scholarly journals Approach to a Child with Irritable Bowel Syndrome: A Review

2017 ◽  
Vol 2 (1) ◽  
pp. 34-39
Author(s):  
Md Rukunuzzaman ◽  
ASM Bazlul Karim ◽  
Wahiduzzaman Mazumder ◽  
Mohammed Nurullah ◽  
Faika Hussain ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Functional Gastrointestinal Disorders ◽  
Physiological Mechanism ◽  
Bowel Habit ◽  
Gastrointestinal Disorders ◽  
Rome Iii Criteria ◽  
Functional Bowel Disorder ◽  
Rome Iii ◽  
Irritable Bowel ◽  
Bowel Disorder

Irritable bowel syndrome (IBS) is one of the most common and best studied disorders among the group of functional gastrointestinal disorders. It is a functional bowel disorder in which abdominal pain or discomfort is associated with defecation or a change in bowel habit. Visceral hypersensitivity and increased GIT motility are the main patho-physiological mechanism for developing IBS. IBS present with diarrhoea or constipation or both. Investigations are least needed for diagnosis of IBS rather done to exclude differential diagnosis. Diagnosis of IBS is done on the basis of Rome-III criteria. Proper counseling, dietary management, antispasmotic and antidepressant are the mainstay of treatment. Journal of National Institute of Neurosciences Bangladesh, 2016;2(1): 34-39

scholarly journals Patterns of alternation in irritable bowel syndrome

2016 ◽  
Vol 89 (2) ◽  
pp. 220-223 ◽  
Author(s):  
Alexandra Chira ◽  
Mihaela Filip ◽  
Dan Lucian Dumitraşcu
Keyword(s):  
Irritable Bowel Syndrome ◽  
Functional Gastrointestinal Disorders ◽  
Structured Interview ◽  
Pharmacological Therapy ◽  
Gastrointestinal Disorders ◽  
Rome Iii Criteria ◽  
Rome Iii ◽  
Stool Form ◽  
Irritable Bowel ◽  
Over Time

Background and aims. Irritable bowel syndrome (IBS) is one of the most frequent functional gastrointestinal disorders, having its subtypes related to the predominant bowel pattern: IBS with diarrhea (IBS-D), IBS with constipation (IBS-C), mixed IBS (IBS-M) or alternating IBS (IBS-A). Some patients alternate between subtypes (IBS-A). We looked for the prevalence of alternation between subtypes in patients with IBS. We also analyzed changes in pharmacological therapy specifically addressed to IBS.Methods. We performed a retrospective observational study that included 60 patients diagnosed with IBS according to Rome III criteria. Patients were asked using a detailed structured interview about their stool form changes regarding previous six months. Alternators were defined as patients that changed IBS subtype over time (previous six months).Results. Out of the 60 patients diagnosed with IBS, 18 patients (30%) were alternators. Of these, 8 patients (44%) changed twice the subtype. Two patients (66.66%) of the IBS-M subgroup shifted between subtypes. Eight patients (44.44%) changed medication over the six months. Four patients (22.2%) of the alternators were on double association of therapy (antispasmodics) addressed to IBS. Four patients (22.22%) discontinued medication.Conclusions. Patients with IBS often change between subtypes even within six months. Alternators in our pilot study represented 30% of IBS patients. IBS-M seems to be the least stable phenotype. The rarest change is the shift between IBS-C and IBS-D. Alternators also often change their pharmacological treatment (antispasmodics).

scholarly journals The role of abuse in the development of irritable bowel syndrome: a comparative study

2003 ◽  
Vol 8 (4) ◽  
pp. 88-98
Author(s):  
G Eileen Rossouw ◽  
Anita D Stuart ◽  
H Gertie Pretorius
Keyword(s):  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Comparative Study ◽  
Full Text ◽  
Bowel Habit ◽  
Functional Bowel Disorder ◽  
Irritable Bowel ◽  
Bowel Disorder

Irritable Bowel Syndrome (IBS) is defined as a chronic relapsing functional bowel disorder of unknown causes which is characterised by attacks of abdominal pain and change of bowel habit resulting in diarrhoea or constipation or both. Opsomming Prikkelbare Dermsindroom (PDS) word gedefinieer as ’n chroniese, herhalende, funksionele ingewandsversteuring wat gekenmerk word deur aanvalle van buikpyn en ‘n verandering in ingewandsgewoontes, wat diarree of hardlywigheid, of beide, tot gevolg het. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals Symptom-based ordinal scale fuzzy clustering of functional gastrointestinal disorders

2020 ◽  
Author(s):  
Marjan Mansourian ◽  
Hamid Reza Marateb ◽  
Ammar Hassanzadeh Keshteli ◽  
Hamed Daghagh Zadeh ◽  
Miquel Angel Mananas ◽  
...  
Keyword(s):  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Ordinal Scale ◽  
Gastrointestinal Disorders ◽  
Rome Iii Criteria ◽  
Gi Symptoms ◽  
Rome Iii ◽  
The Common ◽  
Functional Bloating ◽  
Irritable Bowel

Background The validity of Rome III criteria for diagnosing functional gastrointestinal disorders (FGIDs) have been frequently questioned in the literature. In epidemiology, when a disease is diagnosed, the existence of a true cluster must be proven. Thus, clustering the common GI symptoms of individuals and comparing the clusters with FGIDs defined by the Rome III criteria could provide insights about the validity of FGIDs defined by those criteria. Well-separated compact clusters were detected in responses to questionnaires of the epidemiological features of different FGIDs in Iranian adults using fuzzy ordinal clustering. The representative sample from each cluster i.e. Cluster Representative (CR) was formed whose corresponding FGID was diagnosed with Rome III criteria. Then, FGID diagnosis was performed for all participants in each cluster and the percentage of cases whose FGID was the same as the cluster's identified FGID (agreement) was reported. Results Fourteen valid clusters were detected in 4763 people. The average membership of the objects in each cluster was 77.3%, indicating similarity of the objects in clusters to their corresponding CRs. Eight clusters were assigned to single FGIDs (irritable bowel syndromes: constipation IBS-C, diarrhea IBS-D and un-subtyped IBS-U; functional bloating FB; functional constipation FC; belching disorder BD. The agreement was higher than 50% in single FGID clusters except those whose diagnosis was IBS-U. Conclusions IBS-C, IBS-D, FC, BD, and FB defined with Rome III criteria exist in the population, which is not the case for IBS-U.

Irritable bowel syndrome

2019 ◽  
Vol 12 (9) ◽  
pp. 497-500
Author(s):  
Matthew Sutcliffe
Keyword(s):  
Primary Care ◽  
Irritable Bowel Syndrome ◽  
Abdominal Discomfort ◽  
Bowel Habit ◽  
Gastrointestinal Disorders ◽  
Functional Bowel Disorder ◽  
Delay In Diagnosis ◽  
Altered Bowel Habit ◽  
Irritable Bowel

Irritable bowel syndrome (IBS) is a functional bowel disorder that commonly presents in primary care and has an array of symptoms including abdominal discomfort and altered bowel habit. There may be an overlap of symptoms with other gastrointestinal disorders, leading to difficulty or delay in diagnosis. The condition can produce a variety of troublesome physical and psychological sequelae causing significant impact on an individual’s quality of life. The aim of this article is to highlight the ways in which IBS can present to the General Practitioner and guide the approach to investigation, diagnosis and management in primary care.

scholarly journals PATOGENESIS DAN DIAGNOSIS SINDROM KOLON IRITABEL

2012 ◽  
Vol 4 (3) ◽  
Author(s):  
Edwin Jim
Keyword(s):  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Visceral Hypersensitivity ◽  
Enteric Infection ◽  
Functional Bowel Disorder ◽  
Bowel Habits ◽  
Infection Diagnosis ◽  
Rome Iii ◽  
Irritable Bowel ◽  
Bowel Disorder

Abstract: Irritable bowel syndrome (IBS) is a chronic functional bowel disorder characterized by abdominal pain or discomfort and alterations in bowel habits. Many factors play some important roles in the development of the IBS including abnormal motility, visceral hypersensitivity, and enteric infection. Diagnosis of IBS is based on Rome III criteria.Keywords: irritable bowel syndrome, pathogenesis, diagnosisAbstrak: Sindrom kolon iritabel (SKI) adalah penyakit gastrointestinal fungsional kronik yang ditandai oleh nyeri perut atau rasa tidak enak di perut dan gangguan kebiasaan defekasi. Banyak faktor yang menyebabkan terjadinya SKI antara lain gangguan motilitas, hipersensitivitas viseral, dan pasca infeksi usus. Saat ini kriteria diagnosis yang digunakan untuk SKI ialah kriteria Roma III.Kata kunci: sindrom kolon iritabel, patogenesis, diagnosis

scholarly journals Gastrointestinal Symptoms of Patients with Fabry Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Licia Pensabene ◽  
Simona Sestito ◽  
Angela Nicoletti ◽  
Francesca Graziano ◽  
Pietro Strisciuglio ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Fabry Disease ◽  
Functional Gastrointestinal Disorders ◽  
Rome Iii Criteria ◽  
Functional Bowel Disorder ◽  
Abdominal Bloating ◽  
Gi Symptoms ◽  
Rome Iii ◽  
Functional Bloating ◽  
Bowel Disorder

In order to characterize gastrointestinal (GI) symptoms of 50 patients with Fabry disease (FD) (22 M; age range: 4–70 y; 35 adults and 15 children), validated questionnaires of GI symptoms were used to diagnose the functional gastrointestinal disorders (FGIDs) of the patients with GI symptoms (33/50 (66%); 25/35 adults and 8/15 children) according to Rome III criteria. In 16/25 of these adults and 2/8 of these children, the symptoms mimicked FGID. The adult subgroup included patients with unspecified functional bowel disorder (n=9), functional bloating (n=7), and IBS (n=5), and the child subgroup included patients with abdominal migraine (n=1) and IBS (n=1). Among the 25 adults, 14 reported feeling full after a regular-size meal, and 12 complained of abdominal bloating/distension. All of the children with GI symptoms complained of low abdominal pain associated with changes in the form of the stool/improvements with defecation. In conclusion, according to Rome III criteria, the most frequent diagnoses of FGID among the adults with FD were unspecified functional bowel disorder, followed by functional bloating and IBS. The most frequent GI symptom in the children in our population was IBS-like abdominal pain, while the adults exhibited a full feeling following a regular-size meal and abdominal bloating/distension.

scholarly journals The effects of an artificially enhanced clinoptilolite in patients with irritable bowel syndrome

2017 ◽  
Vol 59 (2) ◽  
pp. 18-22
Author(s):  
Johan C Lamprecht ◽  
Suria Ellis ◽  
Jacques Rene Snyman ◽  
Ilze Laurens
Keyword(s):  
Irritable Bowel Syndrome ◽  
Statistical Significance ◽  
Bowel Habit ◽  
Functional Bowel Disorder ◽  
Intention To Treat ◽  
End Of Treatment ◽  
Rome Iii ◽  
Secondary Endpoints ◽  
Irritable Bowel ◽  
Dose Variation

Background: Irritable Bowel Syndrome (IBS) is one of the most common gastrointestinal disorders presenting in clinical practice. IBS is a functional bowel disorder in which abdominal pain or discomfort is associated with a change in bowel habit and with features of disordered defecation. Methods: IBS candidates were enrolled in the study using the Rome III diagnostic criteria. Participants were identified as IBS-D (diarrhoea dominant), IBS-C (constipation dominant) as well as an IBS-M (mixed group). The participants were randomly assigned; for intention to treat with 750 mg potentiated clinoptilolite three times daily or placebo. The primary endpoint was to determine whether or not the patient experienced adequate relief of symptoms. Results: At the end of treatment 67% and 40% of patients were classified as overall responders in the potentiated clinoptilolite and placebo groups respectively (N=50). After week three of treatment the number of weekly responders was significantly higher (p=0.048) in the potentiated clinoptilolite group compared to the Placebo group, and at week four of treatment the number of weekly responders was borderline significant higher in the potentiated clinoptilolite group (P=0.06). Secondary endpoints were measured but the population size proved too small to realistically obtain statistical significance (p > 0.5). Conclusion: Potentiated clinoptilolite shows clinical benefit, and should be tested further in larger clinical trials. In addition, potentiated clinoptilolite also shows reduced symptoms of IBD-D and IBS-M respectively. It is recommended that clinical response to dose variation should also be further investigated in designated populations of IBS-M and IBS-D patients.

Symptomatic Treatment of Pain-Related Pediatric Functional Gastrointestinal Disorders in a Biopsychosocial Construct, and a Validity Study of Rome III Criteria

2021 ◽  
Vol 60 (6-7) ◽  
pp. 304-313
Author(s):  
Shailender Madani ◽  
Rohit Madani ◽  
Suchi Parikh ◽  
Ahila Manivannan ◽  
Wilma R. Orellana ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Predictive Value ◽  
Functional Gastrointestinal Disorders ◽  
High Specificity ◽  
Symptomatic Treatment ◽  
Gastrointestinal Disorders ◽  
Organic Disease ◽  
Rome Iii Criteria ◽  
Rome Criteria ◽  
Rome Iii

Our study aims to assess improvement with symptomatic treatment of pain-related functional gastrointestinal disorders (FGIDs) in a biopsychosocial construct and evaluate validity of Rome III criteria. Children with chronic abdominal pain diagnosed with an FGID or organic disease were followed for 1 year: 256/334 were diagnosed with an FGID and 78/334 were diagnosed with a possible organic disease due to alarm signs or not meeting Rome III criteria. After 1 year, 251 had true FGID and 46 had organic diseases. Ninety percent of FGID patients improved with symptomatic treatment over an average of 5.4 months. With a 95% confidence interval, Rome criteria predicted FGIDs with sensitivity 0.89, specificity 0.90, positive predictive value 0.98, and negative predictive value 0.59. We conclude that symptomatic treatment of pain-related FGIDs results in clinical improvement and could reduce invasive/expensive testing. Rome III criteria’s high specificity and positive predictive value suggest they can rule in a diagnosis of FGID.

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