scholarly journals Fluorescent nanodiamonds quantum sensing free radicals in bio-samples

2021 ◽  
Author(s):  
◽  
Linyan Nie
Small ◽  
2019 ◽  
Vol 15 (22) ◽  
pp. 1900455 ◽  
Author(s):  
Joshua C. Price ◽  
Simon J. Levett ◽  
Valentin Radu ◽  
David A. Simpson ◽  
Aina Mogas Barcons ◽  
...  

2017 ◽  
Vol 19 (17) ◽  
pp. 10748-10752 ◽  
Author(s):  
S. Y. Ong ◽  
M. Chipaux ◽  
A. Nagl ◽  
R. Schirhagl

Fluorescent nanodiamonds are revealed to have flake-like geometries and a preferred orientation in (110) direction. The consequences for their magnetic sensing purposes and performance in experiments for physics and biology are discussed in this paper.


2021 ◽  
Vol 7 (21) ◽  
pp. eabf0573
Author(s):  
L. Nie ◽  
A. C. Nusantara ◽  
V. G. Damle ◽  
R. Sharmin ◽  
E. P. P. Evans ◽  
...  

Free radicals play a vital role in all kinds of biological processes including immune responses. However, free radicals have short lifetimes and are highly reactive, making them difficult to measure using current methods. Here, we demonstrate that relaxometry measurement, or T1, inherited from the field of diamond magnetometry can be used to detect free radicals in living cells with subcellular resolution. This quantum sensing technique is based on defects in diamond, which convert a magnetic signal into an optical signal, allowing nanoscale magnetic resonance measurements. We functionalized fluorescent nanodiamonds (FNDs) to target single mitochondria within macrophage cells to detect the metabolic activity. In addition, we performed measurements on single isolated mitochondria. We were able to detect free radicals generated by individual mitochondria in either living cells or isolated mitochondria after stimulation or inhibition.


Nano Letters ◽  
2021 ◽  
Author(s):  
Linyan Nie ◽  
Anggrek C. Nusantara ◽  
Viraj G. Damle ◽  
Maxim V. Baranov ◽  
Mayeul Chipaux ◽  
...  

2015 ◽  
Vol 6 (2) ◽  
Author(s):  
Nur Hidaayah

Stress conditions in the elderly means an imbalance condition of biological, psychological, and social are closely related to the response to the threats and dangers faced by the elderly. Pressure or interference that is not fun is usually created when the elderly see a mismatch between the state and the 3 systems available resources. Maintenance actions that need to be done there are 2 types, namely : prevention of exposure to a stressor (precipitation factor) and serious treatment of the imbalance condition/ illness (precipitation factor). Prevention includes: sports, hobbies, friendship, avoid eating foods high in free radicals and harmful substances, sex and setting arrangements adequate rest. Habits of the above if done at a young age to avoid exposure to stress in the elderly. Treatment of the imbalance condition / illness, include : drinking water, meditation, eating fresh fruit, and adequate rest.


1988 ◽  
Vol 155 (5) ◽  
pp. 180-180
Author(s):  
Anatolii L. Buchachenko

Author(s):  
Dennis Clouthier ◽  
Phillip Sheridan ◽  
Bing Jin ◽  
Robert Grimminger
Keyword(s):  

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