scholarly journals Cytomorphological study of chronic lymphocytic thyroiditis: A correlation between cytological grade with lymphoid: Epithelial ratio, thyroid status and anti-thyroid antibodies

2021 ◽  
Vol 4 (4) ◽  
pp. 166-170
Author(s):  
Dr. Yasmeen Khatib ◽  
Dr. Anumeha Chaturvedi ◽  
Dr. Yogita Sable ◽  
Dr. Manisha Khare ◽  
Dr. Prajakta Gupte ◽  
...  
Keyword(s):  
Chronic Lymphocytic Thyroiditis ◽  
Thyroid Antibodies ◽  
Thyroid Status ◽  
Lymphocytic Thyroiditis

EUTHYROID GOITERS IN CHILDREN: CORRELATION OF NEEDLE BIOPSY WITH OTHER CLINICAL AND LABORATORY FINDINGS IN CHRONIC LYMPHOCYTIC THYROIDITIS AND SIMPLE GOITER

PEDIATRICS ◽  
1969 ◽  
Vol 44 (5) ◽  
pp. 695-708
Author(s):  
Shun M. Ling ◽  
Solomon A. Kaplan ◽  
Jordan J. Weitzman ◽  
George B. Reed ◽  
Gertrude Costin ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Needle Biopsy ◽  
Biopsy Specimen ◽  
Disease Process ◽  
Chronic Lymphocytic Thyroiditis ◽  
Red Cell ◽  
Thyroid Antibodies ◽  
Thyroid Extract ◽  
Laboratory Findings ◽  
Lymphocytic Thyroiditis

All children with euthyroid goiters examined over a period of 3 years underwent study of thyroid function, needle biopsy, and measurement of thyroid antibodies. Sixty-six of 71 children studied had satisfactory biopsies of the thyroid. Of these, 43 (65%) had chronic lymphocytic thyroiditis and 23 (35%) had simple goiter as determined by histologic examination of the biopsy specimen. Elevated titers of anti-thyroid antibodies were found in 50% of the patients with thyroiditis by the tanned red cell method and in 63% by the indirect Coons method. Neither antibody was present in significant quantity in 20% of the patients. Abnormal levels of antibody were rarely detected in children with histologic evidence of simple goiter. Treatment with thyroid extract has little effect on the progression of the disease process to fibrosis and atrophy. Such treatment may be necessary to anticipate the development of hypothyroidism or for replacement if thyroid function is already diminished. There is no evidence that simple goiter is associated with hypothyroidism, and treatment of this disease with thyroid preparations is necessary only for cosmetic purposes. Needle biopsy is the most useful means for making a distinction between thyroiditis and simple goiter.

Chronic lymphocytic thyroiditis

2020 ◽  
Author(s):  
Mehdi Hasnaoui ◽  
Mohamed Masmoudi ◽  
Takwa Belaid ◽  
Khalifa Mighri
Keyword(s):  
Chronic Lymphocytic Thyroiditis ◽  
Lymphocytic Thyroiditis

scholarly journals Epidemiological Study on the Incidence of Chronic Lymphocytic Thyroiditis in Childhood

1976 ◽  
Vol 52 (10) ◽  
pp. 1040-1045 ◽  
Author(s):  
Hiroo NIIMI ◽  
Nozomu SASAKI ◽  
Susumu MATSUMOTO ◽  
Toshio KADOMURA ◽  
Yooko NAKAMURA
Keyword(s):  
Epidemiological Study ◽  
Chronic Lymphocytic Thyroiditis ◽  
Lymphocytic Thyroiditis

Lymphoepithelial Cysts of the Thyroid Gland

2003 ◽  
Vol 127 (4) ◽  
pp. e205-e208
Author(s):  
Elliot Carter ◽  
Ozlem Ulusarac
Keyword(s):  
Thyroid Gland ◽  
Chronic Lymphocytic Thyroiditis ◽  
Chronic Thyroiditis ◽  
Lymphocytic Thyroiditis ◽  
Gland Tissue ◽  
Lymphoepithelial Cysts ◽  
Stratified Squamous Epithelium ◽  
Branchial Cleft ◽  
Solid Cell ◽  
Branchial Cleft Cysts

Abstract We report a case of multiple lymphoepithelial cysts of the thyroid gland in a patient with severe chronic lymphocytic thyroiditis. Lymphoepithelial cysts of the thyroid gland are rare lesions that are histologically similar to branchial cleft cysts found in the lateral neck. The cysts have an epithelial lining that is usually stratified squamous epithelium but may be focally respiratory-type epithelium. Abundant lymphoid tissue is present beneath the epithelium, and lymphoid follicles with reactive germinal centers are common features in the walls of the cysts. Because of their similarity to branchial cleft cysts and the presence of intrathyroidal branchiae-derived structures such as thymus and parathyroid gland tissue in the vicinity of some cysts, lymphoepithelial cysts of the thyroid have been postulated to arise from remnants of branchial derivatives; origination from solid cell nest remnants of the ultimobranchial bodies has been raised as a possibility. A definitive origin, however, has not been established. An association with chronic thyroiditis has been noted in 8 of the previously reported 16 cases occurring in a background of Hashimoto or chronic lymphocytic thyroiditis.

scholarly journals Identifying Risk Factors for a High Lymph Node Ratio (over 0.8) in Papillary Thyroid Carcinoma Patients

2020 ◽  
Author(s):  
Yuewu Liu ◽  
LY Zhang ◽  
xiaoyi li ◽  
hongfeng liu
Keyword(s):  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Ratio ◽  
Male Gender ◽  
Chronic Lymphocytic Thyroiditis ◽  
Papillary Thyroid ◽  
Central Lymph Node ◽  
Lymphocytic Thyroiditis ◽  
Node Ratio ◽  
Central Lymph

Abstract Background Despite the majority of papillary thyroid carcinoma (PTC) patients has an excellent prognosis, central lymph node metastases (CLNM) are common. The relationship between CLNM and prognosis is still controversial, however, a certain lymph node ratio (LNR) has been reported to show significantly worse prognosis for PTC patients. Therefore, the extent of CLNM seems to play an important role in predicting the recurrence and survival of PTC. The aim of this study is to determine the risk factors for a high LNR (over 0.8) in central compartment in PTC patients. Methods A retrospective cohort study was conducted on PTC patients who underwent total thyroidectomy or lobectomy plus central lymph node dissection (CLND) between January 2011 and December 2015. Patients with an LNR over 0.8 was defined as Group A, and patients with an LNR 0 was defined as group B. The clinical and pathological factors such as gender, age, tumor size, tumor number, extracapsular spread (ECS), MACIS score, and co-existence of chronic lymphocytic thyroiditis （CLT）were compared between different LNR groups.Results Univariate analysis found high LNR to be associated with male gender, young age(<40 years) ,larger tumor (≥1 cm), ECS and absence of chronic lymphocytic thyroiditis. Multivariate logistic regression showed male gender (p = 0.007, OR = 3.79), young age(<40 years) (p = 0.000, OR = 0.159), larger tumor (≥1 cm) (p =0.033, OR = 2.530), and absence of chronic lymphocytic thyroiditis (p = 0.036, OR = 0.321) to be independent predictors for high LNR in PTC patients Conclusions Male gender, younger age (<40 years), larger tumor (≥1 cm) and absence of chronic lymphocytic thyroiditis were risk factors of high LNR. We recommend a prophylactic CLND should be considered in PTC patients with such risk factors.

scholarly journals The Risk For Malignancy of the Thyroid Nodule is Modulated by Gender, Echotexture, and Intranodular Lymphocytic Thyroiditis

2019 ◽  
Vol 51 (09) ◽  
pp. 559-567 ◽  
Author(s):  
Salvatore Arena ◽  
Salvatore Benvenga
Keyword(s):  
At Risk ◽  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Chronic Lymphocytic Thyroiditis ◽  
Lymphocytic Thyroiditis ◽  
Malignancy Rate ◽  
Risk Of Malignancy

AbstractBased on the American (Bethesda, 2017) or Italian (SIAPEC 2014) cytological categories of thyroid nodules, the risk of malignancy and management vary. This risk is 5–10% or<3% (benign or TIR2), 6–18% or<10% (AUS/FLUS or TIR3A), 10–40% or 15–30% (FN/SFN or TIR3B), 45–60% or 60–80% (suspicious or TIR4), 94–96% or 95% (malignant or TIR5). In 408 thyroid nodules evaluated cytologically, we computed the malignancy rate in each category considering gender (325 females, 83 males), echotexture (268 isoechoic, 140 hypoechoic), intranodular chronic lymphocytic thyroiditis (ICLT: 113 with and 295 without); histology (263 benign, 145 malignant). It was 0–1.7% for the benign categories, except hypoechoic/ICLT+ve nodules of females (25%); 0–2.3% for the AUS/FLUS category, except isoechoic/ICLT–ve nodules of males (11.1%) and hypoechoic/ICLT–ve nodules of females (22.2%). For the FN/SFN category, rate was the most variable (from 0% in isoechoic/ICLT+ve nodules of males to 100% in hypoechoic/ICLT–ve nodules of males). The 30% threshold for risk was passed in four subgroups, and the 40% threshold in two subgroups (45% in isoechoic/ICLT–ve nodules of males, 80% in hypoechoic/ICLT+ve nodules of females). For the suspicious category, rate was 100% in males, except those with isoechoic/ICLT–ve nodules (75%), and>80% in females with hypoechoic nodules. For the malignant category, rate was always 100%. In conclusion, particular groups of nodules (based on gender, echotexture, and ICLT) within the cytologically benign through the suspiciously malignant category are at risk of malignancy substantially greater (even 100%) than the standard one. Accordingly, the suggested management cannot be standardized.

Increased Incidental Thyroid Cancer in Patients With Subclinical Chronic Lymphocytic Thyroiditis

2020 ◽  
Vol 245 ◽  
pp. 115-118 ◽  
Author(s):  
David Jackson ◽  
Rachel S. Handelsman ◽  
Josefina C. Farrá ◽  
John I. Lew
Keyword(s):  
Thyroid Cancer ◽  
Chronic Lymphocytic Thyroiditis ◽  
Lymphocytic Thyroiditis
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