scholarly journals Relation of Serum Uric Acid Level And Essential Hypertension Among Patients Without Metabolic Syndrome

1970 ◽  
Vol 20 (1) ◽  
pp. 5-8
Author(s):  
MA Kashem ◽  
MZ Hossain ◽  
KMF Ayaz ◽  
MB Alam ◽  
MH Khan ◽  
...  

Objective: To find out and asses the association between hyperuricaemia and hypertension. Methods: A case control study conducted in hypertension clinic, medicine and cardiac outpatient department of DMCH from December 2009 to November 2010 to evaluate association of hyperuricaemia and essential hypertension. A total of 51 hypertensive subjects aged 30 years and above were included as cases with same number of age & sex matched normotensive subjects as control after excluding metabolic syndrome, renal impairment, clinical evidence of liver disease, IBD, malignant diseases, vascular diseases or history of taking relevant drugs by taking detailed history and thorough physical examination and appropriate laboratory investigations. Serum uric acid was measured in all study patients. Results: The mean serum uric acid level was 5.8 ± 1.5 mg/dl vs 4.5 ± 1.2 mg/dl in case and control patients respectively. A total of 13 (25.4%) patients in cases and 5 (9.8%) patients in control had hyperuricaemia (Odds Ratio 3.15, p <0.05). So, the number of hyperuricaemic person & mean serum uric acid level were significantly higher in hypertensive Cases, as Compared to Those of Healthy Normotensive Control. Keywords: Essential hypertension; Serum Uric Acid; Hyperuricaemia DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8563 J Dhaka Med Coll. 2011; 20(1) : 5-8

2020 ◽  
Vol 7 (8) ◽  
pp. 1256
Author(s):  
Piyush Gosar ◽  
Ajay Pal Singh ◽  
Pravi Gosar ◽  
Bhawana Rani

Background: Elevated levels of serum uric acid are associated with increased cardiovascular morbidity and mortality. However, this association with cardiovascular diseases is still unclear, and perhaps controversial. The objective of study was to assess the serum uric acid level in patients with Acute Myocardial Infarction (AMI).Methods: Sixty patients with AMI were studied in Department of Medicine/ Department of Cardiology, J.A. Group of Hospitals between 2016 -2018.Details of age, sex, smoking, alcohol consumption and history of ischemic heart disease (IHD) was obtained and recorded. Serum uric acid level was estimated and compared with control group (healthy subjects).Results: Serum uric acid level was significantly higher among AMI patients (6.43±2.60) as compared to control group (4.05±0.95) (p<0.001). Majority (46.7%) of the AMI patients had uric acid level of >7.1 followed by 20% patients who had uric acid level between 4.5-5.9 (p<0.001). Uric acid level was comparable between smoker and non-smokers (p=0.803), alcoholic and non-alcoholic (p=0.086), hypertensive and non-hypertensive (p=0.668), patients with and without diabetes (p=0.278) and patients with a history of IHD and without history of IHD (p=0.403).Conclusions: Serum uric acid may be useful for prognostication among those with pre-existing AMI.


Author(s):  
Sara Nejatinamini ◽  
Asal Ataie-Jafari ◽  
Mostafa Qorbani ◽  
Shideh Nikoohemat ◽  
Roya Kelishadi ◽  
...  

2015 ◽  
Vol 17 (12) ◽  
pp. 929-935 ◽  
Author(s):  
Kumral Çağlı ◽  
Osman Turak ◽  
Uğur Canpolat ◽  
Fırat Özcan ◽  
Derya Tok ◽  
...  

2011 ◽  
Vol 29 ◽  
pp. e32
Author(s):  
Ju-Mi Lee ◽  
Hyeon Chang Kim ◽  
Hye Min Cho ◽  
Sun Min Oh ◽  
Dong Phil Choi ◽  
...  

2014 ◽  
Vol 20 (3) ◽  
pp. 126 ◽  
Author(s):  
Jong Kil Joo ◽  
Gil Pyo Hong ◽  
Si Eun Han ◽  
Young Ju Lee ◽  
Seung Chul Kim ◽  
...  

2020 ◽  
Vol 7 (7) ◽  
pp. 1136
Author(s):  
SK. Kabir Ahammed ◽  
A. B. M. Kamrul Hasan ◽  
Mohammed Ruhul Kabir ◽  
Gunosindhu Paul ◽  
Shishir Kumar Basak ◽  
...  

Background: The association of hyperuricemia with various cardiovascular risk factors has often led to the debate of whether hyperuricemia is an independent risk factor for essential hypertension (HTN).  The current study was conducted to see the relationship between serum uric acid and essential HTN in Bangladeshi adults.Methods: In this cross-sectional study, conducted in a tertiary hospital of Bangladesh, 155 patients with essential hypertension (newly detected or on treatment) aged ≥18 years and 100 age-sex matched normotensive subjects were investigated. Serum uric acid, plasma glucose, serum creatinine, and lipid profile were measured in all in fasting samples.Results: The frequency of hyperuricemia was higher in the hypertensive group in comparison to the normotensive control group (29.7% vs. 6.0%, p<0.001). Serum uric acid level was higher in the hypertensive subjects than the controls (6.10±0.88 vs. 5.38±0.54 mg/dL, mean±SD, p<0.001). In the hypertensive group, subjects with stage II HTN had higher serum uric acid than those with stage I HTN (6.46±0.83 vs. 5.72±0.78 mg/dL, mean±SD, p<0.001). In the hypertensive group, uric acid level showed significant positive correlations with both systolic and diastolic blood pressure though in the control group uric acid showed such correlation with systolic BP only.Conclusion: Patients with essential hypertension had higher serum uric acid compared to normotensive controls; uric acid level showed positive correlations with systolic and diastolic BP in the hypertensive subjects.


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