scholarly journals Risk Factor Analysis for Development of Asymptomatic Carotid Stenosis in Koreans

2006 ◽  
Vol 21 (1) ◽  
pp. 15 ◽  
Author(s):  
Yun Jeong Lim ◽  
Young-Wook Kim ◽  
Yeon Hyen Choe ◽  
Chang-Seok Ki ◽  
Sue Kyung Park
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Carotid Stenosis ◽  
Risk Factor Analysis ◽  
Asymptomatic Carotid Stenosis ◽  
Asymptomatic Carotid

Detected Bruit

2016 ◽  
Author(s):  
Ji Y. Chong ◽  
Michael P. Lerario
Keyword(s):  
Risk Factor ◽  
Carotid Stenosis ◽  
Clinical Characteristics ◽  
Female Gender ◽  
Treatment Decisions ◽  
High Grade ◽  
Asymptomatic Carotid Stenosis ◽  
Asymptomatic Carotid ◽  
Patient Demographic ◽  
Risks And Benefits

Carotid stenosis is a risk factor for stroke. Revascularization of high-grade asymptomatic carotid stenosis in select patients can lower the risk of incident stroke. Endarterectomy and stenting are both associated with periprocedural risk. Risks and benefits need to be evaluated carefully before proceeding with any intervention. Certain patient demographic and clinical characteristics, such as female gender, may reduce the benefits of surgery and influence treatment decisions.

Abstract 3171: Low Stroke Incidence In Asymptomatic Carotid Stenosis Under Optimal Risk Factor Control.

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Maria C Zurru ◽  
Laura Brescacin ◽  
Claudia Alonzo ◽  
Gabriela Orzuza ◽  
Fabiana Ortega ◽  
...  
Keyword(s):  
Risk Factor ◽  
Carotid Stenosis ◽  
Doppler Ultrasonography ◽  
Vascular Risk Factor ◽  
Vascular Risk ◽  
Asymptomatic Carotid Stenosis ◽  
Vascular Events ◽  
Asymptomatic Carotid ◽  
Risk Factor Control

Background: benefits of interventional procedures for the treatment of asymptomatic carotid stenosis (ACS) are still under debate. Our objective was to evaluate the risk of vascular events in a cohort of patients with ACS under optimal medical treatment. Methods: patients with ACS ≥50% were prospectively evaluated. Data on demographic and vascular risk factor profile and control under pharmacological treatment were collected. Severity of carotid stenosis was confirmed by at least two methods (Doppler ultrasonography, angioresonance, angiotomography or digital angiography) and evolution over time was evaluated by Doppler ultrasonography performed by the same operator, blinded to clinical data. Primary end-points were coronary events and ispsilateral ischemic stroke (IIS). Results: ninety two patients were included between January 2007 and December 2010. Mean age was 72±8 years, 35% were women. Mayor vascular risk factors were: hypertension (97%), dyslipidemia (90%), obesity (40%), diabetes (30%), smoking or former smoking (51%), history of coronary heart disease (37%) and peripheral vascular disease (32%). Average follow-up was 667±509 days (range 180-1870 days). Table 1 shows vascular risk factor control during follow-up. One IIS (1.08%; 95% CI 0.19-5.9; 5.8/1000 person/year) and 2 acute myocardial infarction (2.17%; 95% CI 0.6-7.5; 11.73/1000 person/year) were observed. Eighteen percent of patients had stenosis 50-70%, 68% between 70-90% and 13% ≥ 90%. After one year most of patients showed no changes in stenosis severity (76%), 5.56% had progression and 6.52% had regression; 14.1% had no control. Conclusion: optimal pharmacological treatment was related to a very low incidence of vascular events. These data reassert the efficacy of intensive medical treatment in delaying atherosclerotic plaque progression and carotid disease complications.

scholarly journals Rationale, Design, and Implementation of Intensive Risk Factor Treatment in the CREST2 Trial

Stroke ◽  
2020 ◽  
Vol 51 (10) ◽  
pp. 2960-2971
Author(s):  
Tanya N. Turan ◽  
Jenifer H. Voeks ◽  
Marc I. Chimowitz ◽  
Ana Roldan ◽  
Todd LeMatty ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Systolic Blood Pressure ◽  
Carotid Stenosis ◽  
Medical Management ◽  
Density Lipoprotein ◽  
Asymptomatic Carotid Stenosis ◽  
Asymptomatic Carotid ◽  
Risk Factor Management ◽  
The Mean

Background and Purpose: The CREST2 trial (Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis) is comparing intensive medical management (IMM) alone to IMM plus revascularization with carotid endarterectomy or transfemoral carotid artery stenting for preventing stroke or death within 44 days after randomization or ipsilateral ischemic stroke thereafter. There are extensive clinical trial data on outcomes after revascularization of asymptomatic carotid stenosis, but not for IMM. As such, the experimental treatment in CREST2 is IMM, which is described in this article. Methods: IMM consists of aspirin 325 mg/day and intensive risk factor management, primarily targeting systolic blood pressure <130 mm Hg (initially systolic blood pressure <140 mm Hg) and LDL (low-density lipoprotein) cholesterol <70 mg/dL. Secondary risk factor targets focus on tobacco smoking, non-HDL (high-density lipoprotein), HbA1c (hemoglobin A1c), physical activity, and weight. Risk factor management is performed by site personnel and a lifestyle coaching program delivered by telephone. We report interim risk factor data on 1618 patients at baseline and last follow-up through 24 months. Results: The mean baseline LDL of 80.5 mg/dL improved to 66.7 mg/dL. The mean baseline systolic blood pressure of 139.7 mm Hg improved to 130.3 mm Hg. The proportion of patients in-target improved from 43% to 61% for systolic blood pressure <130 mm Hg and from 45% to 67% for LDL<70 mg/dL (both changes P <0.001). Conclusions: The rigorous multimodal approach to intensive stroke risk factor management in CREST2 has resulted in significant improvements in risk factor control that will enable a comparison of cutting-edge medical care to revascularization in patients with asymptomatic carotid stenosis. Registration: URL: https://www.clinicaltrials.gov . Unique identifier: NCT02089217.

Gout Guidelines Highlight Risk Factor Analysis

2006 ◽  
Vol 39 (23) ◽  
pp. 28-29
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Risk Factor Analysis

Risk factor analysis for survival in CardioWest total artificial heart recipients: A pilot study

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
M Dia ◽  
A Zittermann ◽  
E von Rössing ◽  
JF Gummert ◽  
M Morshuis
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Pilot Study ◽  
Artificial Heart ◽  
Total Artificial Heart ◽  
Risk Factor Analysis

Laparatomy after cardiac surgery: a risk factor analysis

2005 ◽  
Vol 53 (S 01) ◽  
Author(s):  
G Szabó ◽  
P Soós ◽  
L Seres ◽  
S Hagl
Keyword(s):  
Factor Analysis ◽  
Cardiac Surgery ◽  
Risk Factor ◽  
Risk Factor Analysis
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