(2): 77-83

scholarly journals Correlation between Palpitations below the Heart in Traditional Chinese Medicine and Autonomic Nerve Function Based on Heart Rate Variability: A Case-Control Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Chengcheng Song ◽  
Kelong Chen ◽  
Ziqian Wu ◽  
Wei Liu ◽  
Ling Chen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Logistic Regression ◽  
Risk Factor ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Spearman Correlation ◽  
Autonomic Nerve Function

Objective. To explore the autonomic nerve rhythm and the correlation between palpitations below the heart (PBTH) and autonomic nerve function in patients with PBTH based on heart rate variability (HRV). Methods. The outpatients or ward patients of Wenzhou Hospital of Traditional Chinese Medicine were collected and divided into two groups: the PBTH group and the normal group. The HRV of each group was detected. Single-factor statistical methods, Spearman correlation analysis, and logistic regression were used to describe and analyze the rhythm and characteristics of autonomic nerves in patients with PBTH and the correlation between PBTH and autonomic nerve function. Results. (1) In the comparison of HRV in different time periods in the same group, the SDNN, RMSSD, pNN50, TP, and HF in the PBTH group at night were significantly higher than those in the daytime ( P < 0.01 ), while the LF/HF ratio was significantly lower than that in the daytime ( P < 0.01 ). (2) In the comparison of HRV between the two groups in the same time period, the RMSSD and pNN50 of the PBTH group during the daytime period were significantly higher than those of the normal control group ( P < 0.05 ), and the LF/HF was significantly lower than that of the normal group ( P < 0.05 ). (3) In the Spearman correlation analysis, PBTH was significantly correlated with RMSSD, pNN50, and LF/HF ratio in the daytime period, with correlation coefficients of 0.424, 0.462, and −0.524, respectively ( P < 0.05 ). (4) Logistic regression analysis showed that the decrease of LF/HF ratio during the daytime period was an independent risk factor for PBTH in TCM (OR = 0.474, 95% CI: 0.230–0.977, P < 0.05 ). Conclusions. The changes in parasympathetic nerve function in patients with PBTH have a circadian rhythm, which is characterized by increased activity during the nighttime. At the same time, the autonomic nerve activity of people with PBTH during the daytime is unbalanced, and the decrease of LF/HF ratio during the day is an independent high risk factor for PBTH.

scholarly journals Effect of slow breathing exercise on non linear Heart rate variability in transfusion dependent thalassemic patients

2019 ◽  
Vol 14 (1) ◽  
pp. 26-32
Author(s):  
Kamol Chandra Das ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Conventional Treatment ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Breathing Exercise ◽  
Autonomic Nerve Function ◽  
Non Linear ◽  
Healthy Control ◽  
Slow Breathing

Background: Nonlinear measure of heart rate variability (HRV) is an emerging tool to detect changes in cardiac autonomic nerve function (CANF) in transfusion dependent thalassemic (TDT) patients. Slow breathing exercise (SBE) can significantly improve HRV in health and various diseases. Objective: To observe the effect of slow breathing exercise (SBE) on non linear measures of HRV in TDT patients. Methods: This prospective interventional study was done in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in 2018 on 60 male TDT patients aged 15-30 years. Thirty patients received conventional treatment and 30 patients performed slow breathing exercise along with the conventional treatment for 3 months. Age and sex matched 30 healthy control were enrolled. All subjects were followed up at baseline and after 3 months. Non linear (Poincare) HRV parameters were recorded by Power Lab 8/35 AD Instrument, Australia. For statistical analysis paired sample ‘ t’ test and independent sample ‘t’ test were used. Result: SD1, SD2 and SD1/SD2 were found significantly lower in TDT patients compared to healthy control at baseline. After 3 months of slow breathing exercise, significant increment of these parameters occurred with trend of improvement in cardiac autonomic nerve function in this group of patients. Conclusion: Slow breathing exercise may improve cardiac autonomic nerve function and sympathovagal balance in transfusion dependent thalassemic patients. J Bangladesh Soc Physiol. 2019, June; 14(1): 26-32

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