scholarly journals Infliximab-related Optic Neuritis in a Patient with Crohn's Disease: a Case Report and Literature Review

2021 ◽  
Vol 62 (8) ◽  
pp. 1160-1166
Author(s):  
Su Hwan Park ◽  
Min Seung Kang ◽  
Sang Yoon Kim ◽  
Ji-Eun Lee ◽  
Su Jin Kim
Keyword(s):  
Visual Acuity ◽  
Crohn’S Disease ◽  
Visual Field ◽  
Crohn's Disease ◽  
Optic Neuritis ◽  
Visual Field Defect ◽  
High Dose ◽  
Infliximab Treatment ◽  
Blurred Vision ◽  
Field Defect

Purpose: We report a case of optic neuritis related to infliximab treatment in a patient with Crohn’s disease, along with a review of the relevant literature.Case summary: A 22-year-male patient complained of blurred vision in the left eye for 2-3 weeks. His best-corrected visual acuity was 8/20 in the left eye. Relative afferent pupillary defect was detected in the left eye and the pupils were of equal size. There was no pain on ocular movement. The results of slit-lamp and fundus examinations were normal. A visual field test revealed a central to inferior visual field defect in the left eye. Orbit magnetic resonance imaging revealed perineural enhancement of the left optic nerve. He had a 5-year history of Crohn’s disease and had been treated with intravenous infliximab (600 mg every 2 weeks). A diagnosis of retrobulbar optic neuritis associated with infliximab was made. He was infused with high-dose methylprednisolone, which was changed to per oral administration. His visual acuity and visual field defect improved after 3 months.Conclusions: Tumor necrosis factor-α inhibitors, such as infliximab, may cause optic neuritis. Therefore, history-taking is important for differential diagnosis and appropriate treatment.

Rapid response to systemic steroid in macular alexandrite laser exposure: Multimodal imaging

2020 ◽  
pp. 112067212092434
Author(s):  
Melike Balikoglu-Yilmaz ◽  
Mahmut Kaya ◽  
Murat Erbezci ◽  
Suleyman Kaynak
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Visual Field ◽  
Visual Field Defect ◽  
Optical Coherence Tomography Angiography ◽  
Hair Removal ◽  
Optical Coherence ◽  
Alexandrite Laser ◽  
Laser Hair Removal ◽  
Field Defect

Purpose To report the management of accidental macular photocoagulation during a 750-nm Alexandrite laser hair removal procedure. Methods Single case report with images. Results A 23-year-old girl presented with an immediate visual field defect in her right eye after direct inadvertent exposure to a single discharge from a 750-nm Alexandrite laser used for laser hair removal. Baseline Snellen visual acuity was 20/20 in the involved right eye but the patient reported a subjective visual field defect. She was treated with oral methylprednisolone that was started at a dose of 1 mg/kg/day and then gradually reduced. Six months after the initial exposure, the final visual acuity was 20/20 and there was a significant improvement in the macular lesion. However, the subjective visual field defect continued. She underwent multimodal retinal imaging with optical coherence tomography, fundus fluorescence angiography, and optical coherence tomography angiography in addition to a visual field test and microperimety. Conclusion The present case documents a gradual visual and anatomical improvement following macular photic damage after accidental occupational exposure to a 750-nm Alexandrite laser. The treatment should be arranged according to the localization of the laser damage. Optical coherence tomography angiography also has the potential to help noninvasively detect choriocapillaris damage.

Inadequacy of self-assessment of vision, and fitness to drive

2017 ◽  
Vol 85 (4) ◽  
pp. 207-209
Author(s):  
John Garfield
Keyword(s):  
Visual Acuity ◽  
Visual Field ◽  
Visual Field Defect ◽  
Daily Activities ◽  
Elderly Persons ◽  
Fitness To Drive ◽  
Self Assessment ◽  
Driving Licence ◽  
Field Defect

The author, a retired neurosurgeon then aged 81, describes his own right upper quadrantic homonymous visual field defect which did not impair any normal daily activities. His own occupation allowed him to recognise the defect. It is unlikely that such a defect would have been noticed by other elderly persons. The field defect shown by perimetry (illustrated) debarred him from driving. Self-assessment of visual acuity, and especially fields, is inadequate when applying for renewal of a driving licence. Effective steps to prevent such licensing and the damage that may follow are discussed.

scholarly journals Nonarteritic Anterior Ischemic Optic Neuropathy following COVID-19 Vaccination: Consequence or Coincidence

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Rika Tsukii ◽  
Yuka Kasuya ◽  
Shinji Makino
Keyword(s):  
Visual Acuity ◽  
Visual Field ◽  
Optic Disc ◽  
Optic Neuropathy ◽  
Visual Field Defect ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Optic Disc Swelling ◽  
The Right ◽  
Field Defect

To report a patient with nonarteritic anterior ischemic optic neuropathy (NA-AION) occurring soon after the COVID-19 vaccination. A 55-year-old woman presented with a 4-day history of inferior visual field disturbance in the right eye 7 days after receiving the first dose of Pfizer-BioNTech COVID-19 vaccine. Examination revealed a best-corrected visual acuity of 20/20 in both eyes. A relative afferent pupillary defect was observed in the right eye. Fundoscopy revealed diffuse optic disc swelling in the right eye, which was prominent above the optic disc. Goldmann visual field testing identified an inferior altitudinal visual field defect with I/2 isopter in the right eye. Although typical complete inferior visual field defect was not detected, a diagnosis of NA-AION was made. The patient was followed without any treatment. During the 2-month follow-up period, the optic disc swelling was gradually improved, and visual acuity was maintained 20/20; however, the optic disc looked diffusely pale in the right eye. Although it is uncertain whether the development of NA-AION after COVID-19 vaccination was consequential or coincidental, we speculate that the close temporal relationship with COVID-19 vaccination suggests the possibility of vasculopathy on the microvascular network of optic nerve head as background of inflammatory or immune-mediated element to the timing of the onset of NA-AION. The aim of this case report is to present this biological plausibility and to elucidate potential ophthalmological complications.

scholarly journals Temporal crescent syndrome caused by a lateral ventricular glioependymal cyst: case report

2020 ◽  
Vol 26 (3) ◽  
pp. 232-236
Author(s):  
Izumi Yamaguchi ◽  
Kyong-Hon Pooh ◽  
Mai Azumi ◽  
Yasushi Takagi
Keyword(s):  
Visual Field ◽  
Visual Field Defect ◽  
Striate Cortex ◽  
The Body ◽  
Blurred Vision ◽  
Anterior Portion ◽  
Glioependymal Cyst ◽  
The Right ◽  
Field Defect

Temporal crescent syndrome is a monocular visual field defect involving the temporal crescent of one eye caused by a retrochiasmal lesion. The most anterior portion of the striate cortex is the only area where the retrochiasmal lesion produces a monocular visual field defect. The authors present the case of a 9-year-old boy who presented with mild headache. MRI revealed a cyst with cerebrospinal fluid signal intensity, occupying the body and trigone of the right lateral ventricle. Conservative treatment with regular clinical and radiological follow-up was chosen because neurological examination findings were normal. Three years later, the patient experienced blurred vision with a temporal crescent defect in the left eye. Endoscopic cyst fenestration was performed, and the pathological findings indicated a glioependymal cyst. After surgery, the monocular temporal crescent disorder was resolved. MRI indicated shrinkage of the cyst and improvement in the narrowing of the anterior calcarine sulcus. These findings suggested that the temporal crescent syndrome was caused by a lateral ventricular glioependymal cyst. This is the first known report of temporal crescent syndrome caused by a lateral ventricular glioependymal cyst. In patients with monocular temporal crescent disorder without intraocular disease, a retrochiasmal lesion in the most anterior portion of the striate cortex should be considered.

scholarly journals Binasal hemianopia in two sisters

2020 ◽  
Vol 13 (1) ◽  
pp. e232486 ◽  
Author(s):  
Sam Scotcher ◽  
George Morphis ◽  
Peter Good
Keyword(s):  
Head Injury ◽  
Visual Field ◽  
Visual Field Defect ◽  
Minor Head Injury ◽  
Teenage Girl ◽  
Blurred Vision ◽  
A Minor ◽  
Field Defect

Binasal hemianopia is a rare visual field defect. A teenage girl presented with blurred vision and persistent headaches following a minor head injury. The ocular examination was normal except for a binasal hemianopia, and subsequent neuroimaging was also unremarkable. Her older sister was found to have the same visual field defect, also with normal neuroimaging. This represents the first reported case of binasal hemianopia found in siblings. Given that no neurological or ocular cause was identified in either sister, this supports the theory of an unknown congenital aetiology.

Optic Neuritis with Visual Field Defect—Possible Ibuprofen-Related Toxicity

2006 ◽  
Vol 40 (3) ◽  
pp. 571-573 ◽  
Author(s):  
Maria-A Gamulescu ◽  
Berthold Schalke ◽  
Gerhard Schuierer ◽  
Veit-P Gabel
Keyword(s):  
Visual Field ◽  
Optic Neuritis ◽  
Visual Field Defect ◽  
Field Defect
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