Rehabilitation aspects of nutritional correction after extensive combined sequity resection

2021 ◽  
pp. 12-18
Author(s):  
L. N. Kostyuchenko ◽  
A. E. Lychkova
Keyword(s):  
Intestinal Resection ◽  
Nutritional Rehabilitation ◽  
Regenerative Processes ◽  
Optimal Scheme ◽  
Metabolic Characteristics

The purpose is the tactics of nutritional rehabilitation after extensive intestinal resection. The metabolic characteristics of the short intestine syndrome and the consequences of combined fine-binding resections, as well as the adaptive and regenerative capabilities of the bowel, are presented. The optimal scheme of nutritional correction for the consequences of combined bowel resections is presented.Conclusion. To stimulate adaptive-regenerative processes in the intestine, it is advisable to use teduglutide (analogue of GLP-2); if ineffective, surgical rehabilitation can be recommended.

scholarly journals Nutritional Rehabilitation in Patients with Malnutrition Due to Crohn’s Disease

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2947 ◽  
Author(s):  
Lidia Santarpia ◽  
Lucia Alfonsi ◽  
Fabiana Castiglione ◽  
Maria Carmen Pagano ◽  
Iolanda Cioffi ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Protein Energy Malnutrition ◽  
Intestinal Resection ◽  
Nutritional Therapy ◽  
Chronic Inflammatory Bowel Disease ◽  
Nutritional Rehabilitation ◽  
Outpatient Unit ◽  
Oral Nutritional Supplements ◽  
Time Required

Background: Crohn’s disease (CD) is a chronic inflammatory bowel disease frequently associated with malabsorption and secondary protein-energy malnutrition (PEM). Methods: Biochemical and clinical data of 63 (34 females, 29 males) patients with PEM due to CD sent to our outpatient unit for nutritional evaluation were retrospectively analyzed. Patients were divided into two groups, according to disease activity. Thirty-eight patients (group A) had the active disease, and 25 patients (group B) suffered from malabsorption resulting from past intestinal resections due to CD. After a physical and hemato-biochemical evaluation at the first visit, all patients received disease-specific personalized dietetic indications. When indicated, oral nutritional supplements, oral/parenteral vitamins, micronutrients, and electrolytes, up to parenteral nutrition, were prescribed. Results: After 1, 3, and 6 months of nutritional therapy, body weight, body mass index (BMI), and serum butyryl-cholinesterase significantly improved in both groups. In 8 out of 13 (61.5%) patients with a cutaneous stoma, intestinal continuity was restored. Conclusions: This study confirms the effectiveness of nutritional rehabilitation and provides information on the time required for nutritional treatment in patients with CD, both during the acute phase and after malabsorption due to intestinal resection.

Clinical and metabolic characteristics in a population of obese tunisian women with polykystic ovary syndrome (pkos)

2019 ◽  
Author(s):  
Chaima Jemai ◽  
Mahjoub Faten ◽  
Sellami Senda ◽  
Alaya Nadia ◽  
Berriche Olfa ◽  
...  
Keyword(s):  
Ovary Syndrome ◽  
Metabolic Characteristics

Neurotransplantation Therapy and Cerebellar Reserve

2018 ◽  
Vol 17 (3) ◽  
pp. 172-183 ◽  
Author(s):  
Jan Cendelin ◽  
Hiroshi Mitoma ◽  
Mario Manto
Keyword(s):  
Neural Plasticity ◽  
Clinical Evidence ◽  
The Self ◽  
Regenerative Processes ◽  
Recovery Capacity ◽  
Cerebellar Ataxias ◽  
Synaptic Formation ◽  
Target Recovery ◽  
Cerebellar Anatomy ◽  
Functional Circuitry

Background & Objective: Neurotransplantation has been recently the focus of interest as a promising therapy to substitute lost cerebellar neurons and improve cerebellar ataxias. However, since cell differentiation and synaptic formation are required to obtain a functional circuitry, highly integrated reproduction of cerebellar anatomy is not a simple process. Rather than a genuine replacement, recent studies have shown that grafted cells rescue surviving cells from neurodegeneration by exerting trophic effects, supporting mitochondrial function, modulating neuroinflammation, stimulating endogenous regenerative processes, and facilitating cerebellar compensatory properties thanks to neural plasticity. On the other hand, accumulating clinical evidence suggests that the self-recovery capacity is still preserved even if the cerebellum is affected by a diffuse and progressive pathology. We put forward the period with intact recovery capacity as “restorable stage” and the notion of reversal capacity as “cerebellar reserve”. Conclusion: The concept of cerebellar reserve is particularly relevant, both theoretically and practically, to target recovery of cerebellar deficits by neurotransplantation. Reinforcing the cerebellar reserve and prolonging the restorable stage can be envisioned as future endpoints of neurotransplantation.

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