FORMULASI NANOEMULGEL EKSTRAK KULIT MANGGIS (Garcinia Mangostana L.)

Antioxidant-containing cosmetic has antiaging therapy that can inhibit the free radical formation. Mangosteen peel extract has very strong antioxidant activity. To enhance the effect and comfortness of mangosteen peel extract use on the skin, it could be made into nanoemulgel. The article provides the information about method of preparation and evaluation of nanoemulsion-gel. The purpose of this study was to formulate a stable microemulgel of mangosteen peel extractusing halal materials declared halal according to Islamic Shari’a. the materials used don’t contain carrion, blood, pig and/ animals that don’t conform to Islamic Shari’a. Microemulgel mangosteen peel extract was made by varying plantacare® 1200 UP concentration as cosurfactant (5, 10, 15, 20 and 25%) in the microemulsion and it was incorporated into the gel base. Evaluations were included the antioxidant activity test and organoleptic, pH, viscosity, stability, particle size analysis and panelist test. The antioxidant activity determined by DPPH method showed that IC50 value of mangosteen peel extract was 5.54 ppm. The third microemulsion formula containing cosurfactant of 15% resulted in the best results in that the parameter of the product can be penetrated by ray laser was at particle size of 23.65 nm, was determined by tranmission Electron Microscopy (TEM). Microemulgel containing Viscolam® MAC 10 of seven percent gave the stable formula proofed by freeze thaw and sentrifuga test. The five microemulgel formulations were stable.

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KARAKTERISASI FISIKOKIMIA DAN AKTIVITAS ANTIOKSIDAN SERAT PANGAN DARI AMPAS EMPULUR SAGU BARUK (Arenga Microcarpha B.)

CHEMISTRY PROGRESS ◽

10.35799/cp.13.1.2020.28931 ◽

2020 ◽

Vol 13 (1) ◽

Author(s):

Nova . ◽

Edi Suryanto ◽

Lidya I. Momuat

Keyword(s):

Antioxidant Activity ◽

Particle Size ◽

Fourier Transform ◽

Dietary Fiber ◽

Particle Size Analysis ◽

Size Analysis ◽

X Ray ◽

Insoluble Dietary Fiber ◽

Infra Red ◽

Ft Ir

Telah dilakukan pengujian potensi aktivitas antioksidan serat pangan dari ampas empulur sagu baruk. Penelitian ini bertujuan untuk mengetahui potensi antioksidan dari ampas empulur sagu baruk. Hasil penelitian menunjukkan bahwa ampas empulur sagu baruk tidak mengalami perubahan mendasar pada komponen utama selama penggilingan ditunjukkan pada hasil spektra Fourier Transform Infra Red (FT-IR). Hasil analisis Particle Size Analysis (PSA) menunjukkan ukuran partikel dari ampas empulur sagu baruk sebesar 92,89 µm. Analisis X-ray Difraction (XRD) menunjukkan adanya karakteristik dari selulosa yang merupakan bagian dari serat pangan tak larut. Hasil pengujian serat pangan didapatkan bahwa ampas empulur sagu baruk memiliki serat pangan total sebesar 68,71% yang meliputi 66,58% serat pangan tak larut dan 2,12% serat pangan larut. Kadar serat pangan tak larut meliputi kadar selulosa, hemiselulosa dan lignin yaitu 50,7%; 29,16%; dan 11,67% secara berturut-turut. Hasil pengujian aktivitas antioksidan metode DPPH dari ekstrak fenolik terikat (EFT) dan fenolik bebas (EFB) ampas empulur sagu baruk menunjukkan aktivitas antioksidan sebesar 66,20% EFB dan 50,97% EFT. Adapun kemampuan penangkal ion nitrit dari sampel ampas sagu baruk kering angin memiliki potensi menangkal ion nitrit sebesar 55,20% EFB dan 50,15% EFT.ABSTRACT Potential antioxidant activity of food fiber from barley sago pith pulp has been tested. This research studies the antioxidant potential of barley sago pith pulp. Fourier Transform Infra Red (FT-IR). The results showed the fact that the barley sago pith pulp did not change the basis of the main components during grinding evaluating the spectral results. The results of the analysis of Particle Size Analysis (PSA) showed that the particle size of the pith sago waste was 92.89 μm. X-ray Difraction (XRD) analysis shows the characteristics of cellulose which is part of insoluble dietary fiber. Food fiber test results were obtained from barley sago pith pulp having a total food fiber of 68.71% which contained 66.58% insoluble food fiber and 2.12% soluble food fiber. Insoluble dietary fiber content includes cellulose, hemicellulose and lignin levels that is 50.7%; 29.16%; and 11.67% consistently. The results of testing the antioxidant activity of DPPH method from phenolic extracts (EFT) and free phenolic (EFB) barley pith pulp showed antioxidant activity of 66.20% EFB and 50.97% EFT. Whereas the ability to prevent nitrite ions from dried barago sago pulp samples has the ability to counteract nitrite ions by 55.20% EFB and 50.15% EFT.

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KARAKTERISASI DAN AKTIVITAS ANTIOKSIDAN SERAT PANGAN DARI DAGING BUAH PALA (MYRISTICA FRAGRANS Houtt)

CHEMISTRY PROGRESS ◽

10.35799/cp.13.1.2020.29661 ◽

2020 ◽

Vol 13 (1) ◽

Author(s):

Christina Tang Dareda ◽

Edi Suryanto ◽

Lidya I. Momuat

Keyword(s):

Antioxidant Activity ◽

Particle Size ◽

Fourier Transform ◽

Chemical Characterization ◽

Particle Size Analysis ◽

Size Analysis ◽

X Ray ◽

Infra Red ◽

Ft Ir ◽

Phenolic Extract

Tujuan dari penelitian ini untuk mengetahui karakteristik fisikokimia dan potensi antioksidan serat pangan dari daging buah pala. Parameter yang digunakan adalah komposisi proksimat, serat pangan, kandungan hemiselulosa, selulosa, lignin, karakteristik gugus fungsi, aktivitas antioksidan, dan kapasitas penangkal nitrit. Hasil karakteristik secara fisik dengan analisis Fourier Transform Infra Red (FT-IR) menunjukkan adanya daerah serapan gugus –OH, -CH, -CH2, C-O-C yang merupakan identifikasi adanya selulosa pada sampel. Hasil analisis Particle Size Analysis (PSA) menunjukkan ukuran partikel dari daging buah pala 137.08 µm. Analisis X-ray Difraction (XRD) menunjukkan adanya karakteristik dari selulosa dari sampel daging buah pala. Hasil karakterisasi secara kimia menunjukkan komposisi kimia dari daging buah pala seperti air (9.11%), abu (3.43%), lemak (1.81%), protein (4.04%), serat kasar (17.57%), serat pangan tak larut (48.61%), serat pangan terlarut (1.67%), serat pangan total (50.28%), hemiselulosa (10.72%), selulosa (15.66%) dan lignin (19.09%). Hasil pengujian aktivitas antioksidan menunjukkan bahwa ekstrak fenolik bebas daging buah pala lebih besar dibandingkan dengan ekstrak fenolik terikat daging buah pala dan aktivitas penangkal nitrit dari daging buah pala menunjukkan bahwa ekstrak fenolik bebas daging buah pala lebih besar dibandingkan dengan ekstrak fenolik terikat daging buah pala.ABSTRACT The purpose of this study was to determine the physicochemical characteristics and antioxidant potential of food fiber from nutmeg meat. The parameters used are proximate composition, dietary fiber, hemicellulose content, cellulose, lignin, functional group characteristics, antioxidant activity, and nitrite repellent capacity. The results of physical characteristics with Fourier Transform Infra Red (FT-IR) analysis showed the absorption area of the -OH, -CH, -CH2, C-O-C groups which was an identification of cellulose in the sample. The results of the Particle Size Analysis (PSA) show the particle size of the nutmeg flesh 137.08 µm. X-ray Difraction (XRD) analysis showed the characteristics of cellulose from nutmeg meat samples. Chemical characterization results showed the chemical composition of nutmeg meat such as water (9.11%), ash (3.43%), fat (1.81%), protein (4.04%), crude fiber (17.57%), insoluble food fiber (48.61% ), dissolved food fiber (1.67%), total food fiber (50.28%), hemicellulose (10.72%), cellulose (15.66%) and lignin (19.09%). The results of antioxidant activity testing showed that the extract of phenolic-free nutmeg was greater than the phenolic extract bound to nutmeg meat and the nitrite-antidote activity of nutmeg showed that the phenolic extract of nutmeg-free flesh was greater than that of phenolic extract bound to nutmeg meat.

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Formulation of Nanoparticles of Ethanol Extract of Garcinia mangostana L. Leaves as Antioxidant with Pectin as Cross-Linker and Chitosan Variation as Polymer

International Journal of Recent Technology and Engineering - 2 ◽

10.35940/ijrte.b1162.0982s919 ◽

2019 ◽

Vol 8 (2S9) ◽

pp. 779-783

Keyword(s):

Particle Size ◽

Ethanolic Extract ◽

Ethanol Extract ◽

Particle Size Analysis ◽

Size Analysis ◽

Garcinia Mangostana ◽

Cross Linker ◽

The Difference ◽

Nano Size

G. mangostana leaves contained xanthone substances, it could be used as antioxidants. Ethanolic extract of G. mangostana leaves were formulated into nanoparticles compound which were made available into nano size through ionic gelation method. G. mangostana leaves were extracted by using maceration method with 50% ethanol as solvent, then were continued with evaporation until thick extract were formed. The nanoparticle formulas were made by mixing G. mangostana extract in ethanol, a solution of chitosan in glacial acetic acid as a polymer, and pectin as a cross-linker solution. There were three formulas (1,2,3) used, with the difference in pectin concentration which were 0.005; 0.01; and 0.02. Characterization of the three formulas include transmittance values were used spectrophotometric method and particle sizes by using particle size analysis (PSA). The results of this research showed that the transmittance of formulations 1, 2 and 3 were 95.9%; 97.7% and 97.3%. The highest transmittance value was formula 3, then were analysed its particle size and zeta potential were 2280 nm and -20.6 mV.

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Ethanol Extract, Ethyl Acetate Extract, Ethyl Acetate Fraction, and n-Heksan Fraction Mangosteen Peels (Garcinia mangostana L.) As Source of Bioactive Substance Free-Radical Scavengers

JPSCR Journal of Pharmaceutical Science and Clinical Research ◽

10.20961/jpscr.v1i2.1936 ◽

2016 ◽

Vol 1 (2) ◽

pp. 71

Author(s):

Liza Pratiwi ◽

Achmad Fudholi ◽

Ronny Martien ◽

Suwidjiyo Pramono

Keyword(s):

Antioxidant Activity ◽

Ethyl Acetate ◽

Ethyl Acetate Extract ◽

Ethanol Extract ◽

Ethyl Acetate Fraction ◽

Hexane Fraction ◽

Garcinia Mangostana ◽

Ic50 Value ◽

Dpph Method ◽

Peel Extract

Mangosteen peels (Garcinia mangostana L.) is well known as an excellent source of antioxidative compounds. The name of mangosteen is xanthone. Antioxidant of mangosteen peels can be extracted by ethanol, etyl acetate and can be fractinated by etyl acetate and n-hexane. The aim of this research was to compare the antioxidant activity of the peel extract by ethanol and etyl acetate and fractinated by etyl acetate and n-hexane. Extract and fraction exhibited higher scavenging activity of DPPH. The purpose of this study was to compare antioxidant activity of ethanol extract, ethyl acetate extract, fraction of ethyl acetate and n-hexane fraction. The antioxidant activity test using DPPH method with UV-Vis spectrophotometer. Ethanol extract shown IC50 value 5,03 µg/mL, ethyl acetate extract shown IC50 value 41,56 µg/mL. Ethyl acetate fraction shown IC50 value 2,78 µg/mL, and n-hexane fraction with IC50 22,33 µg/mL. It means peel extract and fraction by mangosteen peels has very strong antioxidant activity and ethyl acetate fraction that its antioxidant activity higher that the other solvent.

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