Risk Factors for Endothelial Cell Loss after Phacoemulsification: Comparison in Different Anterior Chamber Depth Groups

Purpose: To assess the association between anterior chamber depth and endothelial cell loss after phacoemulsication Material and Methods: Ninety patients were recruited for this comparative type of observational study who were further divided into 3 groups according to anterior chamber depth (ACD). All patients underwent phacoemulsication procedure and intraocular implantation. Postoperatively endothelial cell loss (ECL) was calculated by measuring percentage decrease in endothelial cell density of central cornea and regression coefcient between ACD and ECLwas assessed in each group. Results: Endothelial cell loss was signicantly higher in shallow anterior chambers to other groups and the association between ACD and ECLwas signicant only in shallow anterior chamber depth group. Conclusion: Eyes with shallow anterior chamber depth are at higher risk for endothelial cell damage and shows an association between ACD and ECLwhen compared to deep anterior chamber depth.

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Comparative Study of Endothelial Cell Loss after Phacoemulsification in Different Anterior Chamber Depth Groups

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2018/28553.11355 ◽

2018 ◽

Author(s):

Meghna Solanki ◽

Gargi Verma ◽

Ankur Kumar ◽

Kishor Kumar

Keyword(s):

Endothelial Cell ◽

Comparative Study ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Cell Loss ◽

Endothelial Cell Loss

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Dependency of endothelial cell loss on anterior chamber depth within first 4 years after implantation of iris-supported phakic intraocular lenses to treat high myopia

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2016.08.027 ◽

2016 ◽

Vol 42 (11) ◽

pp. 1562-1569 ◽

Cited By ~ 12

Author(s):

Mehdi Shajari ◽

Magdalena Scheffel ◽

Michael Janusz Koss ◽

Thomas Kohnen

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

High Myopia ◽

Anterior Chamber Depth ◽

Cell Loss ◽

Intraocular Lenses ◽

Endothelial Cell Loss ◽

Phakic Intraocular Lenses

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Effects of anterior chamber depth and axial length on corneal endothelial cell density after phacoemulsification

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.35.1.92 ◽

2018 ◽

Vol 35 (1) ◽

Author(s):

Muhammad Khalid ◽

Sameer Shahid Ameen ◽

Nauman Ayub ◽

Mohammad Asim Mehboob

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

Cell Density ◽

Axial Length ◽

Anterior Chamber Depth ◽

Cell Loss ◽

Corneal Endothelial Cell ◽

Endothelial Cell Density ◽

Endothelial Cell Loss ◽

Corneal Endothelial Cell Density

Objective: To evaluate mean decrease in Corneal Endothelial cell Density (CED) after phacoemulsification in patients with different Anterior Chamber Depths (ACDs) and Axial Lengths (ALs). Methods: This prospective stratified controlled study was conducted at PNS Shifa Hospital, Karachi. One hundred eyes of 90 patients, scheduled to undergo phacoemulsification surgery, were included. AL and ACD of each patient were calculated preoperatively using IOL Master. Cataracts were classified according toLens Opacities Classification System III (LOCS III) giving nuclear opalescence (NO) grades on slit lamp examination and only patients with grades NO2 and NO3 were included.Eyes were divided into two groups according to ACD and AL: Group-I: ACD 2.0mm – 3 mm and AL 22mm – 23.5mm; Group-II: ACD 3.1 mm -4.0 mm and AL 23.6mm – 25mm. CED measurements were done preoperatively and 2 month postoperatively using specular microscopy. The difference in CED change (Endothelial Cell Loss) between the two groups after surgery was analyzed using SPSS, v 22; IBM Corporation, Armonk, NY. Results: Differences in gender, laterality, age and preoperative CED between two groups were not significant. Difference in postoperative CED was also not significant, however difference in mean change and mean frequency change in CED between two groups was found to be statistically significant. Conclusion: ACD and AL affect the CED during phacoemulsification and Intraocular Lens(IOL) implantation and can be considered as risk factors of peroperative endothelial cell loss. How to cite this:Khalid M, Ameen SS, Ayub N, Mehboob MA. Effects of anterior chamber depth and axial length on corneal endothelial cell density after phacoemulsification. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.92 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The Effects of Anterior Chamber Depth to Endothelial Cell Loss Using Tranversal Phacoemulsification

Open Journal of Ophthalmology ◽

10.4236/ojoph.2021.113019 ◽

2021 ◽

Vol 11 (03) ◽

pp. 240-248

Author(s):

Budiman

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Cell Loss ◽

Endothelial Cell Loss

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Endothelial cell density change in fully dislocated XEN Gel IMPLANT after trabeculectomy: A case report

European Journal of Ophthalmology ◽

10.1177/1120672121989632 ◽

2021 ◽

pp. 112067212198963

Author(s):

Martina Menchini ◽

Francesco Sartini ◽

Filippo Tatti ◽

Enrico Peiretti ◽

Michele Figus

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

Cell Density ◽

Cell Loss ◽

Endothelial Cell Density ◽

Endothelial Cell Loss ◽

Density Reduction ◽

History Of ◽

Cell Loss Rate

Purpose: To report a case of fully dislocated XEN Gel Implant device into the anterior chamber, 18 months after its implantation and its impact on endothelial cell density. Result: A 75-year-old man with a history of multiple glaucoma surgeries during the last three years presented with an entirely dislocated XEN Gel implant into the anterior chamber. An endothelial cell density reduction was observed over 18 months. Thus, the implant was removed. In the short-term after surgery, the endothelial cell loss rate reduced. Conclusion: XEN Gel Implant can dislocate into the anterior chamber, increasing endothelial cell loss in an eye already underwent multiple surgical procedures with subsequent adverse events. Therefore, if the implant seems displaced, the endothelial cell density should be monitored, and the length of the free-tube segment within the anterior chamber should be measured, during the patient’s follow-up.

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Endothelial Cell Loss With the Choyce Anterior Chamber Lens

American Intra-Ocular Implant Society Journal ◽

10.1016/s0146-2776(79)80006-3 ◽

1979 ◽

Vol 5 (1) ◽

pp. 13-14 ◽

Cited By ~ 6

Author(s):

Charles H. Cozean ◽

Stephen R. Waltman

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

Cell Loss ◽

Endothelial Cell Loss

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Descemet’s Stripping Endothelial Keratoplasty—Insertion Techniques for Endothelial Keratoplasty

US Ophthalmic Review ◽

10.17925/usor.2012.05.01.40 ◽

2012 ◽

Vol 05 (01) ◽

pp. 40

Author(s):

Michael W Belin ◽

Sadeer B Hannush ◽

◽

Keyword(s):

Endothelial Cell ◽

Anterior Chamber ◽

Cell Loss ◽

Endothelial Keratoplasty ◽

Endothelial Cell Loss ◽

Descemet’S Stripping Endothelial Keratoplasty ◽

Insertion Techniques

Descemet’s stripping endothelial keratoplasty has emerged as the treatment of choice for primary and secondary endothelial failure. One of the most crucial portions of the procedure is introducing the donor lenticule into the anterior chamber. Numerous techniques and instruments have been developed in an attempt to simplify the incision and reduce endothelial cell loss.

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