scholarly journals Prevalence and Structural Abnormal Findings of Injured Knee Joint among Adult Patients detected by Magnetic Resonance Imaging Study of 70 Cases in a tertiary hospital of Bangladesh

2021 ◽  
Vol 8 (2) ◽  
pp. 80-84
Author(s):  
Mahbuba Shirin ◽  
Salahuddin Al Azad ◽  
Farzana Alam ◽  
Md Menhazul Islam
Keyword(s):  
Knee Joint ◽  
Medial Meniscus ◽  
Left Knee ◽  
Knee Joints ◽  
Cruciate Ligaments ◽  
Resonance Imaging ◽  
Anterior Cruciate Ligaments ◽  
Study Population ◽  
Anterior Cruciate ◽  
Injured Knee

Background: Magnetic resonance imaging is a very useful diagnostic tool for the detection of abnormalities of injured knee joint. Objective: This present study was performed to see the different abnormalities of injured knee joint detected by MRI among adult patients. Methodology: This cross-sectional study was conducted in the Department of Radiology and Imaging at Bangabandhu Sheikh Mujib Medical University (BSSMU), Dhaka, Bangladesh from January to June 2021 for a period of six months. The patients in the age group of equal or more than 18 years with both male and female who were visiting Department of Orthopaedics at BSMMU, Dhaka with history of knee injuries were subjected to MRI were selected as study population. MRI findings of the knee joint were analyzed for the presence of any signal changes or lesions of varying severity for the structures of menisci, cartilage, bone marrow, tendons and ligaments of injured knee joint. Results: A total number of 65 cases of knee joints were analyzed. The mean with the SD of age of the study population was 35.34±13.371. The left knee (60.0%) was more involved than right knee (40.0%). The lesion in femur and tibia were found in 10(15.4%) cases and 8(12.3%) cases respectively. Out of 65 knee joints there were 41 joints were found the tear of anterior cruciate ligament. The complete, interstial tear in the anterior cruciate ligaments were 26(40.0%) and 15(23.1%) knee joints respectively. However, anterior cruciate ligaments of 24(36.9%) knee joints were found normal. Medial meniscus (36.9%) was more involved than lateral meniscus (18.5%). Conclusion: In conclusion young adult male are more commonly affected their left knee joint with the tearing of complete tear of anterior cruciate ligaments and involvement of medial meniscus. Journal of Current and Advance Medical Research, July 2021;8(2):80-84

scholarly journals Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis

2020 ◽  
Author(s):  
Yalda A. Kharaz ◽  
Yongxiang Fang ◽  
Tim Welting ◽  
Mandy Peffers ◽  
Eithne Comerford
Keyword(s):  
Anterior Cruciate Ligament ◽  
Small Rna ◽  
Cruciate Ligament ◽  
Differentially Expressed ◽  
Knee Joints ◽  
Biological Processes ◽  
Cruciate Ligaments ◽  
Anterior Cruciate Ligaments ◽  
Differentially Expressed Mirnas ◽  
Anterior Cruciate

The anterior cruciate ligaments are susceptible to degeneration, resulting in pain, reduced mobility and development of the degenerative joint disease osteoarthritis. There is currently a paucity of knowledge on how anterior cruciate ligament degeneration and disease can lead to osteoarthritis. Small non-coding RNAs (sncRNAs), such as microRNAs, and small nucleolar RNA, are important regulators of gene expression. We aimed to identify sncRNA profiles of human anterior cruciate ligaments to provide novel insights into their roles in osteoarthritis. RNA was extracted from the anterior cruciate ligaments of non-osteoarthritic knee joints (control) and end-stage osteoarthritis knee joints, used for small RNA sequencing and significantly differentially expressed sncRNAs defined. Bioinformatic analysis was undertaken on the differentially expressed miRNAs and their putative target mRNAs to investigate pathways and biological processes affected. Our analysis identified 184 sncRNA that were differentially expressed between control ACLs derived from osteoarthritic joints with a false discovery adjusted p value<0.05; 68 small nucleolar RNAs, 26 small nuclear RNAs and 90 microRNAs. We identified both novel and previously identified (miR-206, -101, -365 and -29b and -29c) osteoarthritis-related microRNAs and other sncRNAs (including SNORD74, SNORD114, SNORD72) differentially expressed in ligaments derived from osteoarthritic joints. Significant cellular functions deduced by the differentially expressed miRNAs included differentiation of muscle (P<0.001), inflammation (P<1.42E−10), proliferation of chondrocytes (P<0.03), fibrosis (P<0.001) and cell viability (P<0.03). Putative mRNAs were associated with the canonical pathways Hepatic Fibrosis Signalling (P<3.7E-32), and Osteoarthritis (P<2.2E−23). Biological processes included apoptosis (P<1.7E−85), fibrosis (P<1.2E−79), inflammation (P<3.4E−88), necrosis (P<7.2E−88) and angiogenesis (P<5.7E−101). SncRNAs are important regulators of anterior cruciate disease during osteoarthritis and may be used as therapeutic targets to prevent and manage anterior cruciate ligament disease and the resultant osteoarthritis.

Function of the crocodilian anterior cruciate ligaments

2021 ◽  
Author(s):  
Daisuke Suzuki ◽  
Satoshi Yamakawa ◽  
Masaya Iijima ◽  
Hiromichi Fujie
Keyword(s):  
Cruciate Ligaments ◽  
Anterior Cruciate Ligaments ◽  
Anterior Cruciate

scholarly journals Anterior cruciate ligament ganglion: case report

2002 ◽  
Vol 120 (6) ◽  
pp. 195-197 ◽  
Author(s):  
André Pedrinelli ◽  
Fábio Bonini Castellana ◽  
Ricardo Bragança de Vasconcellos Fontes ◽  
Rafael Ferreira Coelho ◽  
Luiz Álvaro de Menezes F°.
Keyword(s):  
Magnetic Resonance Imaging ◽  
Anterior Cruciate Ligament ◽  
Case Report ◽  
Magnetic Resonance ◽  
Cruciate Ligament ◽  
Clinical Signs ◽  
Left Knee ◽  
Pathological Examination ◽  
Resonance Imaging ◽  
Anterior Cruciate

CONTEXT: A ganglion is a cystic formation close to joints or tendinous sheaths, frequently found in the wrist, foot or knee. Intra-articular ganglia of the knee are rare, and most of them are located in the anterior cruciate ligament. The clinical picture for these ganglia comprises pain and movement restrictions in the knee, causing significant impairment to the patient. Symptoms are non-specific, and anterior cruciate ligament ganglia are usually diagnosed through magnetic resonance imaging or arthroscopy. Not all ganglia diagnosed through magnetic resonance imaging need to undergo surgical treatment: only those that cause clinical signs and symptoms do. Surgical results are considered good or excellent in the vast majority of cases. CASE REPORT: A 29-year-old male presented with pain in the left knee during a marathon race. Physical examination revealed limitation in the maximum range of knee extension and pain in the posterior aspect of the left knee. Radiographs of the left knee were normal, but magnetic resonance imaging revealed a multi-lobed cystic structure adjacent to the anterior cruciate ligament, which resembled a ganglion cyst. The mass was removed through arthroscopy, and pathological examination revealed a synovial cyst. Patient recovery was excellent, and he resumed his usual training routine five months later.

scholarly journals THE ROLE OF MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF DEFORMING ARTHROSIS OF PROFESSIONAL ETIOLOGY IN MINERS

2018 ◽  
Vol 5 ◽  
pp. 3-11
Author(s):  
Angela Basanets ◽  
Maria Bulavko
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Knee Joint ◽  
Joint Damage ◽  
Knee Joints ◽  
Prognostic Models ◽  
Diagnostic Efficiency ◽  
Resonance Imaging ◽  
Physical Loading ◽  
Medial Hypertrophy

The paper analyzes the effectiveness of magnetic resonance imaging with cartilage diagram in diagnosing signs of professional deforming arthrosis of knee joints in miners working in conditions of significant physical loading. Aim of the research – to determine of diagnostic efficiency of indicators of magnetic resonance imaging of the knee joint and cartilage diagram in miners of the main occupations suffering from deforming arthrosis. Methods. The research is conducted in 30 miners of basic occupations: 20 mining workers of breakage face (MWBF) and 10 machinists of shearer mining machines (МSMM) have been treated in the inpatient department of occupational pathology of the Lviv Regional Clinical Hospital in 2015-2017 due to deforming arthrosis. Damages of the main anatomical elements of the knee joint with arthrosis were analyzed, visualized initially with the help of MRI, and then - cartilage diagram. Results. According to the MRI data, in miners of the main occupations with arthrosis of the knee joint the posterior cross-shaped ligament are most commonly affected (in 75.0±9.7 % MWBF and 70.0±14.5 % МSMM), damage to the medial collateral ligament are diagnosed less frequently (in 5.0±4.9 % in the MWBF and in 10.0±9.5 % in the МSMM). On average 3.8±0.4 modified elements of the knee joint are visualized in patients, whereas 4.8±0.1 affected areas are visualized on the cartilage diagram (р<0.05). In 86.7±6.2 % patients, in the analysis of cartilage diagram, changes in all five analyzed areas are diagnosed, indicating a higher efficiency of the diagnosis of changes in the structures of the joint with DA of the professional etiology of the method of cartilage diagram compared with MRI. According to the cartilage diagram the most significant changes are noted in the hypertrophy of the femur: among all miners 62.5±0.3 ms (medial) and 62.6±0.4 ms (lateral), in the MWBF group the average time of Т2-delay is the largest in the area of the medial hypertrophy of the femur is 60.9±2.3 ms, in the МSMM group – in the area of the lateral hypertrophy of the femur: 66.7±3.3 ms, which can be linked to the peculiarities of the forced working position of miners of these professions and the kinetics of joint structures. These results can be used to diagnose the initial lesions of joint structures with DA of professional genesis, as well as the creation of prognostic models for determining the the degree of risk of development of knee joint damage, which will allow to improve the system of personified approach to diagnostic and preventive measures in working persons in conditions of considerable physical activity and forced working position.

scholarly journals The Assessment of the Condition of Knee Joint Surfaces with Acoustic Emission Analysis

Sensors ◽  
2021 ◽  
Vol 21 (19) ◽  
pp. 6495
Author(s):  
Bartłomiej Sawaryn ◽  
Natalia Piaseczna ◽  
Szymon Sieciński ◽  
Rafał Doniec ◽  
Konrad Duraj ◽  
...  
Keyword(s):  
Knee Joint ◽  
Knee Injury ◽  
Knee Joints ◽  
Resonance Imaging ◽  
Emission Analysis ◽  
X Ray ◽  
Joint Surfaces ◽  
Magnetic Resonance Imaging Mri ◽  
Leg Movements ◽  
Acoustic Emission Analysis

The knee joint, being the largest joint in the human body, is responsible for a great percentage of leg movements. The diagnosis of the state of knee joints is usually based on X-ray scan, ultrasound imaging, computerized tomography (CT), magnetic resonance imaging (MRI), or arthroscopy. In this study, we aimed to create an inexpensive, portable device for recording the sound produced by the knee joint, and a dedicated application for its analysis. During the study, we examined fourteen volunteers of different ages, including those who had a knee injury. The device effectively enables the recording of the sounds produced by the knee joint, and the spectral analysis used in the application proved its reliability in evaluating the knee joint condition.

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