scholarly journals Factors associated with successful response to neurolytic celiac plexus block in patients with upper abdominal cancer-related pain: a retrospective study

2021 ◽  
Vol 34 (4) ◽  
pp. 479-486
Author(s):  
Hyun-Jung Kwon ◽  
Kyunghwan Jang ◽  
Jeong-Gil Leem ◽  
Jin-Woo Shin ◽  
Doo-Hwan Kim ◽  
...  
2014 ◽  
Vol 41 (2) ◽  
pp. 23-26
Author(s):  
MR Khandoker ◽  
ZR Khan ◽  
S Kawsar ◽  
MI Khademul ◽  
KAK Azad

33 patients [13 female] with metastatic intractable upper Abdominal Cancer Pain were treated with celiac plexus neurolytic block with 60% alcohol. Aim of study is to observe the effectiveness of three different techniques of celiac plexus block, unilateral paravertibral, bilateral paravertibral and Paravertibral transaortic approach of celiac plexus blocks under C- arm guidance. Satisfactory pain relief occurs in all three techniques but out- come of transaortic approach a little better than other methods. Pain intensity was assessed by VRS and VAS Scale. Celiac plexus blocks are a suitable technique for upper abdominal visceral metastatic pain. Its effects are prolonged and also increase bowel movement, improve appetite and reduced morphine consumption. This is an initial study and numbers of subject are few. So more study required to get conclusive result. Skilled manpower and appropriate case selection is mandatory for successful results. DOI: http://dx.doi.org/10.3329/bmj.v41i2.18800 Bangladesh Medical Journal 2012 Vol. 41 No. 2: 23-26


2009 ◽  
Vol 6;12 (6;12) ◽  
pp. 1001-1003
Author(s):  
Scott Pello

Introduction: Neurolytic celiac plexus block is a well established intervention to palliate pain, and it potentially improves quality of life in patients suffering from an upper abdominal malignancy, specifically pancreatic cancer. Methods: We describe a 61-year-old female with a history of pancreatic cancer, unexplained transfusion dependent anemia with a normal recent upper endoscopy, and abdominal pain, who had previously undergone gastrojejunostomy and a Roux-en-Y hepaticojejunostomy as well as chemotherapy and radiation therapy. She suffered from intractable abdominal pain and elected to undergo palliative celiac plexus neurolysis. Results: The patient initially appeared to tolerate celiac plexus block well, however, 45 minutes after the procedure, the patient had bright red blood per rectum followed by bloody diarrhea. Her abdomen was soft and non-tender with minimal distention and positive bowel sounds. The patient’s hemoglobin decreased to 7.5 g/dl from 9.0 g/dl, and she received a blood transfusion. Upper endoscopy and enteroscopy demonstrated diffuse hemorrhagic gastritis and duodenitis. The bleeding was controlled and the patient remained hemodynamically stable. Ultimately, the patient did well and was discharged home. Discussion: We report a case of a patient with known history of gastritis and duodenitis, who developed severe upper GI bleeding immediately following the celiac plexus neurolysis. There are no published reports documenting similar cases. It is difficult to offer a precise physiologic explanation for this complication. However, we speculate that inhibition of sympathetic tone from the celiac plexus neurolysis caused increased blood flow to the GI system, and this resulted in active bleeding from previously indolent hemorrhagic gastritis and duodenitis. Conclusion: It may be beneficial for patients with a history of gastritis, duodenitis or GI bleeding to undergo a careful upper GI evaluation prior to celiac plexus neurolysis. Key words: Case report, pancreatic cancer, celiac plexus neurolysis, anemia, hemorrhagic gastritis and doudenitis, sympathetic block


1979 ◽  
Vol 12 (4) ◽  
pp. 407
Author(s):  
Hung Kun Oh ◽  
Yang Sik Shin ◽  
Yong Aee Chun

Pain ◽  
1990 ◽  
Vol 41 ◽  
pp. S91
Author(s):  
S. Jain ◽  
A. Kestenbaum ◽  
N. Shah ◽  
Y. Khan ◽  
L. Rubin

Author(s):  
Samer N. Narouze

There has been a growing interest in ultrasound-guided celiac plexus blocks, especially neurolytic blocks, for terminally ill patients with upper abdominal malignancies. These patients are usually frail and difficult to transfer to the radiology suite. Ultrasound-guided celiac plexus neurolytic block can be performed at the bedside with appropriate monitoring. This chapter focuses on ultrasound guidance. It reviews the advantages of ultrasound compared with other imaging modalities in celiac plexus block as well as the step-by-step technique and how to avoid complications.


2016 ◽  
Vol 05 (04) ◽  
pp. 204-209 ◽  
Author(s):  
Archana Dolly ◽  
Sarita Singh ◽  
Ravi Prakash ◽  
Jaishri Bogra ◽  
Anita Malik ◽  
...  

Abstract Context: Celiac plexus block (CPB) (is an effective way to reduce cancer-associated pain in upper abdominal malignancies. Aims: To evaluate the efficacy and safety of different volumes of 70% alcohol in CPB. Settings and Design: Prospective, randomized, controlled clinical study. Subjects and Methods: Thirty patients of carcinoma gall bladder were randomly divided into three groups (n = 10) to receive 20, 30, and 40 ml of 70% alcohol in CPB. Statistical Analysis Used: All the continuous data were assessed analysis of variance followed by post-hoc tests (Tukey′s Honestly Significant Difference test). Ordinal data were compared using Kruskal-Wallis H-test followed by Mann-Whitney U-test. Categorical comparisons were performed using Chi-square test. Results: A significant difference in visual analog scale (VAS) score of Group I, Group I and Group III was observed from week 6 onward until the end of the study. At all these time intervals, VAS scores in Group I was higher than both Groups II and III during this time interval. VAS scores in Group III were significantly lower as compared to Group II from week 10 onward until the end of the study. As compared to baseline, at all the follow-up intervals, mean morphine requirement was significantly lower in Group II and Group III. A quality of life (QOL) score of Group III were higher as compared to Group I. Between Group II and Group III, significant difference was observed at week 16 only when Group III had a higher score as compared to Group II. Conclusions: VAS score, QOL, and reduction in morphine consumption were increased on increasing the volume of alcohol in CPB, 40 ml being most effective.


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